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Items: 1 to 20 of 230


Ostreolysin A/Pleurotolysin B and Equinatoxins: Structure, Function and Pathophysiological Effects of These Pore-Forming Proteins.

Frangež R, Šuput D, Molgó J, Benoit E.

Toxins (Basel). 2017 Apr 5;9(4). pii: E128. doi: 10.3390/toxins9040128. Review.


Cyclic imine toxins from dinoflagellates: a growing family of potent antagonists of the nicotinic acetylcholine receptors.

Molgó J, Marchot P, Aráoz R, Benoit E, Iorga BI, Zakarian A, Taylor P, Bourne Y, Servent D.

J Neurochem. 2017 Mar 21. doi: 10.1111/jnc.13995. [Epub ahead of print] Review.


The Dinoflagellate Toxin 20-Methyl Spirolide-G Potently Blocks Skeletal Muscle and Neuronal Nicotinic Acetylcholine Receptors.

Couesnon A, Aráoz R, Iorga BI, Benoit E, Reynaud M, Servent D, Molgó J.

Toxins (Basel). 2016 Aug 24;8(9). pii: E249. doi: 10.3390/toxins8090249.


Selective Vulnerability of Cancer Cells by Inhibition of Ca(2+) Transfer from Endoplasmic Reticulum to Mitochondria.

Cárdenas C, Müller M, McNeal A, Lovy A, Jaňa F, Bustos G, Urra F, Smith N, Molgó J, Diehl JA, Ridky TW, Foskett JK.

Cell Rep. 2016 Apr 5;15(1):219-20. doi: 10.1016/j.celrep.2016.03.045. No abstract available.


Special Issue on "Toxins: New targets and new functions".

Benoit E, Barbier J, Popoff MR, Faure G, Molgó J, Servent D.

Toxicon. 2016 Jun 15;116:1-3. doi: 10.1016/j.toxicon.2016.03.012. Epub 2016 Mar 17. No abstract available.


Neuromuscular junction immaturity and muscle atrophy are hallmarks of the ColQ-deficient mouse, a model of congenital myasthenic syndrome with acetylcholinesterase deficiency.

Sigoillot SM, Bourgeois F, Karmouch J, Molgó J, Dobbertin A, Chevalier C, Houlgatte R, Léger J, Legay C.

FASEB J. 2016 Jun;30(6):2382-99. doi: 10.1096/fj.201500162. Epub 2016 Mar 18.


Selective Vulnerability of Cancer Cells by Inhibition of Ca(2+) Transfer from Endoplasmic Reticulum to Mitochondria.

Cárdenas C, Müller M, McNeal A, Lovy A, Jaňa F, Bustos G, Urra F, Smith N, Molgó J, Diehl JA, Ridky TW, Foskett JK.

Cell Rep. 2016 Mar 15;14(10):2313-24. doi: 10.1016/j.celrep.2016.02.030. Epub 2016 Mar 3. Erratum in: Cell Rep. 2016 Apr 5;15(1):219-20.


Epithelial-mesenchymal transition, IP3 receptors and ER-PM junctions: translocation of Ca2+ signalling complexes and regulation of migration.

Okeke E, Parker T, Dingsdale H, Concannon M, Awais M, Voronina S, Molgó J, Begg M, Metcalf D, Knight AE, Sutton R, Haynes L, Tepikin AV.

Biochem J. 2016 Mar 15;473(6):757-67. doi: 10.1042/BJ20150364. Epub 2016 Jan 12.


Sympathetic innervation controls homeostasis of neuromuscular junctions in health and disease.

Khan MM, Lustrino D, Silveira WA, Wild F, Straka T, Issop Y, O'Connor E, Cox D, Reischl M, Marquardt T, Labeit D, Labeit S, Benoit E, Molgó J, Lochmüller H, Witzemann V, Kettelhut IC, Navegantes LC, Pozzan T, Rudolf R.

Proc Natl Acad Sci U S A. 2016 Jan 19;113(3):746-50. doi: 10.1073/pnas.1524272113. Epub 2016 Jan 5. Erratum in: Proc Natl Acad Sci U S A. 2017 Jun 19;:.


HERPUD1 protects against oxidative stress-induced apoptosis through downregulation of the inositol 1,4,5-trisphosphate receptor.

Paredes F, Parra V, Torrealba N, Navarro-Marquez M, Gatica D, Bravo-Sagua R, Troncoso R, Pennanen C, Quiroga C, Chiong M, Caesar C, Taylor WR, Molgó J, San Martin A, Jaimovich E, Lavandero S.

Free Radic Biol Med. 2016 Jan;90:206-18. doi: 10.1016/j.freeradbiomed.2015.11.024. Epub 2015 Nov 23.


Translocation and dissemination to target neurons of botulinum neurotoxin type B in the mouse intestinal wall.

Connan C, Varela-Chavez C, Mazuet C, Molgó J, Haustant GM, Disson O, Lecuit M, Vandewalle A, Popoff MR.

Cell Microbiol. 2016 Feb;18(2):282-301. doi: 10.1111/cmi.12502. Epub 2015 Sep 18.


MCUR1 is an essential component of mitochondrial Ca(2+) uptake that regulates cellular metabolism.

Mallilankaraman K, Cárdenas C, Doonan PJ, Chandramoorthy HC, Irrinki KM, Golenár T, Csordás G, Madireddi P, Yang J, Müller M, Miller R, Kolesar JE, Molgó J, Kaufman B, Hajnóczky G, Foskett JK, Madesh M.

Nat Cell Biol. 2015 Jul;17(7):953. doi: 10.1038/ncb3202. No abstract available.


The Neurotoxic Effect of 13,19-Didesmethyl and 13-Desmethyl Spirolide C Phycotoxins Is Mainly Mediated by Nicotinic Rather Than Muscarinic Acetylcholine Receptors.

Aráoz R, Ouanounou G, Iorga BI, Goudet A, Alili D, Amar M, Benoit E, Molgó J, Servent D.

Toxicol Sci. 2015 Sep;147(1):156-67. doi: 10.1093/toxsci/kfv119. Epub 2015 Jun 10.


Marine Macrocyclic Imines, Pinnatoxins A and G: Structural Determinants and Functional Properties to Distinguish Neuronal α7 from Muscle α1(2)βγδ nAChRs.

Bourne Y, Sulzenbacher G, Radić Z, Aráoz R, Reynaud M, Benoit E, Zakarian A, Servent D, Molgó J, Taylor P, Marchot P.

Structure. 2015 Jun 2;23(6):1106-15. doi: 10.1016/j.str.2015.04.009. Epub 2015 May 21.


MuSK frizzled-like domain is critical for mammalian neuromuscular junction formation and maintenance.

Messéant J, Dobbertin A, Girard E, Delers P, Manuel M, Mangione F, Schmitt A, Le Denmat D, Molgó J, Zytnicki D, Schaeffer L, Legay C, Strochlic L.

J Neurosci. 2015 Mar 25;35(12):4926-41. doi: 10.1523/JNEUROSCI.3381-14.2015.


Endoplasmic reticulum Ca(2+) content decrease by PKA-dependent hyperphosphorylation of type 1 IP3 receptor contributes to prostate cancer cell resistance to androgen deprivation.

Boutin B, Tajeddine N, Monaco G, Molgo J, Vertommen D, Rider M, Parys JB, Bultynck G, Gailly P.

Cell Calcium. 2015 Apr;57(4):312-20. doi: 10.1016/j.ceca.2015.02.004. Epub 2015 Feb 18.


Ryanodine and inositol triphosphate receptors modulate facilitation and tetanic depression at the frog neuromuscular junction.

Silveira PE, Lima RF, Guimarães JD, Molgó J, Naves LA, Kushmerick C.

Muscle Nerve. 2015 Oct;52(4):623-30. doi: 10.1002/mus.24571. Epub 2015 Jul 2.


Special Issue on "freshwater and marine toxins".

Benoit E, Mattei C, Barbier J, Marchot P, Molgó J, Servent D.

Toxicon. 2014 Dec;91:1-4. doi: 10.1016/j.toxicon.2014.11.217. Epub 2014 Nov 20. No abstract available.


Isolation, purification and functional characterization of alpha-BnIA from Conus bandanus venom.

Nguyen B, Le Caer JP, Aráoz R, Thai R, Lamthanh H, Benoit E, Molgó J.

Toxicon. 2014 Dec;91:155-63. doi: 10.1016/j.toxicon.2014.10.006. Epub 2014 Oct 15.


Synthesis and biology of cyclic imine toxins, an emerging class of potent, globally distributed marine toxins.

Stivala CE, Benoit E, Aráoz R, Servent D, Novikov A, Molgó J, Zakarian A.

Nat Prod Rep. 2015 Mar;32(3):411-35. doi: 10.1039/c4np00089g. Review.

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