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Items: 16


Biophysical and Functional Characterization of Rhesus Macaque IgG Subclasses.

Boesch AW, Osei-Owusu NY, Crowley AR, Chu TH, Chan YN, Weiner JA, Bharadwaj P, Hards R, Adamo ME, Gerber SA, Cocklin SL, Schmitz JE, Miles AR, Eckman JW, Belli AJ, Reimann KA, Ackerman ME.

Front Immunol. 2016 Dec 13;7:589. doi: 10.3389/fimmu.2016.00589. eCollection 2016 Dec 13.


Potency of a Human Monoclonal Antibody to Diphtheria Toxin Relative to Equine Diphtheria Anti-toxin in an Animal Model.

Smith H, Cheslock P, Leney M, Barton B, Molrine D.

Open Forum Infect Dis. 2015 Dec 9;2(Suppl 1):116. doi: 10.1093/ofid/ofv131.36. eCollection 2015 Dec 9. No abstract available.


Systemic administration of an HIV-1 broadly neutralizing dimeric IgA yields mucosal secretory IgA and virus neutralization.

Fouda GG, Eudailey J, Kunz EL, Amos JD, Liebl BE, Himes J, Boakye-Agyeman F, Beck K, Michaels AJ, Cohen-Wolkowiez M, Haynes BF, Reimann KA, Permar SR.

Mucosal Immunol. 2017 Jan;10(1):228-237. doi: 10.1038/mi.2016.32. Epub 2016 Apr 13.


Potency of a human monoclonal antibody to diphtheria toxin relative to equine diphtheria anti-toxin in a guinea pig intoxication model.

Smith HL, Cheslock P, Leney M, Barton B, Molrine DC.

Virulence. 2016 Aug 17;7(6):660-8. doi: 10.1080/21505594.2016.1171436. Epub 2016 Apr 12.


Chimeric 2C10R4 anti-CD40 antibody therapy is critical for long-term survival of GTKO.hCD46.hTBM pig-to-primate cardiac xenograft.

Mohiuddin MM, Singh AK, Corcoran PC, Thomas ML 3rd, Clark T, Lewis BG, Hoyt RF, Eckhaus M, Pierson RN 3rd, Belli AJ, Wolf E, Klymiuk N, Phelps C, Reimann KA, Ayares D, Horvath KA.

Nat Commun. 2016 Apr 5;7:11138. doi: 10.1038/ncomms11138.


Isolation of potent neutralizing antibodies from a survivor of the 2014 Ebola virus outbreak.

Bornholdt ZA, Turner HL, Murin CD, Li W, Sok D, Souders CA, Piper AE, Goff A, Shamblin JD, Wollen SE, Sprague TR, Fusco ML, Pommert KB, Cavacini LA, Smith HL, Klempner M, Reimann KA, Krauland E, Gerngross TU, Wittrup KD, Saphire EO, Burton DR, Glass PJ, Ward AB, Walker LM.

Science. 2016 Mar 4;351(6277):1078-83. doi: 10.1126/science.aad5788. Epub 2016 Feb 18.


Association of immune response to endothelial cell growth factor with early disseminated and late manifestations of Lyme disease but not posttreatment Lyme disease syndrome.

Tang KS, Klempner MS, Wormser GP, Marques AR, Alaedini A.

Clin Infect Dis. 2015 Dec 1;61(11):1703-6. doi: 10.1093/cid/civ638. Epub 2015 Jul 28.


Circulating Levels of sFlt1 Splice Variants as Predictive Markers for the Development of Preeclampsia.

Souders CA, Maynard SE, Yan J, Wang Y, Boatright NK, Sedan J, Balyozian D, Cheslock PS, Molrine DC, Simas TA.

Int J Mol Sci. 2015 Jun 2;16(6):12436-53. doi: 10.3390/ijms160612436.


A novel in vitro assay to predict neonatal Fc receptor-mediated human IgG half-life.

Souders CA, Nelson SC, Wang Y, Crowley AR, Klempner MS, Thomas W Jr.

MAbs. 2015;7(5):912-21. doi: 10.1080/19420862.2015.1054585.


Resolving self-association of a therapeutic antibody by formulation optimization and molecular approaches.

Casaz P, Boucher E, Wollacott R, Pierce BG, Rivera R, Sedic M, Ozturk S, Thomas WD Jr, Wang Y.

MAbs. 2014;6(6):1533-9. doi: 10.4161/19420862.2014.975658.


High-throughput sequencing analysis of post-liver transplantation HCV E2 glycoprotein evolution in the presence and absence of neutralizing monoclonal antibody.

Babcock GJ, Iyer S, Smith HL, Wang Y, Rowley K, Ambrosino DM, Zamore PD, Pierce BG, Molrine DC, Weng Z.

PLoS One. 2014 Jun 23;9(6):e100325. doi: 10.1371/journal.pone.0100325. eCollection 2014 Jun 23.


Analytical characterization of a monoclonal antibody therapeutic reveals a three-light chain species that is efficiently removed using hydrophobic interaction chromatography.

Wollacott RB, Casaz PL, Morin TJ, Zhu HL, Anderson RS, Babcock GJ, Que J, Thomas WD Jr, Ozturk SS.

MAbs. 2013 Nov-Dec;5(6):925-35. doi: 10.4161/mabs.26192. Epub 2013 Aug 19.


Identification of a human monoclonal antibody to replace equine diphtheria antitoxin for treatment of diphtheria intoxication.

Sevigny LM, Booth BJ, Rowley KJ, Leav BA, Cheslock PS, Garrity KA, Sloan SE, Thomas W Jr, Babcock GJ, Wang Y.

Infect Immun. 2013 Nov;81(11):3992-4000. doi: 10.1128/IAI.00462-13. Epub 2013 Aug 12.


Identification of human monoclonal antibodies specific for human SOD1 recognizing distinct epitopes and forms of SOD1.

Broering TJ, Wang H, Boatright NK, Wang Y, Baptista K, Shayan G, Garrity KA, Kayatekin C, Bosco DA, Matthews CR, Ambrosino DM, Xu Z, Babcock GJ.

PLoS One. 2013 Apr 17;8(4):e61210. doi: 10.1371/journal.pone.0061210. Print 2013.


Human monoclonal antibody HCV1 effectively prevents and treats HCV infection in chimpanzees.

Morin TJ, Broering TJ, Leav BA, Blair BM, Rowley KJ, Boucher EN, Wang Y, Cheslock PS, Knauber M, Olsen DB, Ludmerer SW, Szabo G, Finberg RW, Purcell RH, Lanford RE, Ambrosino DM, Molrine DC, Babcock GJ.

PLoS Pathog. 2012;8(8):e1002895. doi: 10.1371/journal.ppat.1002895. Epub 2012 Aug 30.


Identification and characterization of broadly neutralizing human monoclonal antibodies directed against the E2 envelope glycoprotein of hepatitis C virus.

Broering TJ, Garrity KA, Boatright NK, Sloan SE, Sandor F, Thomas WD Jr, Szabo G, Finberg RW, Ambrosino DM, Babcock GJ.

J Virol. 2009 Dec;83(23):12473-82. doi: 10.1128/JVI.01138-09. Epub 2009 Sep 16.

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