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Items: 1 to 20 of 151

1.

Publisher Correction: MSK1 regulates luminal cell differentiation and metastatic dormancy in ER+ breast cancer.

Gawrzak S, Rinaldi L, Gregorio S, Arenas EJ, Salvador F, Urosevic J, Figueras-Puig C, Rojo F, Del Barco Barrantes I, Cejalvo JM, Palafox M, Guiu M, Berenguer-Llergo A, Symeonidi A, Bellmunt A, Kalafatovic D, Arnal-Estapé A, Fernández E, Müllauer B, Groeneveld R, Slobodnyuk K, Stephan-Otto Attolini C, Saura C, Arribas J, Cortes J, Rovira A, Muñoz M, Lluch A, Serra V, Albanell J, Prat A, Nebreda AR, Benitah SA, Gomis RR.

Nat Cell Biol. 2018 Apr 19. doi: 10.1038/s41556-018-0052-0. [Epub ahead of print]

PMID:
29674681
2.

Age-dependent regulation of antioxidant genes by p38α MAPK in the liver.

Pérez S, Rius-Pérez S, Tormos AM, Finamor I, Nebreda ÁR, Taléns-Visconti R, Sastre J.

Redox Biol. 2018 Jun;16:276-284. doi: 10.1016/j.redox.2018.02.017. Epub 2018 Feb 17.

3.

TGFβ drives immune evasion in genetically reconstituted colon cancer metastasis.

Tauriello DVF, Palomo-Ponce S, Stork D, Berenguer-Llergo A, Badia-Ramentol J, Iglesias M, Sevillano M, Ibiza S, Cañellas A, Hernando-Momblona X, Byrom D, Matarin JA, Calon A, Rivas EI, Nebreda AR, Riera A, Attolini CS, Batlle E.

Nature. 2018 Feb 22;554(7693):538-543. doi: 10.1038/nature25492. Epub 2018 Feb 14.

PMID:
29443964
4.

MSK1 regulates luminal cell differentiation and metastatic dormancy in ER+ breast cancer.

Gawrzak S, Rinaldi L, Gregorio S, Arenas EJ, Salvador F, Urosevic J, Figueras-Puig C, Rojo F, Del Barco Barrantes I, Cejalvo JM, Palafox M, Guiu M, Berenguer-Llergo A, Symeonidi A, Bellmunt A, Kalafatovic D, Arnal-Estapé A, Fernández E, Müllauer B, Groeneveld R, Slobodnyuk K, Stephan-Otto Attolini C, Saura C, Arribas J, Cortes J, Rovira A, Muñoz M, Lluch A, Serra V, Albanell J, Prat A, Nebreda AR, Benitah SA, Gomis RR.

Nat Cell Biol. 2018 Feb;20(2):211-221. doi: 10.1038/s41556-017-0021-z. Epub 2018 Jan 22. Erratum in: Nat Cell Biol. 2018 Apr 19;:.

PMID:
29358704
5.

Regulation of Mammary Luminal Cell Fate and Tumorigenesis by p38α.

Del Barco Barrantes I, Stephan-Otto Attolini C, Slobodnyuk K, Igea A, Gregorio S, Gawrzak S, Gomis RR, Nebreda AR.

Stem Cell Reports. 2018 Jan 9;10(1):257-271. doi: 10.1016/j.stemcr.2017.11.021. Epub 2017 Dec 28.

6.

Regulation of Androgen Receptor Activity by Transient Interactions of Its Transactivation Domain with General Transcription Regulators.

De Mol E, Szulc E, Di Sanza C, Martínez-Cristóbal P, Bertoncini CW, Fenwick RB, Frigolé-Vivas M, Masín M, Hunter I, Buzón V, Brun-Heath I, García J, De Fabritiis G, Estébanez-Perpiñá E, McEwan IJ, Nebreda ÁR, Salvatella X.

Structure. 2018 Jan 2;26(1):145-152.e3. doi: 10.1016/j.str.2017.11.007. Epub 2017 Dec 7.

PMID:
29225078
7.

Induction of oxidative metabolism by the p38α/MK2 pathway.

Trempolec N, Muñoz JP, Slobodnyuk K, Marin S, Cascante M, Zorzano A, Nebreda AR.

Sci Rep. 2017 Sep 12;7(1):11367. doi: 10.1038/s41598-017-11309-7.

8.

Failure to Inactivate Nuclear GSK3β by Ser389-Phosphorylation Leads to Focal Neuronal Death and Prolonged Fear Response.

Thornton TM, Hare B, Colié S, Pendlebury WW, Nebreda AR, Falls W, Jaworski DM, Rincon M.

Neuropsychopharmacology. 2018 Jan;43(2):393-405. doi: 10.1038/npp.2017.187. Epub 2017 Aug 17.

PMID:
28832021
9.

p38α regulates cytokine-induced IFNγ secretion via the Mnk1/eIF4E pathway in Th1 cells.

Salvador-Bernáldez M, Mateus SB, Del Barco Barrantes I, Arthur SC, Martínez-A C, Nebreda AR, Salvador JM.

Immunol Cell Biol. 2017 Oct;95(9):814-823. doi: 10.1038/icb.2017.51. Epub 2017 Jun 14.

PMID:
28611474
10.

Resistance to Taxanes in Triple-Negative Breast Cancer Associates with the Dynamics of a CD49f+ Tumor-Initiating Population.

Gómez-Miragaya J, Palafox M, Paré L, Yoldi G, Ferrer I, Vila S, Galván P, Pellegrini P, Pérez-Montoyo H, Igea A, Muñoz P, Esteller M, Nebreda AR, Urruticoechea A, Morilla I, Pernas S, Climent F, Soler-Monso MT, Petit A, Serra V, Prat A, González-Suárez E.

Stem Cell Reports. 2017 May 9;8(5):1392-1407. doi: 10.1016/j.stemcr.2017.03.026. Epub 2017 Apr 27.

11.

Changes in the free-energy landscape of p38α MAP kinase through its canonical activation and binding events as studied by enhanced molecular dynamics simulations.

Kuzmanic A, Sutto L, Saladino G, Nebreda AR, Gervasio FL, Orozco M.

Elife. 2017 Apr 26;6. pii: e22175. doi: 10.7554/eLife.22175.

12.

Neuronal p38α mediates synaptic and cognitive dysfunction in an Alzheimer's mouse model by controlling β-amyloid production.

Colié S, Sarroca S, Palenzuela R, Garcia I, Matheu A, Corpas R, Dotti CG, Esteban JA, Sanfeliu C, Nebreda AR.

Sci Rep. 2017 Mar 31;7:45306. doi: 10.1038/srep45306.

13.

A Drosophila model of myeloproliferative neoplasm reveals a feed-forward loop in the JAK pathway mediated by p38 MAPK signalling.

Terriente-Félix A, Pérez L, Bray SJ, Nebreda AR, Milán M.

Dis Model Mech. 2017 Apr 1;10(4):399-407. doi: 10.1242/dmm.028118. Epub 2017 Feb 24.

14.

p38α regulates actin cytoskeleton and cytokinesis in hepatocytes during development and aging.

Tormos AM, Rius-Pérez S, Jorques M, Rada P, Ramirez L, Valverde ÁM, Nebreda ÁR, Sastre J, Taléns-Visconti R.

PLoS One. 2017 Feb 6;12(2):e0171738. doi: 10.1371/journal.pone.0171738. eCollection 2017.

15.

Quantification of Pathway Cross-talk Reveals Novel Synergistic Drug Combinations for Breast Cancer.

Jaeger S, Igea A, Arroyo R, Alcalde V, Canovas B, Orozco M, Nebreda AR, Aloy P.

Cancer Res. 2017 Jan 15;77(2):459-469. doi: 10.1158/0008-5472.CAN-16-0097. Epub 2016 Nov 22.

16.

New insights into Cdk2 regulation during meiosis.

Isoda M, Mikolcevic P, Nebreda AR.

Cell Cycle. 2016 Oct 17;15(20):2681-2. doi: 10.1080/15384101.2016.1204856. Epub 2016 Jul 6. No abstract available.

17.

Essential role of the Cdk2 activator RingoA in meiotic telomere tethering to the nuclear envelope.

Mikolcevic P, Isoda M, Shibuya H, del Barco Barrantes I, Igea A, Suja JA, Shackleton S, Watanabe Y, Nebreda AR.

Nat Commun. 2016 Mar 30;7:11084. doi: 10.1038/ncomms11084.

18.

Gene Dosage Imbalance Contributes to Chromosomal Instability-Induced Tumorigenesis.

Clemente-Ruiz M, Murillo-Maldonado JM, Benhra N, Barrio L, Pérez L, Quiroga G, Nebreda AR, Milán M.

Dev Cell. 2016 Feb 8;36(3):290-302. doi: 10.1016/j.devcel.2016.01.008.

19.

Long term p38-a deficiency up-regulates antioxidant enzymes through compensatory NF-?B activation.

Tormos AM, Pérez-Garrido S, Taléns-Visconti R, Nebreda ÁR, Sastre J.

Free Radic Biol Med. 2014 Oct;75 Suppl 1:S52. doi: 10.1016/j.freeradbiomed.2014.10.823. Epub 2014 Dec 10.

PMID:
26461407
20.

The Stress Kinase p38α as a Target for Cancer Therapy.

Igea A, Nebreda AR.

Cancer Res. 2015 Oct 1;75(19):3997-4002. doi: 10.1158/0008-5472.CAN-15-0173. Epub 2015 Sep 16. Review.

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