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STYK1 promotes autophagy through enhancing the assembly of autophagy-specific class III phosphatidylinositol 3-kinase complex I.

Zhou C, Qian X, Hu M, Zhang R, Liu N, Huang Y, Yang J, Zhang J, Bai H, Yang Y, Wang Y, Ali D, Michalak M, Chen XZ, Tang J.

Autophagy. 2019 Nov 7:1-21. doi: 10.1080/15548627.2019.1687212. [Epub ahead of print]


Epidemiologic and clinical features of chronic hepatitis B virus infection in 8 Canadian provinces: a descriptive study by the Canadian HBV Network.

Coffin CS, Ramji A, Cooper CL, Miles D, Doucette KE, Wong P, Tam E, Wong DK, Wong A, Ukabam S, Bailey RJ, Tsoi K, Conway B, Barrett L, Michalak TI, Congly SE, Minuk G, Kaita K, Kelly E, Ko HH, Janssen HLA, Uhanova J, Lethebe BC, Haylock-Jacobs S, Ma MM, Osiowy C, Fung SK; Canadian HBV Network.

CMAJ Open. 2019 Oct 22;7(4):E610-E617. doi: 10.9778/cmajo.20190103. Print 2019 Oct-Dec.


Avoiding raising the ire of IRE1α.

Agellon LB, Michalak M.

Cell Calcium. 2019 Nov;83:102056. doi: 10.1016/j.ceca.2019.102056. Epub 2019 Aug 8.


Organellar Calcium Handling in the Cellular Reticular Network.

Wang WA, Agellon LB, Michalak M.

Cold Spring Harb Perspect Biol. 2019 Jul 29. pii: a038265. doi: 10.1101/cshperspect.a038265. [Epub ahead of print]


Endoplasmic reticulum and the microRNA environment in the cardiovascular system 1.

Groenendyk J, Fan X, Peng Z, Kurgan L, Michalak M.

Can J Physiol Pharmacol. 2019 Jun;97(6):515-527. doi: 10.1139/cjpp-2018-0720. Epub 2019 May 7. Review.


Two pools of IRE1α in cardiac and skeletal muscle cells.

Wang Q, Groenendyk J, Paskevicius T, Qin W, Kor KC, Liu Y, Hiess F, Knollmann BC, Chen SRW, Tang J, Chen XZ, Agellon LB, Michalak M.

FASEB J. 2019 Aug;33(8):8892-8904. doi: 10.1096/fj.201802626R. Epub 2019 May 3.


Tauroursodeoxycholic acid attenuates cyclosporine-induced renal fibrogenesis in the mouse model.

Groenendyk J, Robinson A, Wang Q, Hu M, Tang J, Chen XZ, Mengel M, Alexander RT, Agellon LB, Michalak M.

Biochim Biophys Acta Gen Subj. 2019 Jul;1863(7):1210-1216. doi: 10.1016/j.bbagen.2019.04.016. Epub 2019 Apr 24.


Stress Coping Strategies in the Heart: An Integrated View.

Michalak M, Agellon LB.

Front Cardiovasc Med. 2018 Nov 21;5:168. doi: 10.3389/fcvm.2018.00168. eCollection 2018. Review.


Endoplasmic reticulum calcium dictates the distribution of intracellular unesterified cholesterol.

Wang WA, Agellon LB, Michalak M.

Cell Calcium. 2018 Dec;76:116-121. doi: 10.1016/j.ceca.2018.11.002. Epub 2018 Nov 10. Review.


Cyclosporine A binding to COX-2 reveals a novel signaling pathway that activates the IRE1α unfolded protein response sensor.

Groenendyk J, Paskevicius T, Urra H, Viricel C, Wang K, Barakat K, Hetz C, Kurgan L, Agellon LB, Michalak M.

Sci Rep. 2018 Nov 12;8(1):16678. doi: 10.1038/s41598-018-34891-w.


Importance of Nutrients and Nutrient Metabolism on Human Health.

Chen Y, Michalak M, Agellon LB.

Yale J Biol Med. 2018 Jun 28;91(2):95-103. eCollection 2018 Jun. Review.


Distribution and protection of climatic refugia in North America.

Michalak JL, Lawler JJ, Roberts DR, Carroll C.

Conserv Biol. 2018 Dec;32(6):1414-1425. doi: 10.1111/cobi.13130. Epub 2018 Aug 13.


Exploring New Cardiovascular Pathways: Are Soluble Guanylate Cyclase Stimulators the Right Direction?

Michalak M, Armstrong PW.

Circ Heart Fail. 2018 Mar;11(3):e004813. doi: 10.1161/CIRCHEARTFAILURE.118.004813. No abstract available.


Calnexin is necessary for T cell transmigration into the central nervous system.

Jung J, Eggleton P, Robinson A, Wang J, Gutowski N, Holley J, Newcombe J, Dudek E, Paul AM, Zochodne D, Kraus A, Power C, Agellon LB, Michalak M.

JCI Insight. 2018 Mar 8;3(5). pii: 98410. doi: 10.1172/jci.insight.98410.


Interactome Screening Identifies the ER Luminal Chaperone Hsp47 as a Regulator of the Unfolded Protein Response Transducer IRE1α.

Sepulveda D, Rojas-Rivera D, Rodríguez DA, Groenendyk J, Köhler A, Lebeaupin C, Ito S, Urra H, Carreras-Sureda A, Hazari Y, Vasseur-Cognet M, Ali MMU, Chevet E, Campos G, Godoy P, Vaisar T, Bailly-Maitre B, Nagata K, Michalak M, Sierralta J, Hetz C.

Mol Cell. 2018 Jan 18;69(2):238-252.e7. doi: 10.1016/j.molcel.2017.12.028.


Endoplasmic reticulum in health and disease: the 12th International Calreticulin Workshop, Delphi, Greece.

Charonis AS, Michalak M, Groenendyk J, Agellon LB.

J Cell Mol Med. 2017 Dec;21(12):3141-3149. doi: 10.1111/jcmm.13413. Epub 2017 Nov 21.


Relief of endoplasmic reticulum stress enhances DNA damage repair and improves development of pre-implantation embryos.

Dicks N, Bohrer RC, Gutierrez K, Michalak M, Agellon LB, Bordignon V.

PLoS One. 2017 Nov 3;12(11):e0187717. doi: 10.1371/journal.pone.0187717. eCollection 2017.


Fatty acid binding protein (Fabp) 5 interacts with the calnexin cytoplasmic domain at the endoplasmic reticulum.

Jung J, Wang J, Groenendyk J, Lee D, Michalak M, Agellon LB.

Biochem Biophys Res Commun. 2017 Nov 4;493(1):202-206. doi: 10.1016/j.bbrc.2017.09.046. Epub 2017 Sep 11.


Loss of Calreticulin Uncovers a Critical Role for Calcium in Regulating Cellular Lipid Homeostasis.

Wang WA, Liu WX, Durnaoglu S, Lee SK, Lian J, Lehner R, Ahnn J, Agellon LB, Michalak M.

Sci Rep. 2017 Jul 19;7(1):5941. doi: 10.1038/s41598-017-05734-x.


Scale-dependent complementarity of climatic velocity and environmental diversity for identifying priority areas for conservation under climate change.

Carroll C, Roberts DR, Michalak JL, Lawler JJ, Nielsen SE, Stralberg D, Hamann A, Mcrae BH, Wang T.

Glob Chang Biol. 2017 Nov;23(11):4508-4520. doi: 10.1111/gcb.13679. Epub 2017 Mar 31.


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