Sort by
Items per page

Send to

Choose Destination

Search results

Items: 1 to 20 of 76


Gender-specific expression of ATP-binding cassette (Abc) transporters and cytoprotective genes in mouse choroid plexus.

Flores K, Manautou JE, Renfro JL.

Toxicology. 2017 Jul 1;386:84-92. doi: 10.1016/j.tox.2017.05.019. Epub 2017 Jun 3.


From hepatoprotection models to new therapeutic modalities for treating liver diseases: a personal perspective.

Rudraiah S, Manautou JE.

Version 2. F1000Res. 2016 Jul 14 [revised 2016 Jul 1];5. pii: F1000 Faculty Rev-1698. doi: 10.12688/f1000research.8609.2. eCollection 2016. Review.


Acetaminophen Attenuates House Dust Mite-Induced Allergic Airway Disease in Mice.

Smith GJ, Thrall RS, Cloutier MM, Manautou JE, Morris JB.

J Pharmacol Exp Ther. 2016 Sep;358(3):569-79. doi: 10.1124/jpet.116.233684. Epub 2016 Jul 11.


The trypanocidal benznidazole promotes adaptive response to oxidative injury: Involvement of the nuclear factor-erythroid 2-related factor-2 (Nrf2) and multidrug resistance associated protein 2 (MRP2).

Rigalli JP, Perdomo VG, Ciriaci N, Francés DE, Ronco MT, Bataille AM, Ghanem CI, Ruiz ML, Manautou JE, Catania VA.

Toxicol Appl Pharmacol. 2016 Aug 1;304:90-8. doi: 10.1016/j.taap.2016.05.007. Epub 2016 May 12.


Reduced in vivo toxicity of doxorubicin by encapsulation in cholesterol-containing self-assembled nanoparticles.

Gonzalez-Fajardo L, Mahajan LH, Ndaya D, Hargrove D, Manautou JE, Liang BT, Chen MH, Kasi RM, Lu X.

Pharmacol Res. 2016 May;107:93-101. doi: 10.1016/j.phrs.2016.03.006. Epub 2016 Mar 11.


Acetaminophen from liver to brain: New insights into drug pharmacological action and toxicity.

Ghanem CI, Pérez MJ, Manautou JE, Mottino AD.

Pharmacol Res. 2016 Jul;109:119-31. doi: 10.1016/j.phrs.2016.02.020. Epub 2016 Feb 26. Review.


Elucidation of the Mechanisms through Which the Reactive Metabolite Diclofenac Acyl Glucuronide Can Mediate Toxicity.

Scialis RJ, Manautou JE.

J Pharmacol Exp Ther. 2016 Apr;357(1):167-76. doi: 10.1124/jpet.115.230755. Epub 2016 Feb 11.


Enhanced hepatotoxicity by acetaminophen in Vanin-1 knockout mice is associated with deficient proliferative and immune responses.

Ferreira DW, Goedken MJ, Rommelaere S, Chasson L, Galland F, Naquet P, Manautou JE.

Biochim Biophys Acta. 2016 Apr;1862(4):662-9. doi: 10.1016/j.bbadis.2016.02.001. Epub 2016 Feb 2.


Green tea extract provides extensive Nrf2-independent protection against lipid accumulation and NFκB pro- inflammatory responses during nonalcoholic steatohepatitis in mice fed a high-fat diet.

Li J, Sapper TN, Mah E, Rudraiah S, Schill KE, Chitchumroonchokchai C, Moller MV, McDonald JD, Rohrer PR, Manautou JE, Bruno RS.

Mol Nutr Food Res. 2016 Apr;60(4):858-70. doi: 10.1002/mnfr.201500814. Epub 2016 Feb 18.


Oxidative stress-responsive transcription factor NRF2 is not indispensable for the human hepatic Flavin-containing monooxygenase-3 (FMO3) gene expression in HepG2 cells.

Rudraiah S, Gu X, Hines RN, Manautou JE.

Toxicol In Vitro. 2016 Mar;31:54-9. doi: 10.1016/j.tiv.2015.11.016. Epub 2015 Nov 23.


Influence of Vanin-1 and Catalytic Products in Liver During Normal and Oxidative Stress Conditions.

Ferreira DW, Naquet P, Manautou JE.

Curr Med Chem. 2015;22(20):2407-16. Review.


Effects of Acetaminophen on Oxidant and Irritant Respiratory Tract Responses to Environmental Tobacco Smoke in Female Mice.

Smith GJ, Cichocki JA, Doughty BJ, Manautou JE, Jordt SE, Morris JB.

Environ Health Perspect. 2016 May;124(5):642-50. doi: 10.1289/ehp.1509851. Epub 2015 Oct 9.


Antioxidant fractions of Khaya grandifoliola C.DC. and Entada africana Guill. et Perr. induce nuclear translocation of Nrf2 in HC-04 cells.

Njayou FN, Amougou AM, Fouemene Tsayem R, Njikam Manjia J, Rudraiah S, Bradley B, Manautou JE, Fewou Moundipa P.

Cell Stress Chaperones. 2015 Nov;20(6):991-1000. doi: 10.1007/s12192-015-0628-6. Epub 2015 Aug 14.


Multidrug Resistance-Associated Protein 3 Plays an Important Role in Protection against Acute Toxicity of Diclofenac.

Scialis RJ, Csanaky IL, Goedken MJ, Manautou JE.

Drug Metab Dispos. 2015 Jul;43(7):944-50. doi: 10.1124/dmd.114.061705. Epub 2015 Apr 20.


Altered regulation of hepatic efflux transporters disrupts acetaminophen disposition in pediatric nonalcoholic steatohepatitis.

Canet MJ, Merrell MD, Hardwick RN, Bataille AM, Campion SN, Ferreira DW, Xanthakos SA, Manautou JE, A-Kader HH, Erickson RP, Cherrington NJ.

Drug Metab Dispos. 2015 Jun;43(6):829-35. doi: 10.1124/dmd.114.062703. Epub 2015 Mar 18.


Role of nuclear factor-erythroid 2-related factor 2 (Nrf2) in the transcriptional regulation of brain ABC transporters during acute acetaminophen (APAP) intoxication in mice.

Ghanem CI, Rudraiah S, Bataille AM, Vigo MB, Goedken MJ, Manautou JE.

Biochem Pharmacol. 2015 Apr 1;94(3):203-11. doi: 10.1016/j.bcp.2015.01.013. Epub 2015 Feb 7.


Differential Fmo3 gene expression in various liver injury models involving hepatic oxidative stress in mice.

Rudraiah S, Moscovitz JE, Donepudi AC, Campion SN, Slitt AL, Aleksunes LM, Manautou JE.

Toxicology. 2014 Nov 5;325:85-95. doi: 10.1016/j.tox.2014.08.013. Epub 2014 Sep 2.


Is nuclear factor erythroid 2-related factor 2 responsible for sex differences in susceptibility to acetaminophen-induced hepatotoxicity in mice?

Rohrer PR, Rudraiah S, Goedken MJ, Manautou JE.

Drug Metab Dispos. 2014 Oct;42(10):1663-74. doi: 10.1124/dmd.114.059006. Epub 2014 Aug 4.


Tolerance to acetaminophen hepatotoxicity in the mouse model of autoprotection is associated with induction of flavin-containing monooxygenase-3 (FMO3) in hepatocytes.

Rudraiah S, Rohrer PR, Gurevich I, Goedken MJ, Rasmussen T, Hines RN, Manautou JE.

Toxicol Sci. 2014 Sep;141(1):263-77. doi: 10.1093/toxsci/kfu124. Epub 2014 Jun 27.


Transgenic expression of the human MRP2 transporter reduces cisplatin accumulation and nephrotoxicity in Mrp2-null mice.

Wen X, Buckley B, McCandlish E, Goedken MJ, Syed S, Pelis R, Manautou JE, Aleksunes LM.

Am J Pathol. 2014 May;184(5):1299-308. doi: 10.1016/j.ajpath.2014.01.025. Epub 2014 Mar 15.

Supplemental Content

Loading ...
Support Center