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Items: 1 to 20 of 26


Autophagy regulates Selumetinib (AZD6244) induced-apoptosis in colorectal cancer cells.

Grasso S, Pereira GJS, Palmeira-Dos-Santos C, Calgarotto AK, Martínez-Lacaci I, Ferragut JA, Smaili SS, Bincoletto C.

Eur J Med Chem. 2016 Oct 21;122:611-618. doi: 10.1016/j.ejmech.2016.06.043. Epub 2016 Jul 9.


HGUE-C-1 is an atypical and novel colon carcinoma cell line.

Grasso S, Martínez-Lacaci I, Barberá VM, Castillejo A, Soto JL, Gallego-Plazas J, López-Riquelme N, García-Morales P, Mata-Balaguer T, Ferragut JA, Saceda M.

BMC Cancer. 2015 Apr 8;15:240. doi: 10.1186/s12885-015-1183-3.


Association of a characteristic membrane pattern of annexin A2 with high invasiveness and nodal status in colon adenocarcinoma.

Tristante E, Martínez CM, Jiménez S, Mora L, Carballo F, Martínez-Lacaci I, de Torre-Minguela C.

Transl Res. 2015 Aug;166(2):196-206. doi: 10.1016/j.trsl.2015.02.006. Epub 2015 Feb 28.


Comparative Study of 17-AAG and NVP-AUY922 in Pancreatic and Colorectal Cancer Cells: Are There Common Determinants of Sensitivity?

Mayor-López L, Tristante E, Carballo-Santana M, Carrasco-García E, Grasso S, García-Morales P, Saceda M, Luján J, García-Solano J, Carballo F, de Torre C, Martínez-Lacaci I.

Transl Oncol. 2014 Oct 24;7(5):590-604. doi: 10.1016/j.tranon.2014.08.001. eCollection 2014 Oct.


Resistance to Selumetinib (AZD6244) in colorectal cancer cell lines is mediated by p70S6K and RPS6 activation.

Grasso S, Tristante E, Saceda M, Carbonell P, Mayor-López L, Carballo-Santana M, Carrasco-García E, Rocamora-Reverte L, García-Morales P, Carballo F, Ferragut JA, Martínez-Lacaci I.

Neoplasia. 2014 Oct 23;16(10):845-60. doi: 10.1016/j.neo.2014.08.011. eCollection 2014 Oct.


Role of receptor tyrosine kinases and their ligands in glioblastoma.

Carrasco-García E, Saceda M, Martínez-Lacaci I.

Cells. 2014 Apr 4;3(2):199-235. doi: 10.3390/cells3020199.


Dual regulation of P-glycoprotein expression by trichostatin A in cancer cell lines.

Balaguer TM, Gómez-Martínez A, García-Morales P, Lacueva J, Calpena R, Reverte LR, Riquelme NL, Martinez-Lacaci I, Ferragut JA, Saceda M.

BMC Mol Biol. 2012 Jul 30;13:25. doi: 10.1186/1471-2199-13-25.


Small tyrosine kinase inhibitors interrupt EGFR signaling by interacting with erbB3 and erbB4 in glioblastoma cell lines.

Carrasco-García E, Saceda M, Grasso S, Rocamora-Reverte L, Conde M, Gómez-Martínez A, García-Morales P, Ferragut JA, Martínez-Lacaci I.

Exp Cell Res. 2011 Jun 10;317(10):1476-89. doi: 10.1016/j.yexcr.2011.03.015. Epub 2011 Apr 1.


Protein kinase C-alpha antagonizes apoptosis induction by histone deacetylase inhibitors in multidrug resistant leukaemia cells.

Castro-Galache MD, Menéndez-Gutiérrez MP, Carrasco Garcia E, Garcia-Morales P, Martinez-Lacaci I, Saceda M, Ferragut JA.

Int J Biochem Cell Biol. 2007;39(10):1877-85. Epub 2007 May 21.


Inhibition of Hsp90 function by ansamycins causes downregulation of cdc2 and cdc25c and G(2)/M arrest in glioblastoma cell lines.

García-Morales P, Carrasco-García E, Ruiz-Rico P, Martínez-Mira R, Menéndez-Gutiérrez MP, Ferragut JA, Saceda M, Martínez-Lacaci I.

Oncogene. 2007 Nov 8;26(51):7185-93. Epub 2007 May 21.


Tumour cells resistance in cancer therapy.

Martínez-Lacaci I, García Morales P, Soto JL, Saceda M.

Clin Transl Oncol. 2007 Jan;9(1):13-20. Review.


Cyclin D3 is down-regulated by rapamycin in HER-2-overexpressing breast cancer cells.

García-Morales P, Hernando E, Carrasco-García E, Menéndez-Gutierrez MP, Saceda M, Martínez-Lacaci I.

Mol Cancer Ther. 2006 Sep;5(9):2172-81.


Histone deacetylase inhibitors induced caspase-independent apoptosis in human pancreatic adenocarcinoma cell lines.

García-Morales P, Gómez-Martínez A, Carrato A, Martínez-Lacaci I, Barberá VM, Soto JL, Carrasco-García E, Menéndez-Gutierrez MP, Castro-Galache MD, Ferragut JA, Saceda M.

Mol Cancer Ther. 2005 Aug;4(8):1222-30.


Regulation of heparin-binding EGF-like growth factor expression in Ha-ras transformed human mammary epithelial cells.

Martínez-Lacaci I, De Santis M, Kannan S, Bianco C, Kim N, Wallace-Jones B, Wechselberger C, Ebert AD, Salomon DS.

J Cell Physiol. 2001 Feb;186(2):233-42.


RAS transformation causes sustained activation of epidermal growth factor receptor and elevation of mitogen-activated protein kinase in human mammary epithelial cells.

Martínez-Lacaci I, Kannan S, De Santis M, Bianco C, Kim N, Wallace-Jones B, Ebert AD, Wechselberger C, Salomon DS.

Int J Cancer. 2000 Oct 1;88(1):44-52.


Cripto-1-induced increase in vimentin expression is associated with enhanced migration of human Caski cervical carcinoma cells.

Ebert AD, Wechselberger C, Nees M, Clair T, Schaller G, Martinez-Lacaci I, Wallace-Jones B, Bianco C, Weitzel HK, Salomon DS.

Exp Cell Res. 2000 May 25;257(1):223-9.


Cripto-1 induces apoptosis in HC-11 mouse mammary epithelial cells.

De Santis ML, Martinez-Lacaci I, Bianco C, Seno M, Wallace-Jones B, Kim N, Ebert A, Wechselberger C, Salomon DS.

Cell Death Differ. 2000 Feb;7(2):189-96.


Expression and function of EGF-related peptides and their receptors in gynecological cancer--from basic science to therapy.

Ebert AD, Wechselberger C, Martinez-Lacaci I, Bianco C, Weitzel HK, Salomon DS.

J Recept Signal Transduct Res. 2000 Jan;20(1):1-46. Review.


Cripto-1 induces phosphatidylinositol 3'-kinase-dependent phosphorylation of AKT and glycogen synthase kinase 3beta in human cervical carcinoma cells.

Ebert AD, Wechselberger C, Frank S, Wallace-Jones B, Seno M, Martinez-Lacaci I, Bianco C, De Santis M, Weitzel HK, Salomon DS.

Cancer Res. 1999 Sep 15;59(18):4502-5.


Cripto-1 indirectly stimulates the tyrosine phosphorylation of erb B-4 through a novel receptor.

Bianco C, Kannan S, De Santis M, Seno M, Tang CK, Martinez-Lacaci I, Kim N, Wallace-Jones B, Lippman ME, Ebert AD, Wechselberger C, Salomon DS.

J Biol Chem. 1999 Mar 26;274(13):8624-9.

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