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Items: 1 to 20 of 48

1.

Pathologic and biochemical characterization of PrPSc from elk with PRNP polymorphisms at codon 132 after experimental infection with the chronic wasting disease agent.

Moore SJ, Vrentas CE, Hwang S, West Greenlee MH, Nicholson EM, Greenlee JJ.

BMC Vet Res. 2018 Mar 9;14(1):80. doi: 10.1186/s12917-018-1400-9.

2.

Real-Time Quaking-Induced Conversion Detection of Bovine Spongiform Encephalopathy Prions in a Subclinical Steer.

Hwang S, West Greenlee MH, Balkema-Buschmann A, Groschup MH, Nicholson EM, Greenlee JJ.

Front Vet Sci. 2018 Jan 19;4:242. doi: 10.3389/fvets.2017.00242. eCollection 2017.

3.

Differential effects of divalent cations on elk prion protein fibril formation and stability.

Samorodnitsky D, Nicholson EM.

Prion. 2018 Jan 2;12(1):63-71. doi: 10.1080/19336896.2017.1423187. Epub 2018 Jan 31.

4.

Effects of a naturally occurring amino acid substitution in bovine PrP: a model for inherited prion disease in a natural host species.

Vrentas CE, Greenlee JJ, Foster GH, West J, Jahnke MM, Schmidt MT, Nicholson EM.

BMC Res Notes. 2017 Dec 20;10(1):759. doi: 10.1186/s13104-017-3085-8.

6.

Quantitating PrP Polymorphisms Present in Prions from Heterozygous Scrapie-Infected Sheep.

Silva CJ, Erickson-Beltran ML, Hui C, Badiola JJ, Nicholson EM, Requena JR, Bolea R.

Anal Chem. 2017 Jan 3;89(1):854-861. doi: 10.1021/acs.analchem.6b03822. Epub 2016 Dec 21.

PMID:
27936597
7.
8.

Disparate Modes of Evolution Shaped Modern Prion (PRNP) and Prion-Related Doppel (PRND) Variation in Domestic Cattle.

Brunelle BW, O'Grady AM, Nicholson EM, Seabury CM.

PLoS One. 2016 May 25;11(5):e0155924. doi: 10.1371/journal.pone.0155924. eCollection 2016.

9.

Comparison of Two US Sheep Scrapie Isolates Supports Identification as Separate Strains.

Moore SJ, Smith JD, Greenlee MH, Nicholson EM, Richt JA, Greenlee JJ.

Vet Pathol. 2016 Nov;53(6):1187-1196. Epub 2016 Mar 2.

PMID:
26936223
10.

hTERT-immortalized ovine microglia propagate natural scrapie isolates.

Muñoz-Gutiérrez JF, Schneider DA, Baszler TV, Greenlee JJ, Nicholson EM, Stanton JB.

Virus Res. 2015 Feb 16;198:35-43. doi: 10.1016/j.virusres.2014.10.028. Epub 2015 Jan 12.

PMID:
25592246
11.

Detection of the disease-associated form of the prion protein in biological samples.

Nicholson EM.

Bioanalysis. 2015;7(2):253-61. doi: 10.4155/bio.14.301. Review.

PMID:
25587841
12.

Lack of prion accumulation in lymphoid tissues of PRNP ARQ/ARR sheep intracranially inoculated with the agent of scrapie.

Greenlee JJ, Kunkle RA, Richt JA, Nicholson EM, Hamir AN.

PLoS One. 2014 Sep 18;9(9):e108029. doi: 10.1371/journal.pone.0108029. eCollection 2014.

13.

Stability properties of PrP(Sc) from cattle with experimental transmissible spongiform encephalopathies: use of a rapid whole homogenate, protease-free assay.

Vrentas CE, Greenlee JJ, Baron T, Caramelli M, Czub S, Nicholson EM.

BMC Vet Res. 2013 Aug 15;9:167. doi: 10.1186/1746-6148-9-167.

14.

Evaluation of a combinatorial approach to prion inactivation using an oxidizing agent, SDS, and proteinase K.

Smith JD, Nicholson EM, Greenlee JJ.

BMC Vet Res. 2013 Jul 25;9:151. doi: 10.1186/1746-6148-9-151.

15.
16.

Susceptibility of cattle to the agent of chronic wasting disease from elk after intracranial inoculation.

Greenlee JJ, Nicholson EM, Smith JD, Kunkle RA, Hamir AN.

J Vet Diagn Invest. 2012 Nov;24(6):1087-93. doi: 10.1177/1040638712461249. Epub 2012 Sep 18.

PMID:
22991389
17.

Relationships between PrPSc stability and incubation time for United States scrapie isolates in a natural host system.

Vrentas CE, Greenlee JJ, Tatum TL, Nicholson EM.

PLoS One. 2012;7(8):e43060. doi: 10.1371/journal.pone.0043060. Epub 2012 Aug 14.

18.

Clinical and pathologic features of H-type bovine spongiform encephalopathy associated with E211K prion protein polymorphism.

Greenlee JJ, Smith JD, West Greenlee MH, Nicholson EM.

PLoS One. 2012;7(6):e38678. doi: 10.1371/journal.pone.0038678. Epub 2012 Jun 8. Erratum in: PLoS One. 2013;8(1). doi:10.1371/annotation/256348ad-e2eb-40ef-8f0c-fa14475ea5fb.

19.

Prolonged incubation time in sheep with prion protein containing lysine at position 171.

Greenlee JJ, Zhang X, Nicholson EM, Kunkle RA, Hamir AN.

J Vet Diagn Invest. 2012 May;24(3):554-8. doi: 10.1177/1040638712440993.

PMID:
22529124
20.

Acetone precipitation of the scrapie agent results in successful recovery of PrP(Sc) but decreased infectivity.

Smith JD, Greenlee JJ, Foster GH, Nicholson EM.

J Agric Food Chem. 2012 May 9;60(18):4758-62. doi: 10.1021/jf300639h. Epub 2012 Apr 27.

PMID:
22519670

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