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Items: 1 to 20 of 101


Multiregion ultra-deep sequencing reveals early intermixing and variable levels of intratumoral heterogeneity in colorectal cancer.

Suzuki Y, Ng SB, Chua C, Leow WQ, Chng J, Liu SY, Ramnarayanan K, Gan A, Ho DL, Ten R, Su Y, Lezhava A, Lai JH, Koh D, Lim KH, Tan P, Rozen SG, Tan IB.

Mol Oncol. 2017 Feb;11(2):124-139. doi: 10.1002/1878-0261.12012. Epub 2016 Oct 20.


RUNX3 is oncogenic in natural killer/T-cell lymphoma and is transcriptionally regulated by MYC.

Selvarajan V, Osato M, Nah GS, Yan J, Chung TH, Voon DC, Ito Y, Ham MF, Salto-Tellez M, Shimizu N, Choo SN, Fan S, Chng WJ, Ng SB.

Leukemia. 2017 Feb 17. doi: 10.1038/leu.2017.40. [Epub ahead of print]


Individualised multiplexed circulating tumour DNA assays for monitoring of tumour presence in patients after colorectal cancer surgery.

Ng SB, Chua C, Ng M, Gan A, Poon PS, Teo M, Fu C, Leow WQ, Lim KH, Chung A, Koo SL, Choo SP, Ho D, Rozen S, Tan P, Wong M, Burkholder WF, Tan IB.

Sci Rep. 2017 Jan 19;7:40737. doi: 10.1038/srep40737.


LIN28B Activation by PRL-3 Promotes Leukemogenesis and a Stem Cell-like Transcriptional Program in AML.

Zhou J, Chan ZL, Bi C, Lu X, Chong PS, Chooi JY, Cheong LL, Liu SC, Ching YQ, Zhou Y, Osato M, Tan TZ, Ng CH, Ng SB, Wang S, Zeng Q, Chng WJ.

Mol Cancer Res. 2017 Mar;15(3):294-303. doi: 10.1158/1541-7786.MCR-16-0275-T. Epub 2016 Dec 23.


Isochromosome 17q; A Novel Finding in Myeloid Sarcoma.

de Mel S, Lee J, Chua C, Chua SP, Gole L, Poon L, Li J, Ng SB, Liu TC, Chng WJ, Chee YL.

J Clin Exp Hematop. 2016;56(2):130-134. No abstract available.


Aberrant localization of apoptosis protease activating factor-1 in lipid raft sub-domains of diffuse large B cell lymphomas.

Hirpara JL, Loh T, Ng SB, Chng WJ, Pervaiz S.

Oncotarget. 2016 Dec 20;7(51):83964-83975. doi: 10.18632/oncotarget.13336.


Primary cardiac diffuse large B-cell lymphoma in immunocompetent patients: clinical, histologic, immunophenotypic, and genotypic features of 3 cases.

Soon G, Ow GW, Chan HL, Ng SB, Wang S.

Ann Diagn Pathol. 2016 Oct;24:40-6. doi: 10.1016/j.anndiagpath.2016.05.005. Epub 2016 Aug 13.


Expression of melanocytic markers in melanophages across platforms: a potential diagnostic pitfall.

Tan CL, Maheshwari P, Choo SN, Chan YH, Ng SB.

Histopathology. 2017 Feb;70(3):501-504. doi: 10.1111/his.13075. Epub 2016 Nov 15. No abstract available.


Genetic risk of extranodal natural killer T-cell lymphoma: a genome-wide association study.

Li Z, Xia Y, Feng LN, Chen JR, Li HM, Cui J, Cai QQ, Sim KS, Nairismägi ML, Laurensia Y, Meah WY, Liu WS, Guo YM, Chen LZ, Feng QS, Pang CP, Chen LJ, Chew SH, Ebstein RP, Foo JN, Liu J, Ha J, Khoo LP, Chin ST, Zeng YX, Aung T, Chowbay B, Diong CP, Zhang F, Liu YH, Tang T, Tao M, Quek R, Mohamad F, Tan SY, Teh BT, Ng SB, Chng WJ, Ong CK, Okada Y, Raychaudhuri S, Lim ST, Tan W, Peng RJ, Khor CC, Bei JX.

Lancet Oncol. 2016 Sep;17(9):1240-7. doi: 10.1016/S1470-2045(16)30148-6. Epub 2016 Jul 25.


EZH2 phosphorylation by JAK3 mediates a switch to noncanonical function in natural killer/T-cell lymphoma.

Yan J, Li B, Lin B, Lee PT, Chung TH, Tan J, Bi C, Lee XT, Selvarajan V, Ng SB, Yang H, Yu Q, Chng WJ.

Blood. 2016 Aug 18;128(7):948-58. doi: 10.1182/blood-2016-01-690701. Epub 2016 Jun 13.


JAK-STAT and G-protein-coupled receptor signaling pathways are frequently altered in epitheliotropic intestinal T-cell lymphoma.

Nairismägi ML, Tan J, Lim JQ, Nagarajan S, Ng CC, Rajasegaran V, Huang D, Lim WK, Laurensia Y, Wijaya GC, Li ZM, Cutcutache I, Pang WL, Thangaraju S, Ha J, Khoo LP, Chin ST, Dey S, Poore G, Tan LH, Koh HK, Sabai K, Rao HL, Chuah KL, Ho YH, Ng SB, Chuang SS, Zhang F, Liu YH, Pongpruttipan T, Ko YH, Cheah PL, Karim N, Chng WJ, Tang T, Tao M, Tay K, Farid M, Quek R, Rozen SG, Tan P, Teh BT, Lim ST, Tan SY, Ong CK.

Leukemia. 2016 Jun;30(6):1311-9. doi: 10.1038/leu.2016.13. Epub 2016 Feb 8.


IgG4-positive extranodal marginal zone lymphoma arising in Hashimoto's thyroiditis: clinicopathological and cytogenetic features of a hitherto undescribed condition.

Tan CL, Ong YK, Tan SY, Ng SB.

Histopathology. 2016 May;68(6):931-7. doi: 10.1111/his.12854. Epub 2015 Nov 2.


Metachronous B-cell and T-cell post-transplant lymphoproliferative disorders with features of chronic active Epstein-Barr virus infection.

Liu ID, Tan PL, Tan CX, Isa MS, Lau PY, Yeo WS, Chaturvedi S, Villegas MS, Ng KH, Yap HK, Ng SB.

Am J Hematol. 2015 Oct;90(10):E204-5. doi: 10.1002/ajh.24122. Epub 2015 Aug 14. No abstract available.


Stage, age, and EBV status impact outcomes of plasmablastic lymphoma patients: a clinicopathologic analysis of 61 patients.

Loghavi S, Alayed K, Aladily TN, Zuo Z, Ng SB, Tang G, Hu S, Yin CC, Miranda RN, Medeiros LJ, Khoury JD.

J Hematol Oncol. 2015 Jun 10;8:65. doi: 10.1186/s13045-015-0163-z.


High-depth sequencing of over 750 genes supports linear progression of primary tumors and metastases in most patients with liver-limited metastatic colorectal cancer.

Tan IB, Malik S, Ramnarayanan K, McPherson JR, Ho DL, Suzuki Y, Ng SB, Yan S, Lim KH, Koh D, Hoe CM, Chan CY, Ten R, Goh BK, Chung AY, Tan J, Chan CX, Tay ST, Alexander L, Nagarajan N, Hillmer AM, Tang CL, Chua C, Teh BT, Rozen S, Tan P.

Genome Biol. 2015 Feb 12;16:32. doi: 10.1186/s13059-015-0589-1.


Expect the Unexpected: Report of a Case of Pediatric Pharyngeal Extraosseous Plasmacytoma with Tumefactive Amyloidosis ("Amyloidoma") and a Review of the Literature.

Tan CL, Tan SH, Ng SB, Petersson F.

Head Neck Pathol. 2015 Dec;9(4):431-5. doi: 10.1007/s12105-015-0614-4. Epub 2015 Feb 12. Review.


Prognostic implication of morphology, cyclinE2 and proliferation in EBV-associated T/NK lymphoproliferative disease in non-immunocompromised hosts.

Ng SB, Ohshima K, Selvarajan V, Huang G, Choo SN, Miyoshi H, Wang S, Chua HC, Yeoh AE, Quah TC, Koh LP, Tan PL, Chng WJ.

Orphanet J Rare Dis. 2014 Dec 5;9:165. doi: 10.1186/s13023-014-0165-x.


Epstein-Barr virus-associated T/natural killer-cell lymphoproliferative disorder in children and young adults has similar molecular signature to extranodal nasal natural killer/T-cell lymphoma but shows distinctive stem cell-like phenotype.

Ng SB, Ohshima K, Selvarajan V, Huang G, Choo SN, Miyoshi H, Shimizu N, Reghunathan R, Chua HC, Yeoh AE, Quah TC, Koh LP, Tan PL, Chng WJ.

Leuk Lymphoma. 2015;56(8):2408-15. doi: 10.3109/10428194.2014.983099. Epub 2015 Jan 21.


Primary cutaneous NK/T-cell lymphoma, nasal type and CD56-positive peripheral T-cell lymphoma: a cellular lineage and clinicopathologic study of 60 patients from Asia.

Takata K, Hong ME, Sitthinamsuwan P, Loong F, Tan SY, Liau JY, Hsieh PP, Ng SB, Yang SF, Pongpruttipan T, Sukpanichnant S, Kwong YL, Hyeh Ko Y, Cho YT, Chng WJ, Matsushita T, Yoshino T, Chuang SS.

Am J Surg Pathol. 2015 Jan;39(1):1-12. doi: 10.1097/PAS.0000000000000312.


A non-active-site SET domain surface crucial for the interaction of MLL1 and the RbBP5/Ash2L heterodimer within MLL family core complexes.

Shinsky SA, Hu M, Vought VE, Ng SB, Bamshad MJ, Shendure J, Cosgrove MS.

J Mol Biol. 2014 Jun 12;426(12):2283-99. doi: 10.1016/j.jmb.2014.03.011. Epub 2014 Mar 27.

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