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Items: 1 to 20 of 233

1.

The Therapeutic Potential of Nanobodies.

Jovčevska I, Muyldermans S.

BioDrugs. 2019 Nov 4. doi: 10.1007/s40259-019-00392-z. [Epub ahead of print] Review.

PMID:
31686399
2.

Development of anti-matrix metalloproteinase-2 (MMP-2) nanobodies as potential therapeutic and diagnostic tools.

Marturano A, Hendrickx MLV, Falcinelli E, Sebastiano M, Guglielmini G, Hassanzadeh-Ghassabeh G, Muyldermans S, Declerck PJ, Gresele P.

Nanomedicine. 2019 Oct 24;24:102103. doi: 10.1016/j.nano.2019.102103. [Epub ahead of print]

PMID:
31669421
3.

Increased Expression of Adherens Junction Components in Mouse Liver following Bile Duct Ligation.

Van Campenhout R, Crespo Yanguas S, Cooreman A, Gijbels E, Leroy K, Vilas-Boas V, Devoogdt N, Muyldermans S, Cogliati B, Vinken M.

Biomolecules. 2019 Oct 22;9(10). pii: E636. doi: 10.3390/biom9100636.

4.

Identification of New DR5 Agonistic Nanobodies and Generation of Multivalent Nanobody Constructs for Cancer Treatment.

Sadeghnezhad G, Romão E, Bernedo-Navarro R, Massa S, Khajeh K, Muyldermans S, Hassania S.

Int J Mol Sci. 2019 Sep 27;20(19). pii: E4818. doi: 10.3390/ijms20194818.

5.

Development of a mono-specific anti-VEGF bivalent nanobody with extended plasma half-life for treatment of pathologic neovascularization.

Sadeghi A, Behdani M, Muyldermans S, Habibi-Anbouhi M, Kazemi-Lomedasht F.

Drug Test Anal. 2019 Sep 2. doi: 10.1002/dta.2693. [Epub ahead of print]

PMID:
31476257
6.

Fast One-Step Ultrasensitive Detection of Toxocara canis Antigens by a Nanobody-Based Electrochemical Magnetosensor.

Morales-Yánez F, Trashin S, Hermy M, Sariego I, Polman K, Muyldermans S, De Wael K.

Anal Chem. 2019 Sep 17;91(18):11582-11588. doi: 10.1021/acs.analchem.9b01687. Epub 2019 Aug 30.

PMID:
31429269
7.

Soluble aggregates present in cerebrospinal fluid change in size and mechanism of toxicity during Alzheimer's disease progression.

De S, Whiten DR, Ruggeri FS, Hughes C, Rodrigues M, Sideris DI, Taylor CG, Aprile FA, Muyldermans S, Knowles TPJ, Vendruscolo M, Bryant C, Blennow K, Skoog I, Kern S, Zetterberg H, Klenerman D.

Acta Neuropathol Commun. 2019 Jul 26;7(1):120. doi: 10.1186/s40478-019-0777-4.

8.

Site-Selective Functionalization of Nanobodies Using Intein-Mediated Protein Ligation for Innovative Bioconjugation.

Graulus GJ, Ta DT, Tran H, Hansen R, Billen B, Royackers E, Noben JP, Devoogdt N, Muyldermans S, Guedens W, Adriaensens P.

Methods Mol Biol. 2019;2033:117-130. doi: 10.1007/978-1-4939-9654-4_9.

PMID:
31332751
9.

NIRF-Molecular Imaging with Synovial Macrophages-Targeting Vsig4 Nanobody for Disease Monitoring in a Mouse Model of Arthritis.

Zheng F, Luo S, Ouyang Z, Zhou J, Mo H, Schoonooghe S, Muyldermans S, De Baetselier P, Raes G, Wen Y.

Int J Mol Sci. 2019 Jul 8;20(13). pii: E3347. doi: 10.3390/ijms20133347.

10.

An innovative approach in the detection of Toxocara canis excretory/secretory antigens using specific nanobodies.

Morales-Yanez FJ, Sariego I, Vincke C, Hassanzadeh-Ghassabeh G, Polman K, Muyldermans S.

Int J Parasitol. 2019 Jul;49(8):635-645. doi: 10.1016/j.ijpara.2019.03.004. Epub 2019 May 29.

11.

Llama peripheral B-cell populations producing conventional and heavy chain-only IgG subtypes are phenotypically indistinguishable but immunogenetically distinct.

Henry KA, van Faassen H, Harcus D, Marcil A, Hill JJ, Muyldermans S, MacKenzie CR.

Immunogenetics. 2019 Apr;71(4):307-320. doi: 10.1007/s00251-018-01102-9. Epub 2019 Jan 18.

PMID:
30656359
12.

Understanding the Significance and Implications of Antibody Numbering and Antigen-Binding Surface/Residue Definition.

Dondelinger M, Filée P, Sauvage E, Quinting B, Muyldermans S, Galleni M, Vandevenne MS.

Front Immunol. 2018 Oct 16;9:2278. doi: 10.3389/fimmu.2018.02278. eCollection 2018. Review.

13.

Guided Evolution of Recombinant Bombyx mori Acetylcholinesterase II by Homology Modeling to Change Pesticide Sensitivity.

Cai J, Wang B, Li J, Chen Z, Rao M, Muyldermans S, Hua X, Xie X, Wang H, Yang J, Xu Z, Shen Y, Sun Y.

Int J Mol Sci. 2018 Oct 27;19(11). pii: E3366. doi: 10.3390/ijms19113366.

14.

The Development and Validation of a Novel Nanobody-Based Competitive ELISA for the Detection of Foot and Mouth Disease 3ABC Antibodies in Cattle.

Gelkop S, Sobarzo A, Brangel P, Vincke C, Romão E, Fedida-Metula S, Strom N, Ataliba I, Mwiine FN, Ochwo S, Velazquez-Salinas L, McKendry RA, Muyldermans S, Lutwama JJ, Rieder E, Yavelsky V, Lobel L.

Front Vet Sci. 2018 Oct 12;5:250. doi: 10.3389/fvets.2018.00250. eCollection 2018.

15.

Nanobodies as novel therapeutic agents in envenomation.

Alirahimi E, Kazemi-Lomedasht F, Shahbazzadeh D, Habibi-Anbouhi M, Hosseininejad Chafi M, Sotoudeh N, Ghaderi H, Muyldermans S, Behdani M.

Biochim Biophys Acta Gen Subj. 2018 Dec;1862(12):2955-2965. doi: 10.1016/j.bbagen.2018.08.019. Epub 2018 Aug 30. Review.

PMID:
30309831
16.

Site-Specific Radioactive Labeling of Nanobodies.

Crauwels M, Massa S, Martin C, Betti C, Ballet S, Devoogdt N, Xavier C, Muyldermans S.

Methods Mol Biol. 2018;1827:505-540. doi: 10.1007/978-1-4939-8648-4_26.

PMID:
30196514
17.

Blocking EGFR Activation with Anti-EGF Nanobodies via Two Distinct Molecular Recognition Mechanisms.

Guardiola S, Varese M, Sánchez-Navarro M, Vincke C, Teixidó M, García J, Muyldermans S, Giralt E.

Angew Chem Int Ed Engl. 2018 Oct 15;57(42):13843-13847. doi: 10.1002/anie.201807736. Epub 2018 Sep 21.

PMID:
30152597
18.

Development of a Nanobody-based lateral flow assay to detect active Trypanosoma congolense infections.

Pinto Torres JE, Goossens J, Ding J, Li Z, Lu S, Vertommen D, Naniima P, Chen R, Muyldermans S, Sterckx YG, Magez S.

Sci Rep. 2018 Jun 13;8(1):9019. doi: 10.1038/s41598-018-26732-7.

19.

The structural basis of nanobody unfolding reversibility and thermoresistance.

Kunz P, Zinner K, Mücke N, Bartoschik T, Muyldermans S, Hoheisel JD.

Sci Rep. 2018 May 21;8(1):7934. doi: 10.1038/s41598-018-26338-z.

20.

Glioblastoma-specific anti-TUFM nanobody for in-vitro immunoimaging and cancer stem cell targeting.

Samec N, Jovcevska I, Stojan J, Zottel A, Liovic M, Myers MP, Muyldermans S, Šribar J, Križaj I, Komel R.

Oncotarget. 2018 Apr 3;9(25):17282-17299. doi: 10.18632/oncotarget.24629. eCollection 2018 Apr 3.

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