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Items: 1 to 20 of 93

1.

The Role of Platelet-Derived ADP and ATP in Promoting Pancreatic Cancer Cell Survival and Gemcitabine Resistance.

Elaskalani O, Falasca M, Moran N, Berndt MC, Metharom P.

Cancers (Basel). 2017 Oct 24;9(10). pii: E142. doi: 10.3390/cancers9100142.

2.

Corrigendum: 14-3-3ζ regulates the mitochondrial respiratory reserve linked to platelet phosphatidylserine exposure and procoagulant function.

Schoenwaelder SM, Darbousset R, Cranmer SL, Ramshaw HS, Orive SL, Sturgeon S, Yuan Y, Yao Y, Krycer JR, Woodcock J, Maclean J, Pitson S, Zheng Z, Henstridge DC, van der Wal D, Gardiner EE, Berndt MC, Andrews RK, James DE, Lopez AF, Jackson SP.

Nat Commun. 2017 Aug 30;8:16125. doi: 10.1038/ncomms16125.

3.

Targeting Platelets for the Treatment of Cancer.

Elaskalani O, Berndt MC, Falasca M, Metharom P.

Cancers (Basel). 2017 Jul 22;9(7). pii: E94. doi: 10.3390/cancers9070094. Review.

4.

Platelet clearance via shear-induced unfolding of a membrane mechanoreceptor.

Deng W, Xu Y, Chen W, Paul DS, Syed AK, Dragovich MA, Liang X, Zakas P, Berndt MC, Di Paola J, Ware J, Lanza F, Doering CB, Bergmeier W, Zhang XF, Li R.

Nat Commun. 2016 Sep 27;7:12863. doi: 10.1038/ncomms12863.

5.

14-3-3ζ regulates the mitochondrial respiratory reserve linked to platelet phosphatidylserine exposure and procoagulant function.

Schoenwaelder SM, Darbousset R, Cranmer SL, Ramshaw HS, Orive SL, Sturgeon S, Yuan Y, Yao Y, Krycer JR, Woodcock J, Maclean J, Pitson S, Zheng Z, Henstridge DC, van der Wal D, Gardiner EE, Berndt MC, Andrews RK, James DE, Lopez AF, Jackson SP.

Nat Commun. 2016 Sep 27;7:12862. doi: 10.1038/ncomms12862. Erratum in: Nat Commun. 2017 Aug 30;8:16125.

6.

Liver-mediated shedding of platelet GPVI.

Berndt MC, Andrews RK.

Blood. 2016 Aug 11;128(6):751-2. doi: 10.1182/blood-2016-07-723973. No abstract available.

7.

Thrombin-induced reactive oxygen species generation in platelets: A novel role for protease-activated receptor 4 and GPIbα.

Carrim N, Arthur JF, Hamilton JR, Gardiner EE, Andrews RK, Moran N, Berndt MC, Metharom P.

Redox Biol. 2015 Dec;6:640-7. doi: 10.1016/j.redox.2015.10.009. Epub 2015 Oct 28.

8.

COMP: an endogenous thrombin inhibitor.

Metharom P, Berndt MC.

Blood. 2015 Aug 13;126(7):831-2. doi: 10.1182/blood-2015-06-650846.

9.

Current state and novel approaches of antiplatelet therapy.

Metharom P, Berndt MC, Baker RI, Andrews RK.

Arterioscler Thromb Vasc Biol. 2015 Jun;35(6):1327-38. doi: 10.1161/ATVBAHA.114.303413. Epub 2015 Apr 2. Review.

10.

Role of focal adhesion tyrosine kinases in GPVI-dependent platelet activation and reactive oxygen species formation.

Carrim N, Walsh TG, Consonni A, Torti M, Berndt MC, Metharom P.

PLoS One. 2014 Nov 21;9(11):e113679. doi: 10.1371/journal.pone.0113679. eCollection 2014.

11.

The functional role of platelets in the regulation of angiogenesis.

Walsh TG, Metharom P, Berndt MC.

Platelets. 2015;26(3):199-211. doi: 10.3109/09537104.2014.909022. Epub 2014 May 15. Review.

PMID:
24832135
12.

Bernard-Soulier syndrome: an update.

Andrews RK, Berndt MC.

Semin Thromb Hemost. 2013 Sep;39(6):656-62. doi: 10.1055/s-0033-1353390. Epub 2013 Aug 8. Review.

PMID:
23929303
13.

LIM kinase-1 selectively promotes glycoprotein Ib-IX-mediated TXA2 synthesis, platelet activation, and thrombosis.

Estevez B, Stojanovic-Terpo A, Delaney MK, O'Brien KA, Berndt MC, Ruan C, Du X.

Blood. 2013 May 30;121(22):4586-94. doi: 10.1182/blood-2012-12-470765. Epub 2013 Apr 25.

14.

Platelet hem-immunoreceptor tyrosine-based activation motif receptors: at least one required.

Berndt MC, Andrews RK.

Arterioscler Thromb Vasc Biol. 2013 May;33(5):884-5. doi: 10.1161/ATVBAHA.113.301400. No abstract available.

15.

Mice lacking the ITIM-containing receptor G6b-B exhibit macrothrombocytopenia and aberrant platelet function.

Mazharian A, Wang YJ, Mori J, Bem D, Finney B, Heising S, Gissen P, White JG, Berndt MC, Gardiner EE, Nieswandt B, Douglas MR, Campbell RD, Watson SP, Senis YA.

Sci Signal. 2012 Oct 30;5(248):ra78. doi: 10.1126/scisignal.2002936.

16.

The role of Rac1 in glycoprotein Ib-IX-mediated signal transduction and integrin activation.

Delaney MK, Liu J, Zheng Y, Berndt MC, Du X.

Arterioscler Thromb Vasc Biol. 2012 Nov;32(11):2761-8. doi: 10.1161/ATVBAHA.112.254920. Epub 2012 Sep 20.

17.

An acquired defect associated with abnormal signaling of the platelet collagen receptor glycoprotein VI.

Qiao J, Arthur JF, Collecutt M, Shen Y, Mu FT, Berndt MC, Davis AK, Andrews RK, Gardiner EE.

Acta Haematol. 2012;128(4):233-41. doi: 10.1159/000340048. Epub 2012 Aug 24.

PMID:
22922528
18.

Constitutive dimerization of glycoprotein VI (GPVI) in resting platelets is essential for binding to collagen and activation in flowing blood.

Jung SM, Moroi M, Soejima K, Nakagaki T, Miura Y, Berndt MC, Gardiner EE, Howes JM, Pugh N, Bihan D, Watson SP, Farndale RW.

J Biol Chem. 2012 Aug 24;287(35):30000-13. doi: 10.1074/jbc.M112.359125. Epub 2012 Jul 6.

19.

Cadherin 6 has a functional role in platelet aggregation and thrombus formation.

Dunne E, Spring CM, Reheman A, Jin W, Berndt MC, Newman DK, Newman PJ, Ni H, Kenny D.

Arterioscler Thromb Vasc Biol. 2012 Jul;32(7):1724-31. doi: 10.1161/ATVBAHA.112.250464. Epub 2012 Apr 26.

20.

Pathologic shear triggers shedding of vascular receptors: a novel mechanism for down-regulation of platelet glycoprotein VI in stenosed coronary vessels.

Al-Tamimi M, Tan CW, Qiao J, Pennings GJ, Javadzadegan A, Yong AS, Arthur JF, Davis AK, Jing J, Mu FT, Hamilton JR, Jackson SP, Ludwig A, Berndt MC, Ward CM, Kritharides L, Andrews RK, Gardiner EE.

Blood. 2012 May 3;119(18):4311-20. doi: 10.1182/blood-2011-10-386607. Epub 2012 Mar 19.

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