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Military Supplement: Assessment of Coagulation Homeostasis in Blunt, Penetrating, and Thermal Trauma: Guidance for a Multi-Center Systems Biology Approach.

Shupp JW, Brummel-Ziedins KE, Cohen MJ, Freeman K, Hammamieh R, Mudunuri US, Orfeo T, Moffatt LT, Brownstein BH, Mann KG, Jett M, Pusateri AE.

Shock. 2018 Oct 18. doi: 10.1097/SHK.0000000000001275. [Epub ahead of print]


Issues complicating precision dosing for factor VIII prophylaxis.

Valentino LA, Turecek PL, Gritsch H, Butenas S, Mann KG.

Transfus Apher Sci. 2018 Aug;57(4):472-479. doi: 10.1016/j.transci.2018.07.007. Epub 2018 Aug 21. Review.


Continuous thrombin generation in whole blood: New applications for assessing activators and inhibitors of coagulation.

Prior SM, Mann KG, Freeman K, Butenas S.

Anal Biochem. 2018 Jun 15;551:19-25. doi: 10.1016/j.ab.2018.05.005. Epub 2018 May 7.


Hemodilution and Endothelial Cell Regulation of Whole Blood Coagulation.

Orfeo T, Gissel M, Haynes LM, Pusateri A, Mann KG, Brummel-Ziedins KE.

Mil Med. 2018 Mar 1;183(suppl_1):175-182. doi: 10.1093/milmed/usx180.


Microparticles formed during storage of red blood cell units support thrombin generation.

Bouchard BA, Orfeo T, Keith HN, Lavoie EM, Gissel M, Fung M, Mann KG.

J Trauma Acute Care Surg. 2018 Apr;84(4):598-605. doi: 10.1097/TA.0000000000001759.


Analysis of factor XIa, factor IXa and tissue factor activity in burn patients.

Shupp JW, Prior SM, Jo DY, Moffatt LT, Mann KG, Butenas S.

Burns. 2018 Mar;44(2):436-444. doi: 10.1016/j.burns.2017.08.003. Epub 2017 Oct 9.


Probing the Dynamics of Clot-Bound Thrombin at Venous Shear Rates.

Haynes LM, Orfeo T, Mann KG, Everse SJ, Brummel-Ziedins KE.

Biophys J. 2017 Apr 25;112(8):1634-1644. doi: 10.1016/j.bpj.2017.03.002.


Effects of an acidic environment on coagulation dynamics.

Gissel M, Brummel-Ziedins KE, Butenas S, Pusateri AE, Mann KG, Orfeo T.

J Thromb Haemost. 2016 Oct;14(10):2001-2010. doi: 10.1111/jth.13418. Epub 2016 Sep 12.


Thrombin generation and cell-dependent hypercoagulability in sickle cell disease.

Whelihan MF, Lim MY, Mooberry MJ, Piegore MG, Ilich A, Wogu A, Cai J, Monroe DM, Ataga KI, Mann KG, Key NS.

J Thromb Haemost. 2016 Oct;14(10):1941-1952. doi: 10.1111/jth.13416. Epub 2016 Aug 31.


In-depth analysis of clotting dynamics in burn patients.

Tejiram S, Brummel-Ziedins KE, Orfeo T, Mete M, Desale S, Hamilton BN, Moffatt LT, Mann KG, Tracy RP, Shupp JW.

J Surg Res. 2016 May 15;202(2):341-51. doi: 10.1016/j.jss.2016.01.006. Epub 2016 Jan 12.


Activation, activity and inactivation of factor VIII in factor VIII products.

Orfeo T, Elsman R, Gissel M, Mann KG, Butenas S.

Haemophilia. 2016 May;22(3):462-73. doi: 10.1111/hae.12872. Epub 2016 Jan 29.


TACTIC: Trans-Agency Consortium for Trauma-Induced Coagulopathy.

Mann KG, Freeman K.

J Thromb Haemost. 2015 Jun;13 Suppl 1:S63-71. doi: 10.1111/jth.12981. Review.


The effect of corn trypsin inhibitor and inhibiting antibodies for FXIa and FXIIa on coagulation of plasma and whole blood: comment.

Butenas S, Mann KG.

J Thromb Haemost. 2015 Mar;13(3):487-8. doi: 10.1111/jth.12812. Epub 2015 Jan 14. No abstract available.


Why does aspirin decrease the risk of venous thromboembolism? On old and novel antithrombotic effects of acetyl salicylic acid.

Undas A, Brummel-Ziedins K, Mann KG.

J Thromb Haemost. 2014 Nov;12(11):1776-87. doi: 10.1111/jth.12728. Epub 2014 Oct 15. Review.


Platelets do not express the oxidized or reduced forms of tissue factor.

Bouchard BA, Gissel MT, Whelihan MF, Mann KG, Butenas S.

Biochim Biophys Acta. 2014 Mar;1840(3):1188-93. doi: 10.1016/j.bbagen.2013.11.024. Epub 2013 Dec 19.


Anticoagulant effects of statins and their clinical implications.

Undas A, Brummel-Ziedins KE, Mann KG.

Thromb Haemost. 2014 Mar 3;111(3):392-400. doi: 10.1160/TH13-08-0720. Epub 2013 Nov 28. Review.


Modeling thrombin generation: plasma composition based approach.

Brummel-Ziedins KE, Everse SJ, Mann KG, Orfeo T.

J Thromb Thrombolysis. 2014 Jan;37(1):32-44. doi: 10.1007/s11239-013-1006-9. Review.


The contribution of red blood cells to thrombin generation in sickle cell disease: meizothrombin generation on sickled red blood cells.

Whelihan MF, Mooberry MJ, Zachary V, Bradford RL, Ataga KI, Mann KG, Key NS.

J Thromb Haemost. 2013 Dec;11(12):2187-9. doi: 10.1111/jth.12423. No abstract available.


The nature of lipopolysaccharide-stimulated monocyte tissue factor activity.

Butenas S, Gissel M, Krudysz-Amblo J, Mann KG.

Blood Coagul Fibrinolysis. 2013 Sep 16. [Epub ahead of print]


Disulfide reduction abolishes tissue factor cofactor function.

Krudysz-Amblo J, Jennings ME 2nd, Knight T, Matthews DE, Mann KG, Butenas S.

Biochim Biophys Acta. 2013 Jun;1830(6):3489-96. doi: 10.1016/j.bbagen.2013.02.013. Epub 2013 Feb 20.

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