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Items: 1 to 20 of 50

1.

Microfluidic platform for characterizing TCR-pMHC interactions.

Stockslager MA, Bagnall JS, Hecht VC, Hu K, Aranda-Michel E, Payer K, Kimmerling RJ, Manalis SR.

Biomicrofluidics. 2017 Nov 14;11(6):064103. doi: 10.1063/1.5002116. eCollection 2017 Nov.

PMID:
29204244
2.

Determining therapeutic susceptibility in multiple myeloma by single-cell mass accumulation.

Cetin AE, Stevens MM, Calistri NL, Fulciniti M, Olcum S, Kimmerling RJ, Munshi NC, Manalis SR.

Nat Commun. 2017 Nov 20;8(1):1613. doi: 10.1038/s41467-017-01593-2.

3.

Direct single-cell biomass estimates for marine bacteria via Archimedes' principle.

Cermak N, Becker JW, Knudsen SM, Chisholm SW, Manalis SR, Polz MF.

ISME J. 2017 Mar;11(3):825-828. doi: 10.1038/ismej.2016.161. Epub 2016 Dec 6.

PMID:
27922599
4.

Drug sensitivity of single cancer cells is predicted by changes in mass accumulation rate.

Stevens MM, Maire CL, Chou N, Murakami MA, Knoff DS, Kikuchi Y, Kimmerling RJ, Liu H, Haidar S, Calistri NL, Cermak N, Olcum S, Cordero NA, Idbaih A, Wen PY, Weinstock DM, Ligon KL, Manalis SR.

Nat Biotechnol. 2016 Nov;34(11):1161-1167. doi: 10.1038/nbt.3697. Epub 2016 Oct 10.

5.

High-throughput measurement of single-cell growth rates using serial microfluidic mass sensor arrays.

Cermak N, Olcum S, Delgado FF, Wasserman SC, Payer KR, A Murakami M, Knudsen SM, Kimmerling RJ, Stevens MM, Kikuchi Y, Sandikci A, Ogawa M, Agache V, Baléras F, Weinstock DM, Manalis SR.

Nat Biotechnol. 2016 Oct;34(10):1052-1059. doi: 10.1038/nbt.3666. Epub 2016 Sep 5.

6.

Deformability-based cell selection with downstream immunofluorescence analysis.

Shaw Bagnall J, Byun S, Miyamoto DT, Kang JH, Maheswaran S, Stott SL, Toner M, Manalis SR.

Integr Biol (Camb). 2016 May 16;8(5):654-64. doi: 10.1039/c5ib00284b. Epub 2016 Mar 21.

7.

Amino Acids Rather than Glucose Account for the Majority of Cell Mass in Proliferating Mammalian Cells.

Hosios AM, Hecht VC, Danai LV, Johnson MO, Rathmell JC, Steinhauser ML, Manalis SR, Vander Heiden MG.

Dev Cell. 2016 Mar 7;36(5):540-9. doi: 10.1016/j.devcel.2016.02.012.

8.

Biophysical changes reduce energetic demand in growth factor-deprived lymphocytes.

Hecht VC, Sullivan LB, Kimmerling RJ, Kim DH, Hosios AM, Stockslager MA, Stevens MM, Kang JH, Wirtz D, Vander Heiden MG, Manalis SR.

J Cell Biol. 2016 Feb 15;212(4):439-47. doi: 10.1083/jcb.201506118.

9.

A microfluidic platform enabling single-cell RNA-seq of multigenerational lineages.

Kimmerling RJ, Lee Szeto G, Li JW, Genshaft AS, Kazer SW, Payer KR, de Riba Borrajo J, Blainey PC, Irvine DJ, Shalek AK, Manalis SR.

Nat Commun. 2016 Jan 6;7:10220. doi: 10.1038/ncomms10220.

10.

Deformability of Tumor Cells versus Blood Cells.

Shaw Bagnall J, Byun S, Begum S, Miyamoto DT, Hecht VC, Maheswaran S, Stott SL, Toner M, Hynes RO, Manalis SR.

Sci Rep. 2015 Dec 18;5:18542. doi: 10.1038/srep18542.

11.

Cooperative nutrient accumulation sustains growth of mammalian cells.

Son S, Stevens MM, Chao HX, Thoreen C, Hosios AM, Schweitzer LD, Weng Y, Wood K, Sabatini D, Vander Heiden MG, Manalis S.

Sci Rep. 2015 Dec 1;5:17401. doi: 10.1038/srep17401.

12.

Resonant microchannel volume and mass measurements show that suspended cells swell during mitosis.

Son S, Kang JH, Oh S, Kirschner MW, Mitchison TJ, Manalis S.

J Cell Biol. 2015 Nov 23;211(4):757-63. doi: 10.1083/jcb.201505058.

13.

Characterizing Cellular Biophysical Responses to Stress by Relating Density, Deformability, and Size.

Byun S, Hecht VC, Manalis SR.

Biophys J. 2015 Oct 20;109(8):1565-73. doi: 10.1016/j.bpj.2015.08.038.

14.

Water and Small-Molecule Permeation of Dormant Bacillus subtilis Spores.

Knudsen SM, Cermak N, Delgado FF, Setlow B, Setlow P, Manalis SR.

J Bacteriol. 2015 Oct 19;198(1):168-77. doi: 10.1128/JB.00435-15.

15.

High-speed multiple-mode mass-sensing resolves dynamic nanoscale mass distributions.

Olcum S, Cermak N, Wasserman SC, Manalis SR.

Nat Commun. 2015 May 12;6:7070. doi: 10.1038/ncomms8070.

16.

Pyruvate kinase isoform expression alters nucleotide synthesis to impact cell proliferation.

Lunt SY, Muralidhar V, Hosios AM, Israelsen WJ, Gui DY, Newhouse L, Ogrodzinski M, Hecht V, Xu K, Acevedo PN, Hollern DP, Bellinger G, Dayton TL, Christen S, Elia I, Dinh AT, Stephanopoulos G, Manalis SR, Yaffe MB, Andrechek ER, Fendt SM, Vander Heiden MG.

Mol Cell. 2015 Jan 8;57(1):95-107. doi: 10.1016/j.molcel.2014.10.027. Epub 2014 Dec 4.

17.

In vivo volume and hemoglobin dynamics of human red blood cells.

Malka R, Delgado FF, Manalis SR, Higgins JM.

PLoS Comput Biol. 2014 Oct 9;10(10):e1003839. doi: 10.1371/journal.pcbi.1003839. eCollection 2014 Oct.

18.

Weighing nanoparticles in solution at the attogram scale.

Olcum S, Cermak N, Wasserman SC, Christine KS, Atsumi H, Payer KR, Shen W, Lee J, Belcher AM, Bhatia SN, Manalis SR.

Proc Natl Acad Sci U S A. 2014 Jan 28;111(4):1310-5. doi: 10.1073/pnas.1318602111. Epub 2014 Jan 13.

19.

Measuring single cell mass, volume, and density with dual suspended microchannel resonators.

Bryan AK, Hecht VC, Shen W, Payer K, Grover WH, Manalis SR.

Lab Chip. 2014 Feb 7;14(3):569-576. doi: 10.1039/c3lc51022k.

20.

Intracellular water exchange for measuring the dry mass, water mass and changes in chemical composition of living cells.

Feijó Delgado F, Cermak N, Hecht VC, Son S, Li Y, Knudsen SM, Olcum S, Higgins JM, Chen J, Grover WH, Manalis SR.

PLoS One. 2013 Jul 2;8(7):e67590. doi: 10.1371/journal.pone.0067590. Print 2013. Erratum in: PLoS One. 2013;8(9). doi:10.1371/annotation/c3a3219b-935b-42ed-b3a7-bbbc36dc1dfe.

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