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Items: 1 to 20 of 59


Evaluation of Antigen-Conjugated Fluorescent Beads to Identify Antigen-Specific B Cells.

Correa I, Ilieva KM, Crescioli S, Lombardi S, Figini M, Cheung A, Spicer JF, Tutt ANJ, Nestle FO, Karagiannis P, Lacy KE, Karagiannis SN.

Front Immunol. 2018 Mar 23;9:493. doi: 10.3389/fimmu.2018.00493. eCollection 2018.


Innate and adaptive immune traits are differentially affected by genetic and environmental factors.

Mangino M, Roederer M, Beddall MH, Nestle FO, Spector TD.

Nat Commun. 2017 Jan 5;8:13850. doi: 10.1038/ncomms13850.


T Cell-Independent Mechanisms Associated with Neutrophil Extracellular Trap Formation and Selective Autophagy in IL-17A-Mediated Epidermal Hyperplasia.

Suzuki E, Maverakis E, Sarin R, Bouchareychas L, Kuchroo VK, Nestle FO, Adamopoulos IE.

J Immunol. 2016 Dec 1;197(11):4403-4412. Epub 2016 Oct 24.


PAK4 suppresses PDZ-RhoGEF activity to drive invadopodia maturation in melanoma cells.

Nicholas NS, Pipili A, Lesjak MS, Ameer-Beg SM, Geh JL, Healy C, MacKenzie Ross AD, Parsons M, Nestle FO, Lacy KE, Wells CM.

Oncotarget. 2016 Oct 25;7(43):70881-70897. doi: 10.18632/oncotarget.12282.


IgG subclass switching and clonal expansion in cutaneous melanoma and normal skin.

Saul L, Ilieva KM, Bax HJ, Karagiannis P, Correa I, Rodriguez-Hernandez I, Josephs DH, Tosi I, Egbuniwe IU, Lombardi S, Crescioli S, Hobbs C, Villanova F, Cheung A, Geh JL, Healy C, Harries M, Sanz-Moreno V, Fear DJ, Spicer JF, Lacy KE, Nestle FO, Karagiannis SN.

Sci Rep. 2016 Jul 14;6:29736. doi: 10.1038/srep29736.


IgG4 Characteristics and Functions in Cancer Immunity.

Crescioli S, Correa I, Karagiannis P, Davies AM, Sutton BJ, Nestle FO, Karagiannis SN.

Curr Allergy Asthma Rep. 2016 Jan;16(1):7. doi: 10.1007/s11882-015-0580-7. Review.


TGF-β-Induced Transcription Sustains Amoeboid Melanoma Migration and Dissemination.

Cantelli G, Orgaz JL, Rodriguez-Hernandez I, Karagiannis P, Maiques O, Matias-Guiu X, Nestle FO, Marti RM, Karagiannis SN, Sanz-Moreno V.

Curr Biol. 2015 Nov 16;25(22):2899-914. doi: 10.1016/j.cub.2015.09.054. Epub 2015 Oct 29.


Elevated IgG4 in patient circulation is associated with the risk of disease progression in melanoma.

Karagiannis P, Villanova F, Josephs DH, Correa I, Van Hemelrijck M, Hobbs C, Saul L, Egbuniwe IU, Tosi I, Ilieva KM, Kent E, Calonje E, Harries M, Fentiman I, Taylor-Papadimitriou J, Burchell J, Spicer JF, Lacy KE, Nestle FO, Karagiannis SN.

Oncoimmunology. 2015 Jun 3;4(11):e1032492. eCollection 2015 Nov.


The genetic architecture of the human immune system: a bioresource for autoimmunity and disease pathogenesis.

Roederer M, Quaye L, Mangino M, Beddall MH, Mahnke Y, Chattopadhyay P, Tosi I, Napolitano L, Terranova Barberio M, Menni C, Villanova F, Di Meglio P, Spector TD, Nestle FO.

Cell. 2015 Apr 9;161(2):387-403. doi: 10.1016/j.cell.2015.02.046. Epub 2015 Mar 12.


The Characterization of Varicella Zoster Virus-Specific T Cells in Skin and Blood during Aging.

Vukmanovic-Stejic M, Sandhu D, Seidel JA, Patel N, Sobande TO, Agius E, Jackson SE, Fuentes-Duculan J, Suárez-Fariñas M, Mabbott NA, Lacy KE, Ogg G, Nestle FO, Krueger JG, Rustin MHA, Akbar AN.

J Invest Dermatol. 2015 Jul;135(7):1752-1762. doi: 10.1038/jid.2015.63. Epub 2015 Mar 3.


Effects of BRAF mutations and BRAF inhibition on immune responses to melanoma.

Ilieva KM, Correa I, Josephs DH, Karagiannis P, Egbuniwe IU, Cafferkey MJ, Spicer JF, Harries M, Nestle FO, Lacy KE, Karagiannis SN.

Mol Cancer Ther. 2014 Dec;13(12):2769-83. doi: 10.1158/1535-7163.MCT-14-0290. Epub 2014 Nov 10. Review.



Di Meglio P, Villanova F, Nestle FO.

Cold Spring Harb Perspect Med. 2014 Aug 1;4(8). pii: a015354. doi: 10.1101/cshperspect.a015354. Review.


Diverse matrix metalloproteinase functions regulate cancer amoeboid migration.

Orgaz JL, Pandya P, Dalmeida R, Karagiannis P, Sanchez-Laorden B, Viros A, Albrengues J, Nestle FO, Ridley AJ, Gaggioli C, Marais R, Karagiannis SN, Sanz-Moreno V.

Nat Commun. 2014 Jun 25;5:4255. doi: 10.1038/ncomms5255.


Activation of the aryl hydrocarbon receptor dampens the severity of inflammatory skin conditions.

Di Meglio P, Duarte JH, Ahlfors H, Owens ND, Li Y, Villanova F, Tosi I, Hirota K, Nestle FO, Mrowietz U, Gilchrist MJ, Stockinger B.

Immunity. 2014 Jun 19;40(6):989-1001. doi: 10.1016/j.immuni.2014.04.019. Epub 2014 Jun 5.


The IL-23/IL-17 axis in psoriatic arthritis.

Suzuki E, Mellins ED, Gershwin ME, Nestle FO, Adamopoulos IE.

Autoimmun Rev. 2014 Apr-May;13(4-5):496-502. doi: 10.1016/j.autrev.2014.01.050. Epub 2014 Jan 11. Review.


Psoriasis beyond the skin: an expert group consensus on the management of psoriatic arthritis and common co-morbidities in patients with moderate-to-severe psoriasis.

Strohal R, Kirby B, Puig L; Psoriasis Expert Panel, Girolomoni G, Kragballe K, Luger T, Nestle FO, Prinz JC, Ståhle M, Yawalkar N.

J Eur Acad Dermatol Venereol. 2014 Dec;28(12):1661-9. doi: 10.1111/jdv.12350. Epub 2013 Dec 24.


Characterization of innate lymphoid cells in human skin and blood demonstrates increase of NKp44+ ILC3 in psoriasis.

Villanova F, Flutter B, Tosi I, Grys K, Sreeneebus H, Perera GK, Chapman A, Smith CH, Di Meglio P, Nestle FO.

J Invest Dermatol. 2014 Apr;134(4):984-991. doi: 10.1038/jid.2013.477. Epub 2013 Nov 11.


IgG4 antibodies and cancer-associated inflammation: Insights into a novel mechanism of immune escape.

Karagiannis P, Gilbert AE, Nestle FO, Karagiannis SN.

Oncoimmunology. 2013 Jul 1;2(7):e24889. Epub 2013 May 7.


An in-depth characterization of the major psoriasis susceptibility locus identifies candidate susceptibility alleles within an HLA-C enhancer element.

Clop A, Bertoni A, Spain SL, Simpson MA, Pullabhatla V, Tonda R, Hundhausen C, Di Meglio P, De Jong P, Hayday AC, Nestle FO, Barker JN, Bell RJ, Capon F, Trembath RC.

PLoS One. 2013 Aug 19;8(8):e71690. doi: 10.1371/journal.pone.0071690. eCollection 2013.


Gene expression changes with age in skin, adipose tissue, blood and brain.

Glass D, Viñuela A, Davies MN, Ramasamy A, Parts L, Knowles D, Brown AA, Hedman AK, Small KS, Buil A, Grundberg E, Nica AC, Di Meglio P, Nestle FO, Ryten M; UK Brain Expression consortium; MuTHER consortium, Durbin R, McCarthy MI, Deloukas P, Dermitzakis ET, Weale ME, Bataille V, Spector TD.

Genome Biol. 2013 Jul 26;14(7):R75. doi: 10.1186/gb-2013-14-7-r75.

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