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The impact of treatment with avacopan on health-related quality of life in antineutrophil cytoplasmic antibody-associated vasculitis: a post-hoc analysis of data from the ADVOCATE trial.
Strand V, Jayne DRW, Horomanski A, Yue H, Bekker P, Merkel PA; ADVOCATE Study Group. Strand V, et al. Lancet Rheumatol. 2023 Aug;5(8):e451-e460. doi: 10.1016/S2665-9913(23)00092-9. Epub 2023 Jul 24. Lancet Rheumatol. 2023. PMID: 38251577 Clinical Trial.
We analysed summary scores and individual domain scores for the prespecified health-related quality of life outcomes from ADVOCATE, which were evaluated at weeks 26 and 52 by use of the Medical Outcomes Survey 36-Item Short Form Health Survey (SF-36) version 2, the EuroQol 5-Dime …
We analysed summary scores and individual domain scores for the prespecified health-related quality of life outcomes from ADVOCATE, which we …
An external pilot cluster randomised controlled trial of a theory-based intervention to improve appropriate polypharmacy in older people in primary care (PolyPrime).
Rankin A, Gorman A, Cole J, Cadogan CA, Barry HE, Agus A, Logan D, McDowell C, Molloy GJ, Ryan C, Leathem C, Maxwell M, Brennan C, Gormley GJ, Ferrett A, McCarthy P, Fahey T, Hughes CM; PolyPrime team. Rankin A, et al. Pilot Feasibility Stud. 2022 Sep 10;8(1):203. doi: 10.1186/s40814-022-01161-6. Pilot Feasibility Stud. 2022. PMID: 36088445 Free PMC article.
HRQoL was measured using the EuroQol-5 dimension-5 level questionnaire (EQ-5D-5L) and medication-related burden quality-of-life (MRB-QoL) tool. ...GP record data were available for 47 patients for medication appropriateness analysis at 9 months. EQ-5D-5L and MRB-QoL …
HRQoL was measured using the EuroQol-5 dimension-5 level questionnaire (EQ-5D-5L) and medication-related burden quality-of-life (MRB- …
360-Degree Complex Primary Reconstruction Using Porous Tantalum Cages for Adult Degenerative Spinal Deformity.
Butler JS, Lui DF, Malhotra K, Suarez-Huerta ML, Yu H, Selvadurai S, Agu O, Molloy S. Butler JS, et al. Global Spine J. 2019 Sep;9(6):613-618. doi: 10.1177/2192568218814531. Epub 2018 Nov 21. Global Spine J. 2019. PMID: 31448194 Free PMC article.
The mean Oswestry Disability Index improved from 69.5 21.5 preoperatively to 19.9 15.2 at 2 years (P < .001). The EQ-5D mean score improved from 0.2 0.2 preoperatively to 0.8 0.1 at 2 years (P = .02). ...

The mean Oswestry Disability Index improved from 69.5 21.5 preoperatively to 19.9 15.2 at 2 years (P < .001). The EQ-5D mean score

…
Prevalence of inflammatory back pain in a cohort of patients with anterior uveitis.
Chan CC, Inrig T, Molloy CB, Stone MA, Derzko-Dzulynsky L. Chan CC, et al. Am J Ophthalmol. 2012 Jun;153(6):1025-30.e1. doi: 10.1016/j.ajo.2011.11.016. Epub 2012 Feb 8. Am J Ophthalmol. 2012. PMID: 22321801
The impact of disease on quality of life was measured using the EuroQOL (EQ-5D) questionnaire. Twenty-five patients underwent further rheumatologic examination. ...Sixty-six of 141 patients (46.8%) were classified to have inflammatory back pain. Mean BASDAI (4.2, SD 2.41) …
The impact of disease on quality of life was measured using the EuroQOL (EQ-5D) questionnaire. Twenty-five patients underwent further …
Cost-Utility Analysis of Total Ankle Replacement Compared with Ankle Arthrodesis for Patients Aged 50-85 Years with End-Stage Ankle Osteoarthritis: The TARVA Study.
Goldberg AJ, Bordea E, Chowdhury K, Hauptmannova I, Blackstone J, Brooking D, Deane EL, Bendall S, Bing A, Blundell C, Dhar S, Molloy A, Milner S, Karski M, Hepple S, Siddique M, Loveday DT, Mishra V, Cooke P, Halliwell P, Townshend D, Skene SS, Doré CJ; TARVA Study Group. Goldberg AJ, et al. Pharmacoecon Open. 2024 Mar;8(2):235-249. doi: 10.1007/s41669-023-00449-4. Epub 2024 Jan 8. Pharmacoecon Open. 2024. PMID: 38189868 Free PMC article.
METHOD: We conducted a cost-utility analysis of 282 participants from 17 UK centres recruited to a randomised controlled trial (TARVA). QALYs were calculated using index values from EQ-5D-5L. Resource use information was collected from case report forms and self-completed …
METHOD: We conducted a cost-utility analysis of 282 participants from 17 UK centres recruited to a randomised controlled trial (TARVA). QALY …
Physiotherapy and Occupational Therapy vs No Therapy in Mild to Moderate Parkinson Disease: A Randomized Clinical Trial.
Clarke CE, Patel S, Ives N, Rick CE, Dowling F, Woolley R, Wheatley K, Walker MF, Sackley CM; PD REHAB Collaborative Group. Clarke CE, et al. JAMA Neurol. 2016 Mar;73(3):291-9. doi: 10.1001/jamaneurol.2015.4452. JAMA Neurol. 2016. PMID: 26785394 Clinical Trial.
Secondary outcomes were health-related quality of life (assessed by Parkinson Disease Questionnaire-39 and EuroQol-5D); adverse events; and caregiver quality of life. Outcomes were assessed before trial entry and then 3, 9, and 15 months after randomization. ...Repeated-me …
Secondary outcomes were health-related quality of life (assessed by Parkinson Disease Questionnaire-39 and EuroQol-5D); adverse event …
A new extensile anterolateral retroperitoneal approach for lumbar interbody fusion from L1 to S1: a prospective series with clinical outcomes.
Molloy S, Butler JS, Benton A, Malhotra K, Selvadurai S, Agu O. Molloy S, et al. Spine J. 2016 Jun;16(6):786-91. doi: 10.1016/j.spinee.2016.03.044. Epub 2016 Mar 23. Spine J. 2016. PMID: 27033312
Clinical outcome measures used included visual analogue scale (VAS) Back Pain, VAS Leg Pain, EuroQoL-5 Dimensions (EQ-5D), EQ-5D VAS, Oswestry Disability Index (ODI), and Scoliosis Research Society-22 (SRS-22). ...
Clinical outcome measures used included visual analogue scale (VAS) Back Pain, VAS Leg Pain, EuroQoL-5 Dimensions (EQ-5D), EQ-5D …
Pathologic sternal involvement is a potential risk factor for severe sagittal plane deformity in multiple myeloma with concomitant thoracic fractures.
Butler JS, Malhotra K, Patel A, Sewell MD, Benton A, Kyriakou C, Molloy S. Butler JS, et al. Spine J. 2015 Dec 1;15(12):2503-8. doi: 10.1016/j.spinee.2015.09.031. Epub 2015 Sep 25. Spine J. 2015. PMID: 26407504
OUTCOME MEASURES: Clinical outcome measures used included European Quality of Life-5 Dimensions (EQ-5D), Oswestry Disability Index (ODI), and visual analogue scale (VAS) pain score. ...The SF group presented with a greater thoracic kyphosis (7318 vs. 5317.5 [p=.005]), simi …
OUTCOME MEASURES: Clinical outcome measures used included European Quality of Life-5 Dimensions (EQ-5D), Oswestry Disability Index (O …
A multicentre, randomised controlled trial to compare the clinical and cost-effectiveness of Lee Silverman Voice Treatment versus standard NHS Speech and Language Therapy versus control in Parkinson's disease: a study protocol for a randomised controlled trial.
Sackley CM, Rick C, Au P, Brady MC, Beaton G, Burton C, Caulfield M, Dickson S, Dowling F, Hughes M, Ives N, Jowett S, Masterson-Algar P, Nicoll A, Patel S, Smith CH, Woolley R, Clarke CE; PD COMM Collaborative Group. Sackley CM, et al. Trials. 2020 May 27;21(1):436. doi: 10.1186/s13063-020-04354-7. Trials. 2020. PMID: 32460885 Free PMC article.
Secondary outcomes include: VHI subscales, Parkinson's Disease Questionnaire-39; Questionnaire on Acquired Speech Disorders; EuroQol-5D-5 L; ICECAP-O; resource utilisation; adverse events and carer quality of life. ...
Secondary outcomes include: VHI subscales, Parkinson's Disease Questionnaire-39; Questionnaire on Acquired Speech Disorders; EuroQol-5D …
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