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Cancer-associated pathways and biomarkers of venous thrombosis.

Hisada Y, Mackman N.

Blood. 2017 Sep 28;130(13):1499-1506. doi: 10.1182/blood-2017-03-743211. Epub 2017 Aug 14. Review.


Thrombin promotes diet-induced obesity through fibrin-driven inflammation.

Kopec AK, Abrahams SR, Thornton S, Palumbo JS, Mullins ES, Divanovic S, Weiler H, Owens AP 3rd, Mackman N, Goss A, van Ryn J, Luyendyk JP, Flick MJ.

J Clin Invest. 2017 Aug 1;127(8):3152-3166. doi: 10.1172/JCI92744. Epub 2017 Jul 24.


A monocyte-TNF-endothelial activation axis in sickle transgenic mice: Therapeutic benefit from TNF blockade.

Solovey A, Somani A, Belcher JD, Milbauer L, Vincent L, Pawlinski R, Nath KA, Kelm RJ Jr, Mackman N, O'Sullivan MG, Gupta K, Vercellotti GM, Hebbel RP.

Am J Hematol. 2017 Nov;92(11):1119-1130. doi: 10.1002/ajh.24856. Epub 2017 Jul 29.


Enzymatic lipid oxidation by eosinophils propagates coagulation, hemostasis, and thrombotic disease.

Uderhardt S, Ackermann JA, Fillep T, Hammond VJ, Willeit J, Santer P, Mayr M, Biburger M, Miller M, Zellner KR, Stark K, Zarbock A, Rossaint J, Schubert I, Mielenz D, Dietel B, Raaz-Schrauder D, Ay C, Gremmel T, Thaler J, Heim C, Herrmann M, Collins PW, Schabbauer G, Mackman N, Voehringer D, Nadler JL, Lee JJ, Massberg S, Rauh M, Kiechl S, Schett G, O'Donnell VB, Krönke G.

J Exp Med. 2017 Jul 3;214(7):2121-2138. doi: 10.1084/jem.20161070. Epub 2017 May 31.


Evaluation of venous thrombosis and tissue factor in epithelial ovarian cancer.

Cohen JG, Prendergast E, Geddings JE, Walts AE, Agadjanian H, Hisada Y, Karlan BY, Mackman N, Walsh CS.

Gynecol Oncol. 2017 Jul;146(1):146-152. doi: 10.1016/j.ygyno.2017.04.021. Epub 2017 May 10.


Methodological Guidelines to Study Extracellular Vesicles.

Coumans FAW, Brisson AR, Buzas EI, Dignat-George F, Drees EEE, El-Andaloussi S, Emanueli C, Gasecka A, Hendrix A, Hill AF, Lacroix R, Lee Y, van Leeuwen TG, Mackman N, Mäger I, Nolan JP, van der Pol E, Pegtel DM, Sahoo S, Siljander PRM, Sturk G, de Wever O, Nieuwland R.

Circ Res. 2017 May 12;120(10):1632-1648. doi: 10.1161/CIRCRESAHA.117.309417. Review.


Detection of tissue factor-positive extracellular vesicles by laser scanning confocal microscopy.

Hisada Y, Auriemma AC, Alexander W, Ay C, Mackman N.

Thromb Res. 2017 Feb;150:65-72. doi: 10.1016/j.thromres.2016.12.021. Epub 2016 Dec 23.


Tissue Factor: Catch Me If You Can!

Ay C, Mackman N.

J Clin Oncol. 2017 Apr 1;35(10):1128-1130. doi: 10.1200/JCO.2016.70.6788. Epub 2016 Dec 28. No abstract available.


Anticoagulation increases alveolar hemorrhage in mice infected with influenza A.

Tatsumi K, Antoniak S, Subramaniam S, Gondouin B, Neidich SD, Beck MA, Mickelson J, Monroe DM 3rd, Bastarache JA, Mackman N.

Physiol Rep. 2016 Dec;4(24). pii: e13071. doi: 10.14814/phy2.13071.


Erratum to "A combined deficiency of tissue factor and PAR-4 is associated with fatal pulmonary hemorrhage in mice" [Thromb. Res. 146 (2016) 46-50].

Bode MF, Mackman N.

Thromb Res. 2017 Jan;149:95. doi: 10.1016/j.thromres.2016.11.005. Epub 2016 Nov 24. No abstract available.


Protease-Activated Receptor 1 Contributes to Angiotensin II-Induced Cardiovascular Remodeling and Inflammation.

Antoniak S, Cardenas JC, Buczek LJ, Church FC, Mackman N, Pawlinski R.

Cardiology. 2017;136(4):258-268. doi: 10.1159/000452269. Epub 2016 Nov 24.


Protease-Activated Receptor 1 Enhances Poly I:C Induction of the Antiviral Response in Macrophages and Mice.

Antoniak S, Tatsumi K, Bode M, Vanja S, Williams JC, Mackman N.

J Innate Immun. 2017;9(2):181-192. doi: 10.1159/000450853. Epub 2016 Nov 8.


Letter to Editor response: Endothelial cell tissue factor and coagulation.

Antoniak S, Mackman N.

Trends Cardiovasc Med. 2017 Feb;27(2):157. doi: 10.1016/j.tcm.2016.09.012. Epub 2016 Oct 5. No abstract available.


Corrigendum to "Measurement of microparticle tissue factor activity in clinical samples: A summary of two tissue factor-dependent FXa generation assays" [Thromb. Res. 139 (2016) 90-97].

Hisada Y, Alexander W, Kasthuri R, Voorhees P, Mobarrez F, Taylor A, McNamara C, Wallen H, MarcoWitkowski, Key NS, Rauch U, Mackman N.

Thromb Res. 2016 Nov;147:63. doi: 10.1016/j.thromres.2016.09.009. Epub 2016 Sep 24. No abstract available.


Corrigendum to 'Microvesicle-associated tissue factor procoagulant activity for the preoperative diagnosis of ovarian cancer", [Thromb. Res. 141 (2016) 39-48].

Claussen C, Rausch AV, Lezius S, Amirkhosravi A, Davila M, Francis JL, Hisada YM, Mackman N, Bokemeyer C, Schmalfeldt B, Mahner S, Langer F.

Thromb Res. 2016 Oct;146:135. doi: 10.1016/j.thromres.2016.09.008. Epub 2016 Sep 16. No abstract available.


A combined deficiency of tissue factor and PAR-4 is associated with fatal pulmonary hemorrhage in mice.

Bode MF, Mackman N.

Thromb Res. 2016 Oct;146:46-50. doi: 10.1016/j.thromres.2016.08.023. Epub 2016 Aug 22. Erratum in: Thromb Res. 2017 Jan;149:95.


Thrombosis in Cancer: Research Priorities Identified by a National Cancer Institute/National Heart, Lung, and Blood Institute Strategic Working Group.

Key NS, Khorana AA, Mackman N, McCarty OJ, White GC, Francis CW, McCrae KR, Palumbo JS, Raskob GE, Chan AT, Sood AK.

Cancer Res. 2016 Jul 1;76(13):3671-5. doi: 10.1158/0008-5472.CAN-15-3100. Epub 2016 Jun 20.


Protective and detrimental effects of neuroectodermal cell-derived tissue factor in mouse models of stroke.

Wang S, Reeves B, Sparkenbaugh EM, Russell J, Soltys Z, Zhang H, Faber JE, Key NS, Kirchhofer D, Granger DN, Mackman N, Pawlinski R.

JCI Insight. 2016 Jul 21;1(11). pii: e86663.


Complying With the National Institutes of Health Guidelines and Principles for Rigor and Reproducibility: Refutations.

Daugherty A, Hegele RA, Mackman N, Rader DJ, Schmidt AM, Weber C.

Arterioscler Thromb Vasc Biol. 2016 Jul;36(7):1303-4. doi: 10.1161/ATVBAHA.116.307906. No abstract available.


Mouse models of venous thrombosis are not equal.

Mackman N.

Blood. 2016 May 26;127(21):2510-1. doi: 10.1182/blood-2016-03-704270. No abstract available.

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