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Items: 1 to 20 of 42


Stability of histone post-translational modifications in samples derived from liver tissue and primary hepatic cells.

Gruppuso PA, Boylan JM, Zabala V, Neretti N, Abshiru NA, Sikora JW, Doud EH, Camarillo JM, Thomas PM, Kelleher NL, Sanders JA.

PLoS One. 2018 Sep 7;13(9):e0203351. doi: 10.1371/journal.pone.0203351. eCollection 2018.


The three-dimensional organization of the genome in cellular senescence and age-associated diseases.

Evans SA, Horrell J, Neretti N.

Semin Cell Dev Biol. 2018 Jul 27. pii: S1084-9521(17)30596-7. doi: 10.1016/j.semcdb.2018.07.022. [Epub ahead of print] Review.


Regulation of Cellular Senescence by Polycomb Chromatin Modifiers through Distinct DNA Damage- and Histone Methylation-Dependent Pathways.

Ito T, Teo YV, Evans SA, Neretti N, Sedivy JM.

Cell Rep. 2018 Mar 27;22(13):3480-3492. doi: 10.1016/j.celrep.2018.03.002.


GINOM: A statistical framework for assessing interval overlap of multiple genomic features.

Bryner D, Criscione S, Leith A, Huynh Q, Huffer F, Neretti N.

PLoS Comput Biol. 2017 Jun 15;13(6):e1005586. doi: 10.1371/journal.pcbi.1005586. eCollection 2017 Jun.


The Chromatin Landscape of Cellular Senescence.

Criscione SW, Teo YV, Neretti N.

Trends Genet. 2016 Nov;32(11):751-761. doi: 10.1016/j.tig.2016.09.005. Epub 2016 Sep 28. Review.


Chromatin-modifying genetic interventions suppress age-associated transposable element activation and extend life span in Drosophila.

Wood JG, Jones BC, Jiang N, Chang C, Hosier S, Wickremesinghe P, Garcia M, Hartnett DA, Burhenn L, Neretti N, Helfand SL.

Proc Natl Acad Sci U S A. 2016 Oct 4;113(40):11277-11282. Epub 2016 Sep 12.


Mapping H4K20me3 onto the chromatin landscape of senescent cells indicates a function in control of cell senescence and tumor suppression through preservation of genetic and epigenetic stability.

Nelson DM, Jaber-Hijazi F, Cole JJ, Robertson NA, Pawlikowski JS, Norris KT, Criscione SW, Pchelintsev NA, Piscitello D, Stong N, Rai TS, McBryan T, Otte GL, Nixon C, Clark W, Riethman H, Wu H, Schotta G, Garcia BA, Neretti N, Baird DM, Berger SL, Adams PD.

Genome Biol. 2016 Jul 25;17(1):158. doi: 10.1186/s13059-016-1017-x.


Genome-wide characterization of human L1 antisense promoter-driven transcripts.

Criscione SW, Theodosakis N, Micevic G, Cornish TC, Burns KH, Neretti N, Rodić N.

BMC Genomics. 2016 Jun 14;17:463. doi: 10.1186/s12864-016-2800-5.


Reorganization of chromosome architecture in replicative cellular senescence.

Criscione SW, De Cecco M, Siranosian B, Zhang Y, Kreiling JA, Sedivy JM, Neretti N.

Sci Adv. 2016 Feb 5;2(2):e1500882. doi: 10.1126/sciadv.1500882. eCollection 2016 Feb.


Profiling of the fetal and adult rat liver transcriptome and translatome reveals discordant regulation by the mechanistic target of rapamycin (mTOR).

Boylan JM, Sanders JA, Neretti N, Gruppuso PA.

Am J Physiol Regul Integr Comp Physiol. 2015 Jul 1;309(1):R22-35. doi: 10.1152/ajpregu.00114.2015. Epub 2015 Apr 29.


Enhancement of radiation effect on cancer cells by gold-pHLIP.

Antosh MP, Wijesinghe DD, Shrestha S, Lanou R, Huang YH, Hasselbacher T, Fox D, Neretti N, Sun S, Katenka N, Cooper LN, Andreev OA, Reshetnyak YK.

Proc Natl Acad Sci U S A. 2015 Apr 28;112(17):5372-6. doi: 10.1073/pnas.1501628112. Epub 2015 Apr 13.


Reduced expression of MYC increases longevity and enhances healthspan.

Hofmann JW, Zhao X, De Cecco M, Peterson AL, Pagliaroli L, Manivannan J, Hubbard GB, Ikeno Y, Zhang Y, Feng B, Li X, Serre T, Qi W, Van Remmen H, Miller RA, Bath KG, de Cabo R, Xu H, Neretti N, Sedivy JM.

Cell. 2015 Jan 29;160(3):477-88. doi: 10.1016/j.cell.2014.12.016. Epub 2015 Jan 22.


Drosophila melanogaster show a threshold effect in response to radiation.

Antosh M, Fox D, Hasselbacher T, Lanou R, Neretti N, Cooper LN.

Dose Response. 2014 May 5;12(4):551-81. doi: 10.2203/dose-response.13-047.Antosh. eCollection 2014 Dec.


Transcriptional landscape of repetitive elements in normal and cancer human cells.

Criscione SW, Zhang Y, Thompson W, Sedivy JM, Neretti N.

BMC Genomics. 2014 Jul 11;15:583. doi: 10.1186/1471-2164-15-583.


Dietary switch reveals fast coordinated gene expression changes in Drosophila melanogaster.

Whitaker R, Gil MP, Ding F, Tatar M, Helfand SL, Neretti N.

Aging (Albany NY). 2014 May;6(5):355-68.


Transcriptional response to dietary restriction in Drosophila melanogaster.

Ding F, Gil MP, Franklin M, Ferreira J, Tatar M, Helfand SL, Neretti N.

J Insect Physiol. 2014 Oct;69:101-6. doi: 10.1016/j.jinsphys.2014.05.002. Epub 2014 May 10.


Transposable elements become active and mobile in the genomes of aging mammalian somatic tissues.

De Cecco M, Criscione SW, Peterson AL, Neretti N, Sedivy JM, Kreiling JA.

Aging (Albany NY). 2013 Dec;5(12):867-83.


Dietary and genetic effects on age-related loss of gene silencing reveal epigenetic plasticity of chromatin repression during aging.

Jiang N, Du G, Tobias E, Wood JG, Whitaker R, Neretti N, Helfand SL.

Aging (Albany NY). 2013 Nov;5(11):813-24.


Death by transposition - the enemy within?

Sedivy JM, Kreiling JA, Neretti N, De Cecco M, Criscione SW, Hofmann JW, Zhao X, Ito T, Peterson AL.

Bioessays. 2013 Dec;35(12):1035-43. doi: 10.1002/bies.201300097. Epub 2013 Oct 15.


Hepatic signaling by the mechanistic target of rapamycin complex 2 (mTORC2).

Lamming DW, Demirkan G, Boylan JM, Mihaylova MM, Peng T, Ferreira J, Neretti N, Salomon A, Sabatini DM, Gruppuso PA.

FASEB J. 2014 Jan;28(1):300-15. doi: 10.1096/fj.13-237743. Epub 2013 Sep 26.

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