Format
Sort by
Items per page

Send to

Choose Destination

Search results

Items: 1 to 20 of 261

  • The following term was ignored: -
  • See the search details.
1.

Biobank-driven genomic discovery yields new insight into atrial fibrillation biology.

Nielsen JB, Thorolfsdottir RB, Fritsche LG, Zhou W, Skov MW, Graham SE, Herron TJ, McCarthy S, Schmidt EM, Sveinbjornsson G, Surakka I, Mathis MR, Yamazaki M, Crawford RD, Gabrielsen ME, Skogholt AH, Holmen OL, Lin M, Wolford BN, Dey R, Dalen H, Sulem P, Chung JH, Backman JD, Arnar DO, Thorsteinsdottir U, Baras A, O'Dushlaine C, Holst AG, Wen X, Hornsby W, Dewey FE, Boehnke M, Kheterpal S, Mukherjee B, Lee S, Kang HM, Holm H, Kitzman J, Shavit JA, Jalife J, Brummett CM, Teslovich TM, Carey DJ, Gudbjartsson DF, Stefansson K, Abecasis GR, Hveem K, Willer CJ.

Nat Genet. 2018 Jul 30. doi: 10.1038/s41588-018-0171-3. [Epub ahead of print]

PMID:
30061737
2.

Deletion of Nkx2-5 in trabecular myocardium reveals the developmental origins of pathological heterogeneity associated with ventricular non-compaction cardiomyopathy.

Choquet C, Nguyen THM, Sicard P, Buttigieg E, Tran TT, Kober F, Varlet I, Sturny R, Costa MW, Harvey RP, Nguyen C, Rihet P, Richard S, Bernard M, Kelly RG, Lalevée N, Miquerol L.

PLoS Genet. 2018 Jul 6;14(7):e1007502. doi: 10.1371/journal.pgen.1007502. eCollection 2018 Jul. Erratum in: PLoS Genet. 2018 Aug 15;14(8):e1007610.

3.

G-protein receptor kinases 2, 5 and 6 redundantly modulate Smoothened-GATA transcriptional crosstalk in fetal mouse hearts.

Franco A, Zhang L, Matkovich SJ, Kovacs A, Dorn GW 2nd.

J Mol Cell Cardiol. 2018 Jun 30;121:60-68. doi: 10.1016/j.yjmcc.2018.06.009. [Epub ahead of print]

PMID:
29969579
4.

ETV1 activates a rapid conduction transcriptional program in rodent and human cardiomyocytes.

Shekhar A, Lin X, Lin B, Liu FY, Zhang J, Khodadadi-Jamayran A, Tsirigos A, Bu L, Fishman GI, Park DS.

Sci Rep. 2018 Jul 2;8(1):9944. doi: 10.1038/s41598-018-28239-7.

5.

Heterogeneity of adult masseter muscle satellite cells with cardiomyocyte differentiation potential.

Huang W, Liang J, Feng Y, Jia Z, Jiang L, Cai W, Paul C, Gu JG, Stambrook PJ, Millard RW, Zhu XL, Zhu P, Wang Y.

Exp Cell Res. 2018 May 26. pii: S0014-4827(18)30299-4. doi: 10.1016/j.yexcr.2018.05.028. [Epub ahead of print]

PMID:
29842877
6.

Reactivation of the Nkx2.5 cardiac enhancer after myocardial infarction does not presage myogenesis.

Deutsch MA, Doppler SA, Li X, Lahm H, Santamaria G, Cuda G, Eichhorn S, Ratschiller T, Dzilic E, Dreßen M, Eckart A, Stark K, Massberg S, Bartels A, Rischpler C, Gilsbach R, Hein L, Fleischmann BK, Wu SM, Lange R, Krane M.

Cardiovasc Res. 2018 Jul 1;114(8):1098-1114. doi: 10.1093/cvr/cvy069.

PMID:
29579159
7.

Cardiac Actions of a Small Molecule Inhibitor Targeting GATA4-NKX2-5 Interaction.

Kinnunen SM, Tölli M, Välimäki MJ, Gao E, Szabo Z, Rysä J, Ferreira MPA, Ohukainen P, Serpi R, Correia A, Mäkilä E, Salonen J, Hirvonen J, Santos HA, Ruskoaho H.

Sci Rep. 2018 Mar 15;8(1):4611. doi: 10.1038/s41598-018-22830-8.

8.

Maternal NO2 exposure induces cardiac hypertrophy in male offspring via ROS-HIF-1α transcriptional regulation and aberrant DNA methylation modification of Csx/Nkx2.5.

Zhang Y, Yan W, Ji X, Yue H, Li G, Sang N.

Arch Toxicol. 2018 Apr;92(4):1563-1579. doi: 10.1007/s00204-018-2166-3. Epub 2018 Feb 7.

PMID:
29417167
9.

A context-specific cardiac β-catenin and GATA4 interaction influences TCF7L2 occupancy and remodels chromatin driving disease progression in the adult heart.

Iyer LM, Nagarajan S, Woelfer M, Schoger E, Khadjeh S, Zafiriou MP, Kari V, Herting J, Pang ST, Weber T, Rathjens FS, Fischer TH, Toischer K, Hasenfuss G, Noack C, Johnsen SA, Zelarayán LC.

Nucleic Acids Res. 2018 Apr 6;46(6):2850-2867. doi: 10.1093/nar/gky049.

10.

Genetic Origins of Tetralogy of Fallot.

Morgenthau A, Frishman WH.

Cardiol Rev. 2018 Mar/Apr;26(2):86-92. doi: 10.1097/CRD.0000000000000170.

PMID:
29045289
11.

Aryl Hydrocarbon Receptor Ablation in Cardiomyocytes Protects Male Mice From Heart Dysfunction Induced by NKX2.5 Haploinsufficiency.

Wang Q, Fan Y, Kurita H, Jiang M, Koch S, Rao MB, Rubinstein J, Puga A.

Toxicol Sci. 2017 Nov 1;160(1):74-82. doi: 10.1093/toxsci/kfx164.

PMID:
28973413
12.

RHOA-ROCK signalling is necessary for lateralization and differentiation of the developing sinoatrial node.

Vicente-Steijn R, Kelder TP, Tertoolen LG, Wisse LJ, Pijnappels DA, Poelmann RE, Schalij MJ, deRuiter MC, Gittenberger-de Groot AC, Jongbloed MRM.

Cardiovasc Res. 2017 Aug 1;113(10):1186-1197. doi: 10.1093/cvr/cvx104.

PMID:
28899000
13.

Targeting miR-423-5p Reverses Exercise Training-Induced HCN4 Channel Remodeling and Sinus Bradycardia.

D'Souza A, Pearman CM, Wang Y, Nakao S, Logantha SJRJ, Cox C, Bennett H, Zhang Y, Johnsen AB, Linscheid N, Poulsen PC, Elliott J, Coulson J, McPhee J, Robertson A, da Costa Martins PA, Kitmitto A, Wisløff U, Cartwright EJ, Monfredi O, Lundby A, Dobrzynski H, Oceandy D, Morris GM, Boyett MR.

Circ Res. 2017 Oct 13;121(9):1058-1068. doi: 10.1161/CIRCRESAHA.117.311607. Epub 2017 Aug 17.

14.

Activation of the Nkx2.5-Calr-p53 signaling pathway by hyperglycemia induces cardiac remodeling and dysfunction in adult zebrafish.

Sun Y, Wang Q, Fang Y, Wu C, Lu G, Chen Z.

Dis Model Mech. 2017 Oct 1;10(10):1217-1227. doi: 10.1242/dmm.026781. Epub 2017 Aug 11.

15.
16.

Prevalence and Spectrum of NKX2-5 Mutations Associated With Sporadic Adult-Onset Dilated Cardiomyopathy.

Xu JH, Gu JY, Guo YH, Zhang H, Qiu XB, Li RG, Shi HY, Liu H, Yang XX, Xu YJ, Qu XK, Yang YQ.

Int Heart J. 2017 Aug 3;58(4):521-529. doi: 10.1536/ihj.16-440. Epub 2017 Jul 10.

17.

Transient Notch Activation Induces Long-Term Gene Expression Changes Leading to Sick Sinus Syndrome in Mice.

Qiao Y, Lipovsky C, Hicks S, Bhatnagar S, Li G, Khandekar A, Guzy R, Woo KV, Nichols CG, Efimov IR, Rentschler S.

Circ Res. 2017 Aug 18;121(5):549-563. doi: 10.1161/CIRCRESAHA.116.310396. Epub 2017 Jul 3.

18.

Generation of Nkx2-5/CreER transgenic mice for inducible Cre expression in developing hearts.

Ranjbarvaziri S, Park S, Nguyen NB, Gilmore WB, Zhao P, Ardehali R.

Genesis. 2017 Aug;55(8). doi: 10.1002/dvg.23041. Epub 2017 Jun 15.

19.

β-Cyclodextrin induces the differentiation of resident cardiac stem cells to cardiomyocytes through autophagy.

Shi X, Li W, Liu H, Yin D, Zhao J.

Biochim Biophys Acta. 2017 Aug;1864(8):1425-1434. doi: 10.1016/j.bbamcr.2017.05.012. Epub 2017 May 15.

20.

Point mutations in murine Nkx2-5 phenocopy human congenital heart disease and induce pathogenic Wnt signaling.

Furtado MB, Wilmanns JC, Chandran A, Perera J, Hon O, Biben C, Willow TJ, Nim HT, Kaur G, Simonds S, Wu Q, Willians D, Salimova E, Plachta N, Denegre JM, Murray SA, Fatkin D, Cowley M, Pearson JT, Kaye D, Ramialison M, Harvey RP, Rosenthal NA, Costa MW.

JCI Insight. 2017 Mar 23;2(6):e88271. doi: 10.1172/jci.insight.88271.

Supplemental Content

Loading ...
Support Center