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Items: 1 to 20 of 132

1.

Classification and adaptive behavior prediction of children with autism spectrum disorder based upon multivariate data analysis of markers of oxidative stress and DNA methylation.

Howsmon DP, Kruger U, Melnyk S, James SJ, Hahn J.

PLoS Comput Biol. 2017 Mar 16;13(3):e1005385. doi: 10.1371/journal.pcbi.1005385. eCollection 2017 Mar.

2.

Overexpression of LINE-1 Retrotransposons in Autism Brain.

Shpyleva S, Melnyk S, Pavliv O, Pogribny I, Jill James S.

Mol Neurobiol. 2017 Feb 20. doi: 10.1007/s12035-017-0421-x. [Epub ahead of print]

PMID:
28220356
3.

Thyroid dysfunction in children with autism spectrum disorder is associated with folate receptor α autoimmune disorder.

Frye RE, Wynne R, Rose S, Slattery J, Delhey L, Tippett M, Kahler SG, Bennuri SC, Melnyk S, Sequeira JM, Quadros EV.

J Neuroendocrinol. 2017 Mar;29(3). doi: 10.1111/jne.12461.

PMID:
28199771
4.

Mathematical modeling of the methionine cycle and transsulfuration pathway in individuals with autism spectrum disorder.

Vargason T, Howsmon DP, Melnyk S, James SJ, Hahn J.

J Theor Biol. 2017 Mar 7;416:28-37. doi: 10.1016/j.jtbi.2016.12.021. Epub 2016 Dec 29.

PMID:
28040439
5.

Editor's Highlight: Organ-Specific Epigenetic Changes Induced by the Nongenotoxic Liver Carcinogen Methapyrilene in Fischer 344 Rats.

Shpyleva S, Dreval K, de Conti A, Kindrat I, Melnyk S, Yan J, Chen T, Beland FA, Pogribny IP.

Toxicol Sci. 2017 Mar 1;156(1):190-198. doi: 10.1093/toxsci/kfw242.

PMID:
28013212
6.

Mitochondrial and redox abnormalities in autism lymphoblastoid cells: a sibling control study.

Rose S, Bennuri SC, Wynne R, Melnyk S, James SJ, Frye RE.

FASEB J. 2017 Mar;31(3):904-909. doi: 10.1096/fj.201601004R. Epub 2016 Nov 18.

PMID:
27864377
7.

Modulation of mitochondrial function by the microbiome metabolite propionic acid in autism and control cell lines.

Frye RE, Rose S, Chacko J, Wynne R, Bennuri SC, Slattery JC, Tippett M, Delhey L, Melnyk S, Kahler SG, MacFabe DF.

Transl Psychiatry. 2016 Oct 25;6(10):e927. doi: 10.1038/tp.2016.189.

8.

Loss of C/EBPδ enhances IR-induced cell death by promoting oxidative stress and mitochondrial dysfunction.

Banerjee S, Aykin-Burns N, Krager KJ, Shah SK, Melnyk SB, Hauer-Jensen M, Pawar SA.

Free Radic Biol Med. 2016 Oct;99:296-307. doi: 10.1016/j.freeradbiomed.2016.08.022. Epub 2016 Aug 20.

9.

Folinic acid improves verbal communication in children with autism and language impairment: a randomized double-blind placebo-controlled trial.

Frye RE, Slattery J, Delhey L, Furgerson B, Strickland T, Tippett M, Sailey A, Wynne R, Rose S, Melnyk S, Jill James S, Sequeira JM, Quadros EV.

Mol Psychiatry. 2016 Oct 18. doi: 10.1038/mp.2016.168. [Epub ahead of print]

PMID:
27752075
10.

Open-label randomized trial of titrated disease management for patients with hypertension: Study design and baseline sample characteristics.

Jackson GL, Weinberger M, Kirshner MA, Stechuchak KM, Melnyk SD, Bosworth HB, Coffman CJ, Neelon B, Van Houtven C, Gentry PW, Morris IJ, Rose CM, Taylor JP, May CL, Han B, Wainwright C, Alkon A, Powell L, Edelman D.

Contemp Clin Trials. 2016 Sep;50:5-15. doi: 10.1016/j.cct.2016.07.009. Epub 2016 Jul 12.

PMID:
27417982
11.

Metabolic history impacts mammary tumor epithelial hierarchy and early drug response in mice.

Montales MT, Melnyk SB, Liu SJ, Simmen FA, Liu YL, Simmen RC.

Endocr Relat Cancer. 2016 Sep;23(9):677-90. doi: 10.1530/ERC-16-0136. Epub 2016 Jul 8.

PMID:
27402613
12.

High-Fat Diet Promotion of Endometriosis in an Immunocompetent Mouse Model is Associated With Altered Peripheral and Ectopic Lesion Redox and Inflammatory Status.

Heard ME, Melnyk SB, Simmen FA, Yang Y, Pabona JM, Simmen RC.

Endocrinology. 2016 Jul;157(7):2870-82. doi: 10.1210/en.2016-1092. Epub 2016 May 13.

PMID:
27175969
13.

Effects of local irradiation combined with sunitinib on early remodeling, mitochondria, and oxidative stress in the rat heart.

Sridharan V, Thomas CJ, Cao M, Melnyk SB, Pavliv O, Joseph J, Singh SP, Sharma S, Moros EG, Boerma M.

Radiother Oncol. 2016 May;119(2):259-64. doi: 10.1016/j.radonc.2016.03.027. Epub 2016 Apr 9.

PMID:
27072940
14.

Sex-specific effects of cytotoxic chemotherapy agents cyclophosphamide and mitomycin C on gene expression, oxidative DNA damage, and epigenetic alterations in the prefrontal cortex and hippocampus - an aging connection.

Kovalchuk A, Rodriguez-Juarez R, Ilnytskyy Y, Byeon B, Shpyleva S, Melnyk S, Pogribny I, Kolb B, Kovalchuk O.

Aging (Albany NY). 2016 Apr;8(4):697-711. doi: 10.18632/aging.100920.

15.

Blocking and Binding Folate Receptor Alpha Autoantibodies Identify Novel Autism Spectrum Disorder Subgroups.

Frye RE, Delhey L, Slattery J, Tippett M, Wynne R, Rose S, Kahler SG, Bennuri SC, Melnyk S, Sequeira JM, Quadros E.

Front Neurosci. 2016 Mar 9;10:80. doi: 10.3389/fnins.2016.00080. eCollection 2016.

16.

Radiation-induced changes in DNA methylation of repetitive elements in the mouse heart.

Koturbash I, Miousse IR, Sridharan V, Nzabarushimana E, Skinner CM, Melnyk SB, Pavliv O, Hauer-Jensen M, Nelson GA, Boerma M.

Mutat Res. 2016 May;787:43-53. doi: 10.1016/j.mrfmmm.2016.02.009. Epub 2016 Mar 2.

PMID:
26963372
17.

Inflammatory and oxidative stress-related effects associated with neurotoxicity are maintained after exclusively prenatal trichloroethylene exposure.

Blossom SJ, Melnyk SB, Li M, Wessinger WD, Cooney CA.

Neurotoxicology. 2017 Mar;59:164-174. doi: 10.1016/j.neuro.2016.01.002. Epub 2016 Jan 23.

PMID:
26812193
18.

In vivo epigenetic effects induced by engineered nanomaterials: A case study of copper oxide and laser printer-emitted engineered nanoparticles.

Lu X, Miousse IR, Pirela SV, Moore JK, Melnyk S, Koturbash I, Demokritou P.

Nanotoxicology. 2016;10(5):629-39. doi: 10.3109/17435390.2015.1108473. Epub 2015 Nov 11.

PMID:
26559097
19.

The neuronal nitric oxide synthase inhibitor NANT blocks acetaminophen toxicity and protein nitration in freshly isolated hepatocytes.

Banerjee S, Melnyk SB, Krager KJ, Aykin-Burns N, Letzig LG, James LP, Hinson JA.

Free Radic Biol Med. 2015 Dec;89:750-7. doi: 10.1016/j.freeradbiomed.2015.09.022. Epub 2015 Oct 9.

20.

The neurobehavioral and molecular phenotype of Angelman Syndrome.

Wink LK, Fitzpatrick S, Shaffer R, Melnyk S, Begtrup AH, Fox E, Schaefer TL, Mathieu-Frasier L, Ray B, Lahiri D, Horn PA, Erickson CA.

Am J Med Genet A. 2015 Nov;167A(11):2623-8. doi: 10.1002/ajmg.a.37254. Epub 2015 Jul 29.

PMID:
26219744

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