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Items: 19

1.

Resistance to malaria through structural variation of red blood cell invasion receptors.

Leffler EM, Band G, Busby GBJ, Kivinen K, Le QS, Clarke GM, Bojang KA, Conway DJ, Jallow M, Sisay-Joof F, Bougouma EC, Mangano VD, Modiano D, Sirima SB, Achidi E, Apinjoh TO, Marsh K, Ndila CM, Peshu N, Williams TN, Drakeley C, Manjurano A, Reyburn H, Riley E, Kachala D, Molyneux M, Nyirongo V, Taylor T, Thornton N, Tilley L, Grimsley S, Drury E, Stalker J, Cornelius V, Hubbart C, Jeffreys AE, Rowlands K, Rockett KA, Spencer CCA, Kwiatkowski DP; Malaria Genomic Epidemiology Network.

Science. 2017 Jun 16;356(6343). pii: eaam6393. doi: 10.1126/science.aam6393. Epub 2017 May 18.

PMID:
28522690
2.

Characterisation of the opposing effects of G6PD deficiency on cerebral malaria and severe malarial anaemia.

Clarke GM, Rockett K, Kivinen K, Hubbart C, Jeffreys AE, Rowlands K, Jallow M, Conway DJ, Bojang KA, Pinder M, Usen S, Sisay-Joof F, Sirugo G, Toure O, Thera MA, Konate S, Sissoko S, Niangaly A, Poudiougou B, Mangano VD, Bougouma EC, Sirima SB, Modiano D, Amenga-Etego LN, Ghansah A, Koram KA, Wilson MD, Enimil A, Evans J, Amodu OK, Olaniyan S, Apinjoh T, Mugri R, Ndi A, Ndila CM, Uyoga S, Macharia A, Peshu N, Williams TN, Manjurano A, Sepúlveda N, Clark TG, Riley E, Drakeley C, Reyburn H, Nyirongo V, Kachala D, Molyneux M, Dunstan SJ, Phu NH, Quyen NN, Thai CQ, Hien TT, Manning L, Laman M, Siba P, Karunajeewa H, Allen S, Allen A, Davis TM, Michon P, Mueller I, Molloy SF, Campino S, Kerasidou A, Cornelius VJ, Hart L, Shah SS, Band G, Spencer CC, Agbenyega T, Achidi E, Doumbo OK, Farrar J, Marsh K, Taylor T, Kwiatkowski DP; MalariaGEN Consortium.

Elife. 2017 Jan 9;6. pii: e15085. doi: 10.7554/eLife.15085.

3.

Admixture into and within sub-Saharan Africa.

Busby GB, Band G, Si Le Q, Jallow M, Bougama E, Mangano VD, Amenga-Etego LN, Enimil A, Apinjoh T, Ndila CM, Manjurano A, Nyirongo V, Doumba O, Rockett KA, Kwiatkowski DP, Spencer CC; Malaria Genomic Epidemiology Network.

Elife. 2016 Jun 21;5. pii: e15266. doi: 10.7554/eLife.15266.

4.

Glucose-6-phosphate dehydrogenase deficiency and the risk of malaria and other diseases in children in Kenya: a case-control and a cohort study.

Uyoga S, Ndila CM, Macharia AW, Nyutu G, Shah S, Peshu N, Clarke GM, Kwiatkowski DP, Rockett KA, Williams TN; MalariaGEN Consortium.

Lancet Haematol. 2015 Oct;2(10):e437-44. doi: 10.1016/S2352-3026(15)00152-0. Epub 2015 Sep 22.

5.

A novel locus of resistance to severe malaria in a region of ancient balancing selection.

Malaria Genomic Epidemiology Network, Band G, Rockett KA, Spencer CC, Kwiatkowski DP.

Nature. 2015 Oct 8;526(7572):253-7. doi: 10.1038/nature15390. Epub 2015 Sep 30.

6.

Genetic determinants of anti-malarial acquired immunity in a large multi-centre study.

Shelton JM, Corran P, Risley P, Silva N, Hubbart C, Jeffreys A, Rowlands K, Craik R, Cornelius V, Hensmann M, Molloy S, Sepulveda N, Clark TG, Band G, Clarke GM, Spencer CC, Kerasidou A, Campino S, Auburn S, Tall A, Ly AB, Mercereau-Puijalon O, Sakuntabhai A, Djimdé A, Maiga B, Touré O, Doumbo OK, Dolo A, Troye-Blomberg M, Mangano VD, Verra F, Modiano D, Bougouma E, Sirima SB, Ibrahim M, Hussain A, Eid N, Elzein A, Mohammed H, Elhassan A, Elhassan I, Williams TN, Ndila C, Macharia A, Marsh K, Manjurano A, Reyburn H, Lemnge M, Ishengoma D, Carter R, Karunaweera N, Fernando D, Dewasurendra R, Drakeley CJ, Riley EM, Kwiatkowski DP, Rockett KA; MalariaGEN Consortium.

Malar J. 2015 Aug 28;14:333. doi: 10.1186/s12936-015-0833-x.

7.

Novel Insights Into the Protective Role of Hemoglobin S and C Against Plasmodium falciparum Parasitemia.

Mangano VD, Kabore Y, Bougouma EC, Verra F, Sepulveda N, Bisseye C, Santolamazza F, Avellino P, Tiono AB, Diarra A, Nebie I, Rockett KA, Sirima SB, Modiano D; MalariaGEN Consortium.

J Infect Dis. 2015 Aug 15;212(4):626-34. doi: 10.1093/infdis/jiv098. Epub 2015 Feb 23.

8.

Host genetics and parasitic infections.

Mangano VD, Modiano D.

Clin Microbiol Infect. 2014 Dec;20(12):1265-75. doi: 10.1111/1469-0691.12793. Epub 2014 Dec 14. Review.

9.

Reappraisal of known malaria resistance loci in a large multicenter study.

Malaria Genomic Epidemiology Network; Malaria Genomic Epidemiology Network.

Nat Genet. 2014 Nov;46(11):1197-204. doi: 10.1038/ng.3107. Epub 2014 Sep 28.

10.

An evolutionary perspective of how infection drives human genome diversity: the case of malaria.

Mangano VD, Modiano D.

Curr Opin Immunol. 2014 Oct;30:39-47. doi: 10.1016/j.coi.2014.06.004. Epub 2014 Jul 1. Review.

PMID:
24996199
11.

Wide cross-reactivity between Anopheles gambiae and Anopheles funestus SG6 salivary proteins supports exploitation of gSG6 as a marker of human exposure to major malaria vectors in tropical Africa.

Rizzo C, Ronca R, Fiorentino G, Mangano VD, Sirima SB, Nèbiè I, Petrarca V, Modiano D, Arcà B.

Malar J. 2011 Jul 27;10:206. doi: 10.1186/1475-2875-10-206.

12.

HLA-DRB1 and -DQB1 loci in three west African ethnic groups: genetic relationship with sub-Saharan African and European populations.

Lulli P, Mangano VD, Onori A, Batini C, Luoni G, Sirima BS, Nebie I, Chessa L, Petrarca V, Modiano D.

Hum Immunol. 2009 Nov;70(11):903-9. doi: 10.1016/j.humimm.2009.07.025. Epub 2009 Aug 5.

PMID:
19664674
13.

Genome-wide and fine-resolution association analysis of malaria in West Africa.

Jallow M, Teo YY, Small KS, Rockett KA, Deloukas P, Clark TG, Kivinen K, Bojang KA, Conway DJ, Pinder M, Sirugo G, Sisay-Joof F, Usen S, Auburn S, Bumpstead SJ, Campino S, Coffey A, Dunham A, Fry AE, Green A, Gwilliam R, Hunt SE, Inouye M, Jeffreys AE, Mendy A, Palotie A, Potter S, Ragoussis J, Rogers J, Rowlands K, Somaskantharajah E, Whittaker P, Widden C, Donnelly P, Howie B, Marchini J, Morris A, SanJoaquin M, Achidi EA, Agbenyega T, Allen A, Amodu O, Corran P, Djimde A, Dolo A, Doumbo OK, Drakeley C, Dunstan S, Evans J, Farrar J, Fernando D, Hien TT, Horstmann RD, Ibrahim M, Karunaweera N, Kokwaro G, Koram KA, Lemnge M, Makani J, Marsh K, Michon P, Modiano D, Molyneux ME, Mueller I, Parker M, Peshu N, Plowe CV, Puijalon O, Reeder J, Reyburn H, Riley EM, Sakuntabhai A, Singhasivanon P, Sirima S, Tall A, Taylor TE, Thera M, Troye-Blomberg M, Williams TN, Wilson M, Kwiatkowski DP; Wellcome Trust Case Control Consortium; Malaria Genomic Epidemiology Network.

Nat Genet. 2009 Jun;41(6):657-65. doi: 10.1038/ng.388. Epub 2009 May 24.

14.

Genetics of susceptibility to Plasmodium falciparum: from classical malaria resistance genes towards genome-wide association studies.

Verra F, Mangano VD, Modiano D.

Parasite Immunol. 2009 May;31(5):234-53. doi: 10.1111/j.1365-3024.2009.01106.x. Review.

15.

Lack of association of interferon regulatory factor 1 with severe malaria in affected child-parental trio studies across three African populations.

Mangano VD, Clark TG, Auburn S, Campino S, Diakite M, Fry AE, Green A, Richardson A, Jallow M, Sisay-Joof F, Pinder M, Griffiths MJ, Newton C, Peshu N, Williams TN, Marsh K, Molyneux ME, Taylor TE, Modiano D, Kwiatkowski DP, Rockett KA.

PLoS One. 2009;4(1):e4206. doi: 10.1371/journal.pone.0004206. Epub 2009 Jan 15.

16.

Validating discovered Cis-acting regulatory genetic variants: application of an allele specific expression approach to HapMap populations.

Campino S, Forton J, Raj S, Mohr B, Auburn S, Fry A, Mangano VD, Vandiedonck C, Richardson A, Rockett K, Clark TG, Kwiatkowski DP.

PLoS One. 2008;3(12):e4105. doi: 10.1371/journal.pone.0004105. Epub 2008 Dec 31.

17.

A global network for investigating the genomic epidemiology of malaria.

Malaria Genomic Epidemiology Network.

Nature. 2008 Dec 11;456(7223):732-7. doi: 10.1038/nature07632.

18.

Interferon regulatory factor-1 polymorphisms are associated with the control of Plasmodium falciparum infection.

Mangano VD, Luoni G, Rockett KA, Sirima BS, Konaté A, Forton J, Clark TG, Bancone G, Sadighi Akha E, Kwiatkowski DP, Modiano D.

Genes Immun. 2008 Mar;9(2):122-9. doi: 10.1038/sj.gene.6364456. Epub 2008 Jan 17. Erratum in: Genes Immun. 2008 Jul;9(5):482. Akha, E S [corrected to Sadighi Akha, E].

19.

Functional deficit of T regulatory cells in Fulani, an ethnic group with low susceptibility to Plasmodium falciparum malaria.

Torcia MG, Santarlasci V, Cosmi L, Clemente A, Maggi L, Mangano VD, Verra F, Bancone G, Nebie I, Sirima BS, Liotta F, Frosali F, Angeli R, Severini C, Sannella AR, Bonini P, Lucibello M, Maggi E, Garaci E, Coluzzi M, Cozzolino F, Annunziato F, Romagnani S, Modiano D.

Proc Natl Acad Sci U S A. 2008 Jan 15;105(2):646-51. doi: 10.1073/pnas.0709969105. Epub 2008 Jan 3.

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