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GoldenPiCS: a Golden Gate-derived modular cloning system for applied synthetic biology in the yeast Pichia pastoris.

Prielhofer R, Barrero JJ, Steuer S, Gassler T, Zahrl R, Baumann K, Sauer M, Mattanovich D, Gasser B, Marx H.

BMC Syst Biol. 2017 Dec 8;11(1):123. doi: 10.1186/s12918-017-0492-3.


Creation of Stable Heterothallic Strains of Komagataella phaffii Enables Dissection of Mating Gene Regulation.

Heistinger L, Gasser B, Mattanovich D.

Mol Cell Biol. 2017 Dec 29;38(2). pii: e00398-17. doi: 10.1128/MCB.00398-17. Print 2018 Jan 15.


Microbial organic acid production as carbon dioxide sink.

Steiger MG, Mattanovich D, Sauer M.

FEMS Microbiol Lett. 2017 Nov 15;364(21). doi: 10.1093/femsle/fnx212.


Systems biotechnology for protein production in Pichia pastoris.

Zahrl RJ, Peña DA, Mattanovich D, Gasser B.

FEMS Yeast Res. 2017 Nov 1;17(7). doi: 10.1093/femsyr/fox068.


Biomarkers allow detection of nutrient limitations and respective supplementation for elimination in Pichia pastoris fed-batch cultures.

Burgard J, Valli M, Graf AB, Gasser B, Mattanovich D.

Microb Cell Fact. 2017 Jul 11;16(1):117. doi: 10.1186/s12934-017-0730-9.


Transcriptional engineering of the glyceraldehyde-3-phosphate dehydrogenase promoter for improved heterologous protein production in Pichia pastoris.

Ata Ö, Prielhofer R, Gasser B, Mattanovich D, Çalık P.

Biotechnol Bioeng. 2017 Oct;114(10):2319-2327. doi: 10.1002/bit.26363. Epub 2017 Jul 27.


An efficient tool for metabolic pathway construction and gene integration for Aspergillus niger.

Sarkari P, Marx H, Blumhoff ML, Mattanovich D, Sauer M, Steiger MG.

Bioresour Technol. 2017 Dec;245(Pt B):1327-1333. doi: 10.1016/j.biortech.2017.05.004. Epub 2017 May 4.


Impact of glutathione metabolism on zinc homeostasis in Saccharomyces cerevisiae.

Steiger MG, Patzschke A, Holz C, Lang C, Causon T, Hann S, Mattanovich D, Sauer M.

FEMS Yeast Res. 2017 Jun 1;17(4). doi: 10.1093/femsyr/fox028.


Non-genetic impact factors on chronological lifespan and stress resistance of baker's yeast.

Sauer M, Mattanovich D.

Microb Cell. 2016 Apr 12;3(6):232-235. doi: 10.15698/mic2016.06.504.


Metabolomics of Pichia pastoris: impact of buffering conditions on the kinetics and nature of metabolite loss during quenching.

Mattanovich M, Russmayer H, Scharl-Hirsch T, Puxbaum V, Burgard J, Mattanovich D, Hann S.

FEMS Yeast Res. 2017 May 1;17(3). doi: 10.1093/femsyr/fox016.


Implications of evolutionary engineering for growth and recombinant protein production in methanol-based growth media in the yeast Pichia pastoris.

Moser JW, Prielhofer R, Gerner SM, Graf AB, Wilson IB, Mattanovich D, Dragosits M.

Microb Cell Fact. 2017 Mar 17;16(1):49. doi: 10.1186/s12934-017-0661-5.


Increased dosage of AOX1 promoter-regulated expression cassettes leads to transcription attenuation of the methanol metabolism in Pichia pastoris.

Cámara E, Landes N, Albiol J, Gasser B, Mattanovich D, Ferrer P.

Sci Rep. 2017 Mar 15;7:44302. doi: 10.1038/srep44302.


Disruption of genes involved in CORVET complex leads to enhanced secretion of heterologous carboxylesterase only in protease deficient Pichia pastoris.

Marsalek L, Gruber C, Altmann F, Aleschko M, Mattanovich D, Gasser B, Puxbaum V.

Biotechnol J. 2017 May;12(5). doi: 10.1002/biot.201600584. Epub 2017 Mar 30.


The vitamin-sensitive promoter PTHI11 enables pre-defined autonomous induction of recombinant protein production in Pichia pastoris.

Landes N, Gasser B, Vorauer-Uhl K, Lhota G, Mattanovich D, Maurer M.

Biotechnol Bioeng. 2016 Dec;113(12):2633-2643. doi: 10.1002/bit.26041. Epub 2016 Jul 8.


Functional inclusion bodies produced in the yeast Pichia pastoris.

Rueda F, Gasser B, Sánchez-Chardi A, Roldán M, Villegas S, Puxbaum V, Ferrer-Miralles N, Unzueta U, Vázquez E, Garcia-Fruitós E, Mattanovich D, Villaverde A.

Microb Cell Fact. 2016 Oct 1;15(1):166.


Curation of the genome annotation of Pichia pastoris (Komagataella phaffii) CBS7435 from gene level to protein function.

Valli M, Tatto NE, Peymann A, Gruber C, Landes N, Ekker H, Thallinger GG, Mattanovich D, Gasser B, Graf AB.

FEMS Yeast Res. 2016 Sep;16(6). pii: fow051. doi: 10.1093/femsyr/fow051. Epub 2016 Jul 6.


The bud tip is the cellular hot spot of protein secretion in yeasts.

Puxbaum V, Gasser B, Mattanovich D.

Appl Microbiol Biotechnol. 2016 Sep;100(18):8159-68. doi: 10.1007/s00253-016-7674-6. Epub 2016 Jun 23.


Pichia pastoris Exhibits High Viability and a Low Maintenance Energy Requirement at Near-Zero Specific Growth Rates.

Rebnegger C, Vos T, Graf AB, Valli M, Pronk JT, Daran-Lapujade P, Mattanovich D.

Appl Environ Microbiol. 2016 Jul 15;82(15):4570-83. doi: 10.1128/AEM.00638-16. Print 2016 Aug 1.


Complete genome sequence and transcriptome regulation of the pentose utilizing yeast Sugiyamaella lignohabitans.

Bellasio M, Peymann A, Steiger MG, Valli M, Sipiczki M, Sauer M, Graf AB, Marx H, Mattanovich D.

FEMS Yeast Res. 2016 Jun;16(4). pii: fow037. doi: 10.1093/femsyr/fow037. Epub 2016 Apr 17.


Corrigendum: Methylation of ribosomal RNA by NSUN5 is a conserved mechanism modulating organismal lifespan.

Schosserer M, Minois N, Angerer TB, Amring M, Dellago H, Harreither E, Calle-Perez A, Pircher A, Peter Gerstl M, Pfeifenberger S, Brandl C, Sonntagbauer M, Kriegner A, Linder A, Weinhäusel A, Mohr T, Steiger M, Mattanovich D, Rinnerthaler M, Karl T, Sharma S, Entian KD, Kos M, Breitenbach M, Wilson IB, Polacek N, Grillari-Voglauer R, Breitenbach-Koller L, Grillari J.

Nat Commun. 2016 May 11;7:11530. doi: 10.1038/ncomms11530. No abstract available.

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