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Items: 1 to 20 of 103

1.

Additional Candidate Genes for Human Atherosclerotic Disease Identified Through Annotation Based on Chromatin Organization.

Haitjema S, Meddens CA, van der Laan SW, Kofink D, Harakalova M, Tragante V, Foroughi Asl H, van Setten J, Brandt MM, Bis JC, O'Donnell C, Cheng C, Hoefer IE, Waltenberger J, Biessen E, Jukema JW, Doevendans PA, Nieuwenhuis EE, Erdmann J, Björkegren JL, Pasterkamp G, Asselbergs FW, den Ruijter HM, Mokry M.

Circ Cardiovasc Genet. 2017 Apr;10(2). pii: e001664. doi: 10.1161/CIRCGENETICS.116.001664.

PMID:
28320757
2.

Systematic analysis of chromatin interactions at disease associated loci links novel candidate genes to inflammatory bowel disease.

Meddens CA, Harakalova M, van den Dungen NA, Foroughi Asl H, Hijma HJ, Cuppen EP, Björkegren JL, Asselbergs FW, Nieuwenhuis EE, Mokry M.

Genome Biol. 2016 Nov 30;17(1):247.

3.

Extensive Association of Common Disease Variants with Regulatory Sequence.

Mokry M, Harakalova M, Asselbergs FW, de Bakker PI, Nieuwenhuis EE.

PLoS One. 2016 Nov 22;11(11):e0165893. doi: 10.1371/journal.pone.0165893. eCollection 2016.

4.

A piezoelectric device for bone work in endoscopic anterior skull base surgery - a feasibility study in 15 patients.

Gellner V, Koele W, Wolf A, Gerstenberger C, Mokry M, Stammberger H, Tomazic PV.

Clin Otolaryngol. 2016 Oct 3. doi: 10.1111/coa.12760. [Epub ahead of print] No abstract available.

PMID:
27696757
5.

Tissue-specific mutation accumulation in human adult stem cells during life.

Blokzijl F, de Ligt J, Jager M, Sasselli V, Roerink S, Sasaki N, Huch M, Boymans S, Kuijk E, Prins P, Nijman IJ, Martincorena I, Mokry M, Wiegerinck CL, Middendorp S, Sato T, Schwank G, Nieuwenhuis EE, Verstegen MM, van der Laan LJ, de Jonge J, IJzermans JN, Vries RG, van de Wetering M, Stratton MR, Clevers H, Cuppen E, van Boxtel R.

Nature. 2016 Oct 13;538(7624):260-264. doi: 10.1038/nature19768. Epub 2016 Oct 3.

PMID:
27698416
6.

An siRNA screen for ATG protein depletion reveals the extent of the unconventional functions of the autophagy proteome in virus replication.

Mauthe M, Langereis M, Jung J, Zhou X, Jones A, Omta W, Tooze SA, Stork B, Paludan SR, Ahola T, Egan D, Behrends C, Mokry M, de Haan C, van Kuppeveld F, Reggiori F.

J Cell Biol. 2016 Aug 29;214(5):619-35. doi: 10.1083/jcb.201602046.

7.

E2f8 mediates tumor suppression in postnatal liver development.

Kent LN, Rakijas JB, Pandit SK, Westendorp B, Chen HZ, Huntington JT, Tang X, Bae S, Srivastava A, Senapati S, Koivisto C, Martin CK, Cuitino MC, Perez M, Clouse JM, Chokshi V, Shinde N, Kladney R, Sun D, Perez-Castro A, Matondo RB, Nantasanti S, Mokry M, Huang K, Machiraju R, Fernandez S, Rosol TJ, Coppola V, Pohar KS, Pipas JM, Schmidt CR, de Bruin A, Leone G.

J Clin Invest. 2016 Aug 1;126(8):2955-69. doi: 10.1172/JCI85506. Epub 2016 Jul 25.

8.

Enhancers reside in a unique epigenetic environment during early zebrafish development.

Kaaij LJ, Mokry M, Zhou M, Musheev M, Geeven G, Melquiond AS, de Jesus Domingues AM, de Laat W, Niehrs C, Smith AD, Ketting RF.

Genome Biol. 2016 Jul 5;17(1):146. doi: 10.1186/s13059-016-1013-1.

9.

Establishment of clival chordoma cell line MUG-CC1 and lymphoblastoid cells as a model for potential new treatment strategies.

Gellner V, Tomazic PV, Lohberger B, Meditz K, Heitzer E, Mokry M, Koele W, Leithner A, Liegl-Atzwanger B, Rinner B.

Sci Rep. 2016 Apr 13;6:24195. doi: 10.1038/srep24195.

10.

Autoimmune disease-associated gene expression is reduced by BET-inhibition.

Peeters JG, Vervoort SJ, Mijnheer G, de Roock S, Vastert SJ, Nieuwenhuis EE, van Wijk F, Prakken BJ, Mokry M, van Loosdregt J.

Genom Data. 2015 Nov 7;7:14-7. doi: 10.1016/j.gdata.2015.11.004. eCollection 2016 Mar.

11.

Neonatal thymectomy reveals differentiation and plasticity within human naive T cells.

van den Broek T, Delemarre EM, Janssen WJ, Nievelstein RA, Broen JC, Tesselaar K, Borghans JA, Nieuwenhuis EE, Prakken BJ, Mokry M, Jansen NJ, van Wijk F.

J Clin Invest. 2016 Mar 1;126(3):1126-36. doi: 10.1172/JCI84997. Epub 2016 Feb 22.

12.

Gene expression profiling in human precision cut liver slices in response to the FXR agonist obeticholic acid.

Ijssennagger N, Janssen AW, Milona A, Ramos Pittol JM, Hollman DA, Mokry M, Betzel B, Berends FJ, Janssen IM, van Mil SW, Kersten S.

J Hepatol. 2016 May;64(5):1158-66. doi: 10.1016/j.jhep.2016.01.016. Epub 2016 Jan 23.

PMID:
26812075
13.

FOXP3 can modulate TAL1 transcriptional activity through interaction with LMO2.

Fleskens V, Mokry M, van der Leun AM, Huppelschoten S, Pals CE, Peeters J, Coenen S, Cardoso BA, Barata JT, van Loosdregt J, Coffer PJ.

Oncogene. 2016 Aug 4;35(31):4141-8. doi: 10.1038/onc.2015.481. Epub 2015 Dec 21.

PMID:
26686090
14.

Genome-wide analysis reveals NRP1 as a direct HIF1α-E2F7 target in the regulation of motorneuron guidance in vivo.

de Bruin A, A Cornelissen PW, Kirchmaier BC, Mokry M, Iich E, Nirmala E, Liang KH, D Végh AM, Scholman KT, Groot Koerkamp MJ, Holstege FC, Cuppen E, Schulte-Merker S, Bakker WJ.

Nucleic Acids Res. 2016 May 5;44(8):3549-66. doi: 10.1093/nar/gkv1471. Epub 2015 Dec 17.

15.

Interleukin-22 promotes intestinal-stem-cell-mediated epithelial regeneration.

Lindemans CA, Calafiore M, Mertelsmann AM, O'Connor MH, Dudakov JA, Jenq RR, Velardi E, Young LF, Smith OM, Lawrence G, Ivanov JA, Fu YY, Takashima S, Hua G, Martin ML, O'Rourke KP, Lo YH, Mokry M, Romera-Hernandez M, Cupedo T, Dow LE, Nieuwenhuis EE, Shroyer NF, Liu C, Kolesnick R, van den Brink MR, Hanash AM.

Nature. 2015 Dec 24;528(7583):560-4. doi: 10.1038/nature16460. Epub 2015 Dec 9.

16.

Inhibition of Super-Enhancer Activity in Autoinflammatory Site-Derived T Cells Reduces Disease-Associated Gene Expression.

Peeters JG, Vervoort SJ, Tan SC, Mijnheer G, de Roock S, Vastert SJ, Nieuwenhuis EE, van Wijk F, Prakken BJ, Creyghton MP, Coffer PJ, Mokry M, van Loosdregt J.

Cell Rep. 2015 Sep 29;12(12):1986-96. doi: 10.1016/j.celrep.2015.08.046. Epub 2015 Sep 17.

17.

The forkhead transcription factor FOXP1 represses human plasma cell differentiation.

van Keimpema M, Grüneberg LJ, Mokry M, van Boxtel R, van Zelm MC, Coffer P, Pals ST, Spaargaren M.

Blood. 2015 Oct 29;126(18):2098-109. doi: 10.1182/blood-2015-02-626176. Epub 2015 Aug 19.

18.

A systematic analysis of genetic dilated cardiomyopathy reveals numerous ubiquitously expressed and muscle-specific genes.

Harakalova M, Kummeling G, Sammani A, Linschoten M, Baas AF, van der Smagt J, Doevendans PA, van Tintelen JP, Dooijes D, Mokry M, Asselbergs FW.

Eur J Heart Fail. 2015 May;17(5):484-93. doi: 10.1002/ejhf.255. Epub 2015 Mar 2.

19.

Rare case of a primary intracranial chondrosarcoma.

Smolle E, Mokry M, Haybaeck J.

Anticancer Res. 2015 Feb;35(2):875-80.

PMID:
25667469
20.

Ascl2 acts as an R-spondin/Wnt-responsive switch to control stemness in intestinal crypts.

Schuijers J, Junker JP, Mokry M, Hatzis P, Koo BK, Sasselli V, van der Flier LG, Cuppen E, van Oudenaarden A, Clevers H.

Cell Stem Cell. 2015 Feb 5;16(2):158-70. doi: 10.1016/j.stem.2014.12.006. Epub 2015 Jan 22.

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