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Items: 1 to 20 of 121

1.

Loss of LMOD1 impairs smooth muscle cytocontractility and causes megacystis microcolon intestinal hypoperistalsis syndrome in humans and mice.

Halim D, Wilson MP, Oliver D, Brosens E, Verheij JB, Han Y, Nanda V, Lyu Q, Doukas M, Stoop H, Brouwer RW, van IJcken WF, Slivano OJ, Burns AJ, Christie CK, de Mesy Bentley KL, Brooks AS, Tibboel D, Xu S, Jin ZG, Djuwantono T, Yan W, Alves MM, Hofstra RM, Miano JM.

Proc Natl Acad Sci U S A. 2017 Mar 28;114(13):E2739-E2747. doi: 10.1073/pnas.1620507114. Epub 2017 Mar 14.

2.

Serum response factor regulates smooth muscle contractility via myotonic dystrophy protein kinases and L-type calcium channels.

Lee MY, Park C, Ha SE, Park PJ, Berent RM, Jorgensen BG, Corrigan RD, Grainger N, Blair PJ, Slivano OJ, Miano JM, Ward SM, Smith TK, Sanders KM, Ro S.

PLoS One. 2017 Feb 2;12(2):e0171262. doi: 10.1371/journal.pone.0171262. eCollection 2017.

3.

Novel Thrombotic Function of a Human SNP in STXBP5 Revealed by CRISPR/Cas9 Gene Editing in Mice.

Zhu QM, Ko KA, Ture S, Mastrangelo MA, Chen MH, Johnson AD, O'Donnell CJ, Morrell CN, Miano JM, Lowenstein CJ.

Arterioscler Thromb Vasc Biol. 2017 Feb;37(2):264-270. doi: 10.1161/ATVBAHA.116.308614. Epub 2016 Dec 29.

PMID:
28062498
4.

Maternal deprivation alters expression of neural maturation gene tbr1 in the amygdala paralaminar nucleus in infant female macaques.

de Campo DM, Cameron JL, Miano JM, Lewis DA, Mirnics K, Fudge JL.

Dev Psychobiol. 2017 Mar;59(2):235-249. doi: 10.1002/dev.21493. Epub 2016 Dec 4.

PMID:
27917473
5.

Testosterone Rescues the De-Differentiation of Smooth Muscle Cells Through Serum Response Factor/Myocardin.

Leimgruber C, Quintar AA, Peinetti N, Scalerandi MV, Nicola JP, Miano JM, Maldonado CA.

J Cell Physiol. 2016 Nov 9. doi: 10.1002/jcp.25679. [Epub ahead of print]

PMID:
27861881
6.

Challenges and Opportunities in Linking Long Noncoding RNAs to Cardiovascular, Lung, and Blood Diseases.

Freedman JE, Miano JM; National Heart, Lung, and Blood Institute Workshop Participants*..

Arterioscler Thromb Vasc Biol. 2017 Jan;37(1):21-25. doi: 10.1161/ATVBAHA.116.308513. Epub 2016 Nov 17.

PMID:
27856459
7.

Vascular smooth muscle cell contractile protein expression is increased through protein kinase G-dependent and -independent pathways by glucose-6-phosphate dehydrogenase inhibition and deficiency.

Chettimada S, Joshi SR, Dhagia V, Aiezza A 2nd, Lincoln TM, Gupte R, Miano JM, Gupte SA.

Am J Physiol Heart Circ Physiol. 2016 Oct 1;311(4):H904-H912. doi: 10.1152/ajpheart.00335.2016. Epub 2016 Aug 12.

PMID:
27521420
8.

MYOSLID Is a Novel Serum Response Factor-Dependent Long Noncoding RNA That Amplifies the Vascular Smooth Muscle Differentiation Program.

Zhao J, Zhang W, Lin M, Wu W, Jiang P, Tou E, Xue M, Richards A, Jourd'heuil D, Asif A, Zheng D, Singer HA, Miano JM, Long X.

Arterioscler Thromb Vasc Biol. 2016 Oct;36(10):2088-99. doi: 10.1161/ATVBAHA.116.307879. Epub 2016 Jul 21.

PMID:
27444199
9.

A CRISPR Path to Engineering New Genetic Mouse Models for Cardiovascular Research.

Miano JM, Zhu QM, Lowenstein CJ.

Arterioscler Thromb Vasc Biol. 2016 Jun;36(6):1058-75. doi: 10.1161/ATVBAHA.116.304790. Epub 2016 Apr 21.

PMID:
27102963
10.

Smooth Muscle Enriched Long Noncoding RNA (SMILR) Regulates Cell Proliferation.

Ballantyne MD, Pinel K, Dakin R, Vesey AT, Diver L, Mackenzie R, Garcia R, Welsh P, Sattar N, Hamilton G, Joshi N, Dweck MR, Miano JM, McBride MW, Newby DE, McDonald RA, Baker AH.

Circulation. 2016 May 24;133(21):2050-65. doi: 10.1161/CIRCULATIONAHA.115.021019. Epub 2016 Apr 6.

11.

A Role for the Long Noncoding RNA SENCR in Commitment and Function of Endothelial Cells.

Boulberdaa M, Scott E, Ballantyne M, Garcia R, Descamps B, Angelini GD, Brittan M, Hunter A, McBride M, McClure J, Miano JM, Emanueli C, Mills NL, Mountford JC, Baker AH.

Mol Ther. 2016 May;24(5):978-90. doi: 10.1038/mt.2016.41. Epub 2016 Feb 22.

12.

Loss of serum response factor induces microRNA-mediated apoptosis in intestinal smooth muscle cells.

Park C, Lee MY, Slivano OJ, Park PJ, Ha S, Berent RM, Fuchs R, Collins NC, Yu TJ, Syn H, Park JK, Horiguchi K, Miano JM, Sanders KM, Ro S.

Cell Death Dis. 2015 Dec 3;6:e2011. doi: 10.1038/cddis.2015.353.

13.

Serum Response Factor Is Essential for Prenatal Gastrointestinal Smooth Muscle Development and Maintenance of Differentiated Phenotype.

Park C, Lee MY, Park PJ, Ha SE, Berent RM, Fuchs R, Miano JM, Becker LS, Sanders KM, Ro S.

J Neurogastroenterol Motil. 2015 Oct 1;21(4):589-602. doi: 10.5056/jnm15063.

14.

Myocardin Family Members Drive Formation of Caveolae.

Krawczyk KK, Yao Mattisson I, Ekman M, Oskolkov N, Grantinge R, Kotowska D, Olde B, Hansson O, Albinsson S, Miano JM, Rippe C, Swärd K.

PLoS One. 2015 Aug 5;10(8):e0133931. doi: 10.1371/journal.pone.0133931. eCollection 2015.

15.

Smooth Muscle Cell Genome Browser: Enabling the Identification of Novel Serum Response Factor Target Genes.

Lee MY, Park C, Berent RM, Park PJ, Fuchs R, Syn H, Chin A, Townsend J, Benson CC, Redelman D, Shen TW, Park JK, Miano JM, Sanders KM, Ro S.

PLoS One. 2015 Aug 4;10(8):e0133751. doi: 10.1371/journal.pone.0133751. eCollection 2015.

16.

The short and long of noncoding sequences in the control of vascular cell phenotypes.

Miano JM, Long X.

Cell Mol Life Sci. 2015 Sep;72(18):3457-88. doi: 10.1007/s00018-015-1936-9. Epub 2015 May 29. Review.

17.

Myocardin in biology and disease.

Miano JM.

J Biomed Res. 2015 Jan;29(1):3-19. doi: 10.7555/JBR.29.20140151. Epub 2014 Dec 25. Review.

18.

Myocardin regulates vascular smooth muscle cell inflammatory activation and disease.

Ackers-Johnson M, Talasila A, Sage AP, Long X, Bot I, Morrell NW, Bennett MR, Miano JM, Sinha S.

Arterioscler Thromb Vasc Biol. 2015 Apr;35(4):817-28. doi: 10.1161/ATVBAHA.114.305218. Epub 2015 Jan 22.

19.

Cholesterol loading reprograms the microRNA-143/145-myocardin axis to convert aortic smooth muscle cells to a dysfunctional macrophage-like phenotype.

Vengrenyuk Y, Nishi H, Long X, Ouimet M, Savji N, Martinez FO, Cassella CP, Moore KJ, Ramsey SA, Miano JM, Fisher EA.

Arterioscler Thromb Vasc Biol. 2015 Mar;35(3):535-46. doi: 10.1161/ATVBAHA.114.304029. Epub 2015 Jan 8.

20.

CRISPR-Cas9 genome editing of a single regulatory element nearly abolishes target gene expression in mice--brief report.

Han Y, Slivano OJ, Christie CK, Cheng AW, Miano JM.

Arterioscler Thromb Vasc Biol. 2015 Feb;35(2):312-5. doi: 10.1161/ATVBAHA.114.305017. Epub 2014 Dec 23.

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