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Items: 1 to 20 of 196

1.

Charting cellular identity during human in vitro β-cell differentiation.

Veres A, Faust AL, Bushnell HL, Engquist EN, Kenty JH, Harb G, Poh YC, Sintov E, Gürtler M, Pagliuca FW, Peterson QP, Melton DA.

Nature. 2019 May;569(7756):368-373. doi: 10.1038/s41586-019-1168-5. Epub 2019 May 8.

PMID:
31068696
2.

Generation of hypoimmunogenic human pluripotent stem cells.

Han X, Wang M, Duan S, Franco PJ, Kenty JH, Hedrick P, Xia Y, Allen A, Ferreira LMR, Strominger JL, Melton DA, Meissner TB, Cowan CA.

Proc Natl Acad Sci U S A. 2019 Apr 30. pii: 201902566. doi: 10.1073/pnas.1902566116. [Epub ahead of print]

PMID:
31040209
3.

YAP inhibition enhances the differentiation of functional stem cell-derived insulin-producing β cells.

Rosado-Olivieri EA, Anderson K, Kenty JH, Melton DA.

Nat Commun. 2019 Apr 1;10(1):1464. doi: 10.1038/s41467-019-09404-6.

4.

Regenerating the field of cardiovascular cell therapy.

Chien KR, Frisén J, Fritsche-Danielson R, Melton DA, Murry CE, Weissman IL.

Nat Biotechnol. 2019 Mar;37(3):232-237. doi: 10.1038/s41587-019-0042-1. Epub 2019 Feb 18. Review.

PMID:
30778231
5.

Alginate-microencapsulation of human stem cell-derived β cells with CXCL12 prolongs their survival and function in immunocompetent mice without systemic immunosuppression.

Alagpulinsa DA, Cao JJL, Driscoll RK, Sîrbulescu RF, Penson MFE, Sremac M, Engquist EN, Brauns TA, Markmann JF, Melton DA, Poznansky MC.

Am J Transplant. 2019 Feb 12. doi: 10.1111/ajt.15308. [Epub ahead of print]

PMID:
30748094
6.

Blastemal progenitors modulate immune signaling during early limb regeneration.

Tsai SL, Baselga-Garriga C, Melton DA.

Development. 2019 Jan 2;146(1). pii: dev169128. doi: 10.1242/dev.169128.

PMID:
30602532
7.

Apolipoprotein E is a pancreatic extracellular factor that maintains mature β-cell gene expression.

Mahmoud AI, Galdos FX, Dinan KA, Jedrychowski MP, Davis JC, Vujic A, Rachmin I, Shigley C, Pancoast JR, Lee S, Hollister-Lock J, MacGillivray CM, Gygi SP, Melton DA, Weir GC, Lee RT.

PLoS One. 2018 Oct 10;13(10):e0204595. doi: 10.1371/journal.pone.0204595. eCollection 2018.

8.

Author Correction: Pancreas regeneration.

Zhou Q, Melton DA.

Nature. 2018 Aug;560(7720):E34. doi: 10.1038/s41586-018-0294-9.

PMID:
29925956
9.

Pancreas regeneration.

Zhou Q, Melton DA.

Nature. 2018 May;557(7705):351-358. doi: 10.1038/s41586-018-0088-0. Epub 2018 May 16. Review. Erratum in: Nature. 2018 Aug;560(7720):E34.

10.

Establishment of human pluripotent stem cell-derived pancreatic β-like cells in the mouse pancreas.

Ma H, Wert KJ, Shvartsman D, Melton DA, Jaenisch R.

Proc Natl Acad Sci U S A. 2018 Apr 10;115(15):3924-3929. doi: 10.1073/pnas.1702059115. Epub 2018 Mar 29.

11.

Retraction Notice to: Betatrophin: A Hormone that Controls Pancreatic β Cell Proliferation.

Yi P, Park JS, Melton DA.

Cell. 2017 Jan 12;168(1-2):326. doi: 10.1016/j.cell.2016.12.017. Epub 2016 Dec 28. No abstract available.

12.

A Single-Cell Transcriptomic Map of the Human and Mouse Pancreas Reveals Inter- and Intra-cell Population Structure.

Baron M, Veres A, Wolock SL, Faust AL, Gaujoux R, Vetere A, Ryu JH, Wagner BK, Shen-Orr SS, Klein AM, Melton DA, Yanai I.

Cell Syst. 2016 Oct 26;3(4):346-360.e4. doi: 10.1016/j.cels.2016.08.011. Epub 2016 Sep 22.

13.

Corrigendum: Generation of stem cell-derived β-cells from patients with type 1 diabetes.

Millman JR, Xie C, Van Dervort A, Gürtler M, Pagliuca FW, Melton DA.

Nat Commun. 2016 Aug 4;7:12379. doi: 10.1038/ncomms12379. No abstract available.

14.

Resolving Discrepant Findings on ANGPTL8 in β-Cell Proliferation: A Collaborative Approach to Resolving the Betatrophin Controversy.

Cox AR, Barrandon O, Cai EP, Rios JS, Chavez J, Bonnyman CW, Lam CJ, Yi P, Melton DA, Kushner JA.

PLoS One. 2016 Jul 13;11(7):e0159276. doi: 10.1371/journal.pone.0159276. eCollection 2016.

15.

Generation of stem cell-derived β-cells from patients with type 1 diabetes.

Millman JR, Xie C, Van Dervort A, Gürtler M, Pagliuca FW, Melton DA.

Nat Commun. 2016 May 10;7:11463. doi: 10.1038/ncomms11463. Erratum in: Nat Commun. 2016 Aug 04;7:12379.

16.

Corrigendum: Long-term glycemic control using polymer-encapsulated human stem cell-derived beta cells in immune-competent mice.

Vegas AJ, Veiseh O, Gürtler M, Millman JR, Pagliuca FW, Bader AR, Doloff JC, Li J, Chen M, Olejnik K, Tam HH, Jhunjhunwala S, Langan E, Aresta-Dasilva S, Gandham S, McGarrigle JJ, Bochenek MA, Hollister-Lock J, Oberholzer J, Greiner DL, Weir GC, Melton DA, Langer R, Anderson DG.

Nat Med. 2016 Apr;22(4):446. doi: 10.1038/nm0416-446e. No abstract available.

PMID:
27050590
17.

Applied Developmental Biology: Making Human Pancreatic Beta Cells for Diabetics.

Melton DA.

Curr Top Dev Biol. 2016;117:65-73. doi: 10.1016/bs.ctdb.2015.11.013. Epub 2016 Jan 20. Review.

PMID:
26969972
18.

Reprogrammed Stomach Tissue as a Renewable Source of Functional β Cells for Blood Glucose Regulation.

Ariyachet C, Tovaglieri A, Xiang G, Lu J, Shah MS, Richmond CA, Verbeke C, Melton DA, Stanger BZ, Mooney D, Shivdasani RA, Mahony S, Xia Q, Breault DT, Zhou Q.

Cell Stem Cell. 2016 Mar 3;18(3):410-21. doi: 10.1016/j.stem.2016.01.003. Epub 2016 Feb 18.

19.

Long-term glycemic control using polymer-encapsulated human stem cell-derived beta cells in immune-competent mice.

Vegas AJ, Veiseh O, Gürtler M, Millman JR, Pagliuca FW, Bader AR, Doloff JC, Li J, Chen M, Olejnik K, Tam HH, Jhunjhunwala S, Langan E, Aresta-Dasilva S, Gandham S, McGarrigle JJ, Bochenek MA, Hollister-Lock J, Oberholzer J, Greiner DL, Weir GC, Melton DA, Langer R, Anderson DG.

Nat Med. 2016 Mar;22(3):306-11. doi: 10.1038/nm.4030. Epub 2016 Jan 25. Erratum in: Nat Med. 2016 Apr;22(4):446.

20.

Angptl4 links α-cell proliferation following glucagon receptor inhibition with adipose tissue triglyceride metabolism.

Ben-Zvi D, Barrandon O, Hadley S, Blum B, Peterson QP, Melton DA.

Proc Natl Acad Sci U S A. 2015 Dec 15;112(50):15498-503. doi: 10.1073/pnas.1513872112. Epub 2015 Nov 30.

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