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Pharmacokinetics and pharmacodynamics of insulin glargine given in the evening as compared with in the morning in type 2 diabetes.

Porcellati F, Lucidi P, Cioli P, Candeloro P, Marinelli Andreoli A, Marzotti S, Ambrogi M, Bolli GB, Fanelli CG.

Diabetes Care. 2015 Mar;38(3):503-12. doi: 10.2337/dc14-0649. Epub 2014 Dec 18.


Glargine metabolism over 24 h following its subcutaneous injection in patients with type 2 diabetes mellitus: a dose-response study.

Lucidi P, Porcellati F, Candeloro P, Cioli P, Andreoli AM, Marzotti S, Schmidt R, Bolli GB, Fanelli CG.

Nutr Metab Cardiovasc Dis. 2014 Jul;24(7):709-16. doi: 10.1016/j.numecd.2014.02.008. Epub 2014 Feb 22.


Blood cell mitochondrial DNA content and premature ovarian aging.

Bonomi M, Somigliana E, Cacciatore C, Busnelli M, Rossetti R, Bonetti S, Paffoni A, Mari D, Ragni G, Persani L; Italian Network for the study of Ovarian Dysfunctions..

PLoS One. 2012;7(8):e42423. Epub 2012 Aug 3.


A novel variation in the AVP gene resulting in familial neurohypophyseal diabetes insipidus in a large Italian kindred.

Birkegaard C, Christensen JH, Falorni A, Marzotti S, Minarelli V, Gregersen N, Rittig S.

Pituitary. 2013 Jun;16(2):152-7. doi: 10.1007/s11102-012-0392-x.


Basal insulin and cardiovascular and other outcomes in dysglycemia.

ORIGIN Trial Investigators., Gerstein HC, Bosch J, Dagenais GR, Díaz R, Jung H, Maggioni AP, Pogue J, Probstfield J, Ramachandran A, Riddle MC, Rydén LE, Yusuf S.

N Engl J Med. 2012 Jul 26;367(4):319-28. doi: 10.1056/NEJMoa1203858. Epub 2012 Jun 11.


n-3 fatty acids and cardiovascular outcomes in patients with dysglycemia.

ORIGIN Trial Investigators., Bosch J, Gerstein HC, Dagenais GR, Díaz R, Dyal L, Jung H, Maggiono AP, Probstfield J, Ramachandran A, Riddle MC, Rydén LE, Yusuf S.

N Engl J Med. 2012 Jul 26;367(4):309-18. doi: 10.1056/NEJMoa1203859. Epub 2012 Jun 11.


BClI polymorphism of the glucocorticoid receptor gene is associated with increased obesity, impaired glucose metabolism and dyslipidaemia in patients with Addison's disease.

Giordano R, Marzotti S, Berardelli R, Karamouzis I, Brozzetti A, D'Angelo V, Mengozzi G, Mandrile G, Giachino D, Migliaretti G, Bini V, Falorni A, Ghigo E, Arvat E.

Clin Endocrinol (Oxf). 2012 Dec;77(6):863-70. doi: 10.1111/j.1365-2265.2012.04439.x.


Progressive decline of residual follicle pool after clinical diagnosis of autoimmune ovarian insufficiency.

Falorni A, Brozzetti A, Aglietti MC, Esposito R, Minarelli V, Morelli S, Sbroma Tomaro E, Marzotti S.

Clin Endocrinol (Oxf). 2012 Sep;77(3):453-8. doi: 10.1111/j.1365-2265.2012.04387.x.


Differential effects of adiposity on pharmacodynamics of basal insulins NPH, glargine, and detemir in type 2 diabetes mellitus.

Porcellati F, Lucidi P, Rossetti P, Candeloro P, Andreoli AM, Marzotti S, Cioli P, Bolli GB, Fanelli CG.

Diabetes Care. 2011 Dec;34(12):2521-3. doi: 10.2337/dc11-1064. Epub 2011 Oct 4.


Pharmacokinetics and pharmacodynamics of therapeutic doses of basal insulins NPH, glargine, and detemir after 1 week of daily administration at bedtime in type 2 diabetic subjects: a randomized cross-over study.

Lucidi P, Porcellati F, Rossetti P, Candeloro P, Cioli P, Marzotti S, Andreoli AM, Fede R, Bolli GB, Fanelli CG.

Diabetes Care. 2011 Jun;34(6):1312-4. doi: 10.2337/dc10-1911. Epub 2011 Apr 15.


Comparative pharmacodynamic and pharmacokinetic characteristics of subcutaneous insulin glulisine and insulin aspart prior to a standard meal in obese subjects with type 2 diabetes.

Bolli GB, Luzio S, Marzotti S, Porcellati F, Sert-Langeron C, Charbonnel B, Zair Y, Owens DR.

Diabetes Obes Metab. 2011 Mar;13(3):251-7. doi: 10.1111/j.1463-1326.2010.01343.x.


Primary ovarian insufficiency: autoimmune causes.

La Marca A, Brozzetti A, Sighinolfi G, Marzotti S, Volpe A, Falorni A.

Curr Opin Obstet Gynecol. 2010 Aug;22(4):277-82. doi: 10.1097/GCO.0b013e32833b6c70. Review.


Autoantibody responses in autoimmune ovarian insufficiency and in Addison's disease are IgG1 dominated and suggest a predominant, but not exclusive, Th1 type of response.

Brozzetti A, Marzotti S, La Torre D, Bacosi ML, Morelli S, Bini V, Ambrosi B, Giordano R, Perniola R, De Bellis A, Betterle C, Falorni A; Italian Addison Network..

Eur J Endocrinol. 2010 Aug;163(2):309-17. doi: 10.1530/EJE-10-0257. Epub 2010 May 24.


Hyperglycemia-induced platelet activation in type 2 diabetes is resistant to aspirin but not to a nitric oxide-donating agent.

Gresele P, Marzotti S, Guglielmini G, Momi S, Giannini S, Minuz P, Lucidi P, Bolli GB.

Diabetes Care. 2010 Jun;33(6):1262-8. doi: 10.2337/dc09-2013. Epub 2010 Mar 18.


Cytotoxic T lymphocyte antigen-4 Ala17 polymorphism is a genetic marker of autoimmune adrenal insufficiency: Italian association study and meta-analysis of European studies.

Brozzetti A, Marzotti S, Tortoioli C, Bini V, Giordano R, Dotta F, Betterle C, De Bellis A, Arnaldi G, Toscano V, Arvat E, Bellastella A, Mantero F, Falorni A; Italian Addison Network..

Eur J Endocrinol. 2010 Feb;162(2):361-9. doi: 10.1530/EJE-09-0618. Epub 2009 Nov 2.


Primary ovarian insufficiency due to steroidogenic cell autoimmunity is associated with a preserved pool of functioning follicles.

La Marca A, Marzotti S, Brozzetti A, Stabile G, Artenisio AC, Bini V, Giordano R, De Bellis A, Volpe A, Falorni A; Italian Addison Network..

J Clin Endocrinol Metab. 2009 Oct;94(10):3816-23. doi: 10.1210/jc.2009-0817. Epub 2009 Jul 21.


Metabolic and cardiovascular profile in patients with Addison's disease under conventional glucocorticoid replacement.

Giordano R, Marzotti S, Balbo M, Romagnoli S, Marinazzo E, Berardelli R, Migliaretti G, Benso A, Falorni A, Ghigo E, Arvat E.

J Endocrinol Invest. 2009 Dec;32(11):917-23. doi: 10.3275/6437. Epub 2009 Jul 20.


A large-scale association study to assess the impact of known variants of the human INHA gene on premature ovarian failure.

Corre T, Schuettler J, Bione S, Marozzi A, Persani L, Rossetti R, Torricelli F, Giotti I, Vogt P, Toniolo D; Italian Network for the study of Ovarian Dysfunctions..

Hum Reprod. 2009 Aug;24(8):2023-8. doi: 10.1093/humrep/dep090. Epub 2009 Apr 10.


High serum inhibin concentration discriminates autoimmune oophoritis from other forms of primary ovarian insufficiency.

Tsigkou A, Marzotti S, Borges L, Brozzetti A, Reis F, Candeloro P, Luisa Bacosi M, Bini V, Petraglia F, Falorni A.

J Clin Endocrinol Metab. 2008 Apr;93(4):1263-9. doi: 10.1210/jc.2007-1675. Epub 2008 Jan 22.


Comparison of pharmacokinetics and dynamics of the long-acting insulin analogs glargine and detemir at steady state in type 1 diabetes: a double-blind, randomized, crossover study.

Porcellati F, Rossetti P, Busciantella NR, Marzotti S, Lucidi P, Luzio S, Owens DR, Bolli GB, Fanelli CG.

Diabetes Care. 2007 Oct;30(10):2447-52. Epub 2007 Jul 10. Erratum in: Diabetes Care. 2008 Jan;31(1):188.


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