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Items: 1 to 20 of 176


Distance running alters peripheral microRNAs implicated in metabolism, fluid balance, and myosin regulation in a sex-specific manner.

Hicks SD, Jacob P, Middleton FA, Perez O, Gagnon Z.

Physiol Genomics. 2018 Jun 8. doi: 10.1152/physiolgenomics.00035.2018. [Epub ahead of print]


SHIP1 Deficiency in Inflammatory Bowel Disease Is Associated With Severe Crohn's Disease and Peripheral T Cell Reduction.

Fernandes S, Srivastava N, Sudan R, Middleton FA, Shergill AK, Ryan JC, Kerr WG.

Front Immunol. 2018 May 22;9:1100. doi: 10.3389/fimmu.2018.01100. eCollection 2018.


Crizotinib induces apoptosis and gene expression changes in ALK+ anaplastic large cell lymphoma cell lines; brentuximab synergizes and doxorubicin antagonizes.

Hudson S, Wang D, Middleton F, Nevaldine BH, Naous R, Hutchison RE.

Pediatr Blood Cancer. 2018 Apr 26:e27094. doi: 10.1002/pbc.27094. [Epub ahead of print]


Reviewer selection biases editorial decisions on manuscripts.

Hausmann L, Schweitzer B, Middleton FA, Schulz JB.

J Neurochem. 2018 Jan 27. doi: 10.1111/jnc.14314. [Epub ahead of print]


Reduced Slc1a1 expression is associated with neuroinflammation and impaired sensorimotor gating and cognitive performance in mice: Implications for schizophrenia.

Afshari P, Yao WD, Middleton FA.

PLoS One. 2017 Sep 8;12(9):e0183854. doi: 10.1371/journal.pone.0183854. eCollection 2017.


Contrast sensitivity to spatial gratings in moderate and dim light conditions in patients with diabetes in the absence of diabetic retinopathy.

Safi S, Rahimi A, Raeesi A, Safi H, Aghazadeh Amiri M, Malek M, Yaseri M, Haeri M, Middleton FA, Solessio E, Ahmadieh H.

BMJ Open Diabetes Res Care. 2017 Aug 8;5(1):e000408. doi: 10.1136/bmjdrc-2017-000408. eCollection 2017.


Analysis of SHIP1 expression and activity in Crohn's disease patients.

Somasundaram R, Fernandes S, Deuring JJ, de Haar C, Kuipers EJ, Vogelaar L, Middleton FA, van der Woude CJ, Peppelenbosch MP, Kerr WG, Fuhler GM.

PLoS One. 2017 Aug 2;12(8):e0182308. doi: 10.1371/journal.pone.0182308. eCollection 2017.


Heterogeneity of p53 dependent genomic responses following ethanol exposure in a developmental mouse model of fetal alcohol spectrum disorder.

Camargo Moreno M, Mooney SM, Middleton FA.

PLoS One. 2017 Jul 19;12(7):e0180873. doi: 10.1371/journal.pone.0180873. eCollection 2017.


The de novo autism spectrum disorder RELN R2290C mutation reduces Reelin secretion and increases protein disulfide isomerase expression.

Lammert DB, Middleton FA, Pan J, Olson EC, Howell BW.

J Neurochem. 2017 Jul;142(1):89-102. doi: 10.1111/jnc.14045. Epub 2017 May 18.


Analysis of Shared Haplotypes amongst Palauans Maps Loci for Psychotic Disorders to 4q28 and 5q23-q31.

Bodea CA, Middleton FA, Melhem NM, Klei L, Song Y, Tiobech J, Marumoto P, Yano V, Faraone SV, Roeder K, Myles-Worsley M, Devlin B, Byerley W.

Mol Neuropsychiatry. 2017 Feb;2(4):173-184. doi: 10.1159/000450726. Epub 2016 Oct 12.


Associations between neurodevelopmental genes, neuroanatomy, and ultra high risk symptoms of psychosis in 22q11.2 deletion syndrome.

Thompson CA, Karelis J, Middleton FA, Gentile K, Coman IL, Radoeva PD, Mehta R, Fremont WP, Antshel KM, Faraone SV, Kates WR.

Am J Med Genet B Neuropsychiatr Genet. 2017 Apr;174(3):295-314. doi: 10.1002/ajmg.b.32515. Epub 2017 Jan 31.


Cortical-amygdala volumetric ratios predict onset of symptoms of psychosis in 22q11.2 deletion syndrome.

Berhanu D, Mattiaccio LM, Antshel KM, Fremont W, Middleton FA, Kates WR.

Psychiatry Res Neuroimaging. 2017 Jan 30;259:10-15. doi: 10.1016/j.pscychresns.2016.11.006. Epub 2016 Nov 25.


A Comparative Review of microRNA Expression Patterns in Autism Spectrum Disorder.

Hicks SD, Middleton FA.

Front Psychiatry. 2016 Nov 4;7:176. eCollection 2016.


Thrombospondin-1 differentially regulates microRNAs in vascular smooth muscle cells.

Maier KG, Ruhle B, Stein JJ, Gentile KL, Middleton FA, Gahtan V.

Mol Cell Biochem. 2016 Jan;412(1-2):111-7. doi: 10.1007/s11010-015-2614-9. Epub 2016 Jan 4.


Common cancer-associated imbalances in the DNA damage response confer sensitivity to single agent ATR inhibition.

Middleton FK, Patterson MJ, Elstob CJ, Fordham S, Herriott A, Wade MA, McCormick A, Edmondson R, May FE, Allan JM, Pollard JR, Curtin NJ.

Oncotarget. 2015 Oct 20;6(32):32396-409. doi: 10.18632/oncotarget.6136.


Chk1 phosphorylated at serine345 is a predictor of early local recurrence and radio-resistance in breast cancer.

Alsubhi N, Middleton F, Abdel-Fatah TM, Stephens P, Doherty R, Arora A, Moseley PM, Chan SY, Aleskandarany MA, Green AR, Rakha EA, Ellis IO, Martin SG, Curtin NJ, Madhusudan S.

Mol Oncol. 2016 Feb;10(2):213-23. doi: 10.1016/j.molonc.2015.09.009. Epub 2015 Oct 3.


Characterization of a Novel Mutation in SLC1A1 Associated with Schizophrenia.

Afshari P, Myles-Worsley M, Cohen OS, Tiobech J, Faraone SV, Byerley W, Middleton FA.

Mol Neuropsychiatry. 2015 Oct;1(3):125-44. doi: 10.1159/000433599. Epub 2015 Jul 8.


A splicing-regulatory polymorphism in DRD2 disrupts ZRANB2 binding, impairs cognitive functioning and increases risk for schizophrenia in six Han Chinese samples.

Cohen OS, Weickert TW, Hess JL, Paish LM, McCoy SY, Rothmond DA, Galletly C, Liu D, Weinberg DD, Huang XF, Xu Q, Shen Y, Zhang D, Yue W, Yan J, Wang L, Lu T, He L, Shi Y, Xu M, Che R, Tang W, Chen CH, Chang WH, Hwu HG, Liu CM, Liu YL, Wen CC, Fann CS, Chang CC, Kanazawa T, Middleton FA, Duncan TM, Faraone SV, Weickert CS, Tsuang MT, Glatt SJ.

Mol Psychiatry. 2016 Jul;21(7):975-82. doi: 10.1038/mp.2015.137. Epub 2015 Sep 8.


Alterations in serum microRNA in humans with alcohol use disorders impact cell proliferation and cell death pathways and predict structural and functional changes in brain.

Ignacio C, Hicks SD, Burke P, Lewis L, Szombathyne-Meszaros Z, Middleton FA.

BMC Neurosci. 2015 Sep 5;16:55. doi: 10.1186/s12868-015-0195-x.

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