Format
Sort by
Items per page

Send to

Choose Destination

Search results

Items: 1 to 20 of 37

1.

Erratum: Indexing the Pseudomonas specialized metabolome enabled the discovery of poaeamide B and the bananamides.

Nguyen DD, Melnik AV, Koyama N, Lu X, Schorn M, Fang J, Aguinaldo K, Lincecum TL Jr, Ghequire MG, Carrion VJ, Cheng TL, Duggan BM, Malone JG, Mauchline TH, Sanchez LM, Kilpatrick AM, Raaijmakers JM, De Mot R, Moore BS, Medema MH, Dorrestein PC.

Nat Microbiol. 2017 Jan 23;2:17010. doi: 10.1038/nmicrobiol.2017.10. No abstract available.

PMID:
28112718
2.

The antiSMASH database, a comprehensive database of microbial secondary metabolite biosynthetic gene clusters.

Blin K, Medema MH, Kottmann R, Lee SY, Weber T.

Nucleic Acids Res. 2017 Jan 4;45(D1):D555-D559. doi: 10.1093/nar/gkw960.

3.

Indexing the Pseudomonas specialized metabolome enabled the discovery of poaeamide B and the bananamides.

Nguyen DD, Melnik AV, Koyama N, Lu X, Schorn M, Fang J, Aguinaldo K, Lincecum TL Jr, Ghequire MG, Carrion VJ, Cheng TL, Duggan BM, Malone JG, Mauchline TH, Sanchez LM, Kilpatrick AM, Raaijmakers JM, Mot R, Moore BS, Medema MH, Dorrestein PC.

Nat Microbiol. 2016 Oct 31;2:16197. doi: 10.1038/nmicrobiol.2016.197.

PMID:
27798598
4.

Editorial: Synthetic biology and bioinformatics.

Medema MH, Zhao H.

Nat Prod Rep. 2016 Aug 27;33(8):913-4. doi: 10.1039/c6np90031c. No abstract available.

PMID:
27438694
5.

Computational genomic identification and functional reconstitution of plant natural product biosynthetic pathways.

Medema MH, Osbourn A.

Nat Prod Rep. 2016 Aug 27;33(8):951-62. doi: 10.1039/c6np00035e.

6.

Standardization for natural product synthetic biology.

Zhao H, Medema MH.

Nat Prod Rep. 2016 Aug 27;33(8):920-4. doi: 10.1039/c6np00030d.

PMID:
27313083
7.

Comprehensive curation and analysis of fungal biosynthetic gene clusters of published natural products.

Li YF, Tsai KJ, Harvey CJ, Li JJ, Ary BE, Berlew EE, Boehman BL, Findley DM, Friant AG, Gardner CA, Gould MP, Ha JH, Lilley BK, McKinstry EL, Nawal S, Parry RC, Rothchild KW, Silbert SD, Tentilucci MD, Thurston AM, Wai RB, Yoon Y, Aiyar RS, Medema MH, Hillenmeyer ME, Charkoudian LK.

Fungal Genet Biol. 2016 Apr;89:18-28. doi: 10.1016/j.fgb.2016.01.012.

PMID:
26808821
8.

Computational strategies for genome-based natural product discovery and engineering in fungi.

van der Lee TA, Medema MH.

Fungal Genet Biol. 2016 Apr;89:29-36. doi: 10.1016/j.fgb.2016.01.006. Review.

9.

Leucanicidin and Endophenasides Result from Methyl-Rhamnosylation by the Same Tailoring Enzymes in Kitasatospora sp. MBT66.

Wu C, Medema MH, Läkamp RM, Zhang L, Dorrestein PC, Choi YH, van Wezel GP.

ACS Chem Biol. 2016 Feb 19;11(2):478-90. doi: 10.1021/acschembio.5b00801.

PMID:
26675041
10.

Genomic mutational analysis of the impact of the classical strain improvement program on β-lactam producing Penicillium chrysogenum.

Salo OV, Ries M, Medema MH, Lankhorst PP, Vreeken RJ, Bovenberg RA, Driessen AJ.

BMC Genomics. 2015 Nov 14;16:937. doi: 10.1186/s12864-015-2154-4.

11.

Computational approaches to natural product discovery.

Medema MH, Fischbach MA.

Nat Chem Biol. 2015 Sep;11(9):639-48. doi: 10.1038/nchembio.1884.

12.

Minimum Information about a Biosynthetic Gene cluster.

Medema MH, Kottmann R, Yilmaz P, Cummings M, Biggins JB, Blin K, de Bruijn I, Chooi YH, Claesen J, Coates RC, Cruz-Morales P, Duddela S, Düsterhus S, Edwards DJ, Fewer DP, Garg N, Geiger C, Gomez-Escribano JP, Greule A, Hadjithomas M, Haines AS, Helfrich EJ, Hillwig ML, Ishida K, Jones AC, Jones CS, Jungmann K, Kegler C, Kim HU, Kötter P, Krug D, Masschelein J, Melnik AV, Mantovani SM, Monroe EA, Moore M, Moss N, Nützmann HW, Pan G, Pati A, Petras D, Reen FJ, Rosconi F, Rui Z, Tian Z, Tobias NJ, Tsunematsu Y, Wiemann P, Wyckoff E, Yan X, Yim G, Yu F, Xie Y, Aigle B, Apel AK, Balibar CJ, Balskus EP, Barona-Gómez F, Bechthold A, Bode HB, Borriss R, Brady SF, Brakhage AA, Caffrey P, Cheng YQ, Clardy J, Cox RJ, De Mot R, Donadio S, Donia MS, van der Donk WA, Dorrestein PC, Doyle S, Driessen AJ, Ehling-Schulz M, Entian KD, Fischbach MA, Gerwick L, Gerwick WH, Gross H, Gust B, Hertweck C, Höfte M, Jensen SE, Ju J, Katz L, Kaysser L, Klassen JL, Keller NP, Kormanec J, Kuipers OP, Kuzuyama T, Kyrpides NC, Kwon HJ, Lautru S, Lavigne R, Lee CY, Linquan B, Liu X, Liu W, Luzhetskyy A, Mahmud T, Mast Y, Méndez C, Metsä-Ketelä M, Micklefield J, Mitchell DA, Moore BS, Moreira LM, Müller R, Neilan BA, Nett M, Nielsen J, O'Gara F, Oikawa H, Osbourn A, Osburne MS, Ostash B, Payne SM, Pernodet JL, Petricek M, Piel J, Ploux O, Raaijmakers JM, Salas JA, Schmitt EK, Scott B, Seipke RF, Shen B, Sherman DH, Sivonen K, Smanski MJ, Sosio M, Stegmann E, Süssmuth RD, Tahlan K, Thomas CM, Tang Y, Truman AW, Viaud M, Walton JD, Walsh CT, Weber T, van Wezel GP, Wilkinson B, Willey JM, Wohlleben W, Wright GD, Ziemert N, Zhang C, Zotchev SB, Breitling R, Takano E, Glöckner FO.

Nat Chem Biol. 2015 Sep;11(9):625-31. doi: 10.1038/nchembio.1890. No abstract available.

PMID:
26284661
13.

antiSMASH 3.0-a comprehensive resource for the genome mining of biosynthetic gene clusters.

Weber T, Blin K, Duddela S, Krug D, Kim HU, Bruccoleri R, Lee SY, Fischbach MA, Müller R, Wohlleben W, Breitling R, Takano E, Medema MH.

Nucleic Acids Res. 2015 Jul 1;43(W1):W237-43. doi: 10.1093/nar/gkv437.

14.

Functional Exchangeability of Oxidase and Dehydrogenase Reactions in the Biosynthesis of Hydroxyphenylglycine, a Nonribosomal Peptide Building Block.

Diez V, Loznik M, Taylor S, Winn M, Rattray NJ, Podmore H, Micklefield J, Goodacre R, Medema MH, Müller U, Bovenberg R, Janssen DB, Takano E.

ACS Synth Biol. 2015 Jul 17;4(7):796-807. doi: 10.1021/sb500368w.

PMID:
25713978
15.

A systematic computational analysis of biosynthetic gene cluster evolution: lessons for engineering biosynthesis.

Medema MH, Cimermancic P, Sali A, Takano E, Fischbach MA.

PLoS Comput Biol. 2014 Dec 4;10(12):e1004016. doi: 10.1371/journal.pcbi.1004016. Erratum in: PLoS Comput Biol. 2016 Mar;12(3):e1004767.

16.

Pep2Path: automated mass spectrometry-guided genome mining of peptidic natural products.

Medema MH, Paalvast Y, Nguyen DD, Melnik A, Dorrestein PC, Takano E, Breitling R.

PLoS Comput Biol. 2014 Sep 4;10(9):e1003822. doi: 10.1371/journal.pcbi.1003822.

17.

Insights into secondary metabolism from a global analysis of prokaryotic biosynthetic gene clusters.

Cimermancic P, Medema MH, Claesen J, Kurita K, Wieland Brown LC, Mavrommatis K, Pati A, Godfrey PA, Koehrsen M, Clardy J, Birren BW, Takano E, Sali A, Linington RG, Fischbach MA.

Cell. 2014 Jul 17;158(2):412-21. doi: 10.1016/j.cell.2014.06.034.

18.

MS/MS networking guided analysis of molecule and gene cluster families.

Nguyen DD, Wu CH, Moree WJ, Lamsa A, Medema MH, Zhao X, Gavilan RG, Aparicio M, Atencio L, Jackson C, Ballesteros J, Sanchez J, Watrous JD, Phelan VV, van de Wiel C, Kersten RD, Mehnaz S, De Mot R, Shank EA, Charusanti P, Nagarajan H, Duggan BM, Moore BS, Bandeira N, Palsson BØ, Pogliano K, Gutiérrez M, Dorrestein PC.

Proc Natl Acad Sci U S A. 2013 Jul 9;110(28):E2611-20. doi: 10.1073/pnas.1303471110.

19.

antiSMASH 2.0--a versatile platform for genome mining of secondary metabolite producers.

Blin K, Medema MH, Kazempour D, Fischbach MA, Breitling R, Takano E, Weber T.

Nucleic Acids Res. 2013 Jul;41(Web Server issue):W204-12. doi: 10.1093/nar/gkt449.

20.

Design-based re-engineering of biosynthetic gene clusters: plug-and-play in practice.

Frasch HJ, Medema MH, Takano E, Breitling R.

Curr Opin Biotechnol. 2013 Dec;24(6):1144-50. doi: 10.1016/j.copbio.2013.03.006. Review.

PMID:
23540422

Supplemental Content

Loading ...
Support Center