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Items: 1 to 20 of 169

1.

Type I interferon is required for T helper (Th) 2 induction by dendritic cells.

Webb LM, Lundie RJ, Borger JG, Brown SL, Connor LM, Cartwright AN, Dougall AM, Wilbers RH, Cook PC, Jackson-Jones LH, Phythian-Adams AT, Johansson C, Davis DM, Dewals BG, Ronchese F, MacDonald AS.

EMBO J. 2017 Aug 15;36(16):2404-2418. doi: 10.15252/embj.201695345. Epub 2017 Jul 17.

2.

Different populations of CD11b+ dendritic cells drive Th2 responses in the small intestine and colon.

Mayer JU, Demiri M, Agace WW, MacDonald AS, Svensson-Frej M, Milling SW.

Nat Commun. 2017 Jun 9;8:15820. doi: 10.1038/ncomms15820.

3.

Diminished airway macrophage expression of the Axl receptor tyrosine kinase is associated with defective efferocytosis in asthma.

Grabiec AM, Denny N, Doherty JA, Happonen KE, Hankinson J, Connolly E, Fife ME, Fujimori T, Fujino N, Goenka A, Holden S, Tavernier G, Shah R, Cook PC, MacDonald AS, Niven RM, Dahlbäck B, Fowler SJ, Simpson A, Hussell T.

J Allergy Clin Immunol. 2017 Apr 12. pii: S0091-6749(17)30585-7. doi: 10.1016/j.jaci.2017.03.024. [Epub ahead of print] No abstract available.

4.

Enteric helminth-induced type I interferon signaling protects against pulmonary virus infection through interaction with the microbiota.

McFarlane AJ, McSorley HJ, Davidson DJ, Fitch PM, Errington C, Mackenzie KJ, Gollwitzer ES, Johnston CJ, MacDonald AS, Edwards MR, Harris NL, Marsland BJ, Maizels RM, Schwarze J.

J Allergy Clin Immunol. 2017 Feb 11. pii: S0091-6749(17)30229-4. doi: 10.1016/j.jaci.2017.01.016. [Epub ahead of print]

PMID:
28196762
5.

Particles from the Echinococcus granulosus laminated layer inhibit IL-4 and growth factor-driven Akt phosphorylation and proliferative responses in macrophages.

Seoane PI, Rückerl D, Casaravilla C, Barrios AA, Pittini Á, MacDonald AS, Allen JE, Díaz A.

Sci Rep. 2016 Dec 14;6:39204. doi: 10.1038/srep39204.

6.

IL-33 delivery induces serous cavity macrophage proliferation independent of interleukin-4 receptor alpha.

Jackson-Jones LH, Rückerl D, Svedberg F, Duncan S, Maizels RM, Sutherland TE, Jenkins SJ, McSorley HJ, Bénézech C, MacDonald AS, Allen JE.

Eur J Immunol. 2016 Oct;46(10):2311-2321. doi: 10.1002/eji.201646442.

7.

Tumor progression locus 2 reduces severe allergic airway inflammation by inhibiting Ccl24 production in dendritic cells.

Kannan Y, Li Y, Coomes SM, Okoye IS, Pelly VS, Sriskantharajah S, Gückel E, Webb L, Czieso S, Nikolov N, MacDonald AS, Ley SC, Wilson MS.

J Allergy Clin Immunol. 2017 Feb;139(2):655-666.e7. doi: 10.1016/j.jaci.2016.05.031. Epub 2016 Jul 5.

8.

Dendritic cells in lung immunopathology.

Cook PC, MacDonald AS.

Semin Immunopathol. 2016 Jul;38(4):449-60. doi: 10.1007/s00281-016-0571-3. Epub 2016 Jun 2. Review.

9.

IL-4-producing ILC2s are required for the differentiation of TH2 cells following Heligmosomoides polygyrus infection.

Pelly VS, Kannan Y, Coomes SM, Entwistle LJ, Rückerl D, Seddon B, MacDonald AS, McKenzie A, Wilson MS.

Mucosal Immunol. 2016 Nov;9(6):1407-1417. doi: 10.1038/mi.2016.4. Epub 2016 Feb 17.

10.

A comparison of health expectancies over two decades in England: results of the Cognitive Function and Ageing Study I and II.

Jagger C, Matthews FE, Wohland P, Fouweather T, Stephan BC, Robinson L, Arthur A, Brayne C; Medical Research Council Cognitive Function and Ageing Collaboration.

Lancet. 2016 Feb 20;387(10020):779-86. doi: 10.1016/S0140-6736(15)00947-2. Epub 2015 Dec 9.

11.

Integrin α4β1 controls G9a activity that regulates epigenetic changes and nuclear properties required for lymphocyte migration.

Zhang X, Cook PC, Zindy E, Williams CJ, Jowitt TA, Streuli CH, MacDonald AS, Redondo-Muñoz J.

Nucleic Acids Res. 2016 Apr 20;44(7):3031-44. doi: 10.1093/nar/gkv1348. Epub 2015 Dec 10.

12.

A central role for hepatic conventional dendritic cells in supporting Th2 responses during helminth infection.

Lundie RJ, Webb LM, Marley AK, Phythian-Adams AT, Cook PC, Jackson-Jones LH, Brown S, Maizels RM, Boon L, O'Keeffe M, MacDonald AS.

Immunol Cell Biol. 2016 Apr;94(4):400-10. doi: 10.1038/icb.2015.114. Epub 2015 Dec 11.

13.

1,25-Dihydroxyvitamin D3-Conditioned CD11c+ Dendritic Cells are Effective Initiators of CNS Autoimmune Disease.

Besusso D, Saul L, Leech MD, O'Connor RA, MacDonald AS, Anderton SM, Mellanby RJ.

Front Immunol. 2015 Nov 18;6:575. doi: 10.3389/fimmu.2015.00575. eCollection 2015.

14.

Schistosoma mansoni Larvae Do Not Expand or Activate Foxp3+ Regulatory T Cells during Their Migratory Phase.

Redpath SA, van der Werf N, MacDonald AS, Maizels RM, Taylor MD.

Infect Immun. 2015 Oct;83(10):3881-9. doi: 10.1128/IAI.00408-15. Epub 2015 Jul 20.

15.

A dominant role for the methyl-CpG-binding protein Mbd2 in controlling Th2 induction by dendritic cells.

Cook PC, Owen H, Deaton AM, Borger JG, Brown SL, Clouaire T, Jones GR, Jones LH, Lundie RJ, Marley AK, Morrison VL, Phythian-Adams AT, Wachter E, Webb LM, Sutherland TE, Thomas GD, Grainger JR, Selfridge J, McKenzie AN, Allen JE, Fagerholm SC, Maizels RM, Ivens AC, Bird A, MacDonald AS.

Nat Commun. 2015 Apr 24;6:6920. doi: 10.1038/ncomms7920.

16.

Modulation of dendritic cell alternative activation and function by the vitamin A metabolite retinoic acid.

Jones LH, Cook PC, Ivens AC, Thomas GD, Phythian-Adams AT, Allen JE, MacDonald AS.

Int Immunol. 2015 Nov;27(11):589-96. doi: 10.1093/intimm/dxv020. Epub 2015 Apr 20.

17.

The adult murine heart has a sparse, phagocytically active macrophage population that expands through monocyte recruitment and adopts an 'M2' phenotype in response to Th2 immunologic challenge.

Mylonas KJ, Jenkins SJ, Castellan RF, Ruckerl D, McGregor K, Phythian-Adams AT, Hewitson JP, Campbell SM, MacDonald AS, Allen JE, Gray GA.

Immunobiology. 2015 Jul;220(7):924-33. doi: 10.1016/j.imbio.2015.01.013. Epub 2015 Feb 7.

18.

The Axl receptor tyrosine kinase is a discriminator of macrophage function in the inflamed lung.

Fujimori T, Grabiec AM, Kaur M, Bell TJ, Fujino N, Cook PC, Svedberg FR, MacDonald AS, Maciewicz RA, Singh D, Hussell T.

Mucosal Immunol. 2015 Sep;8(5):1021-1030. doi: 10.1038/mi.2014.129. Epub 2015 Jan 21.

19.

Loss of beta2-integrin-mediated cytoskeletal linkage reprogrammes dendritic cells to a mature migratory phenotype.

Morrison VL, James MJ, Grzes K, Cook P, Glass DG, Savinko T, Lek HS, Gawden-Bone C, Watts C, Millington OR, MacDonald AS, Fagerholm SC.

Nat Commun. 2014 Oct 28;5:5359. doi: 10.1038/ncomms6359.

20.

MyD88 signaling inhibits protective immunity to the gastrointestinal helminth parasite Heligmosomoides polygyrus.

Reynolds LA, Harcus Y, Smith KA, Webb LM, Hewitson JP, Ross EA, Brown S, Uematsu S, Akira S, Gray D, Gray M, MacDonald AS, Cunningham AF, Maizels RM.

J Immunol. 2014 Sep 15;193(6):2984-93. doi: 10.4049/jimmunol.1401056. Epub 2014 Aug 11.

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