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Items: 13

1.

Sharing and community curation of mass spectrometry data with Global Natural Products Social Molecular Networking.

Wang M, Carver JJ, Phelan VV, Sanchez LM, Garg N, Peng Y, Nguyen DD, Watrous J, Kapono CA, Luzzatto-Knaan T, Porto C, Bouslimani A, Melnik AV, Meehan MJ, Liu WT, Crüsemann M, Boudreau PD, Esquenazi E, Sandoval-Calderón M, Kersten RD, Pace LA, Quinn RA, Duncan KR, Hsu CC, Floros DJ, Gavilan RG, Kleigrewe K, Northen T, Dutton RJ, Parrot D, Carlson EE, Aigle B, Michelsen CF, Jelsbak L, Sohlenkamp C, Pevzner P, Edlund A, McLean J, Piel J, Murphy BT, Gerwick L, Liaw CC, Yang YL, Humpf HU, Maansson M, Keyzers RA, Sims AC, Johnson AR, Sidebottom AM, Sedio BE, Klitgaard A, Larson CB, P CAB, Torres-Mendoza D, Gonzalez DJ, Silva DB, Marques LM, Demarque DP, Pociute E, O'Neill EC, Briand E, Helfrich EJN, Granatosky EA, Glukhov E, Ryffel F, Houson H, Mohimani H, Kharbush JJ, Zeng Y, Vorholt JA, Kurita KL, Charusanti P, McPhail KL, Nielsen KF, Vuong L, Elfeki M, Traxler MF, Engene N, Koyama N, Vining OB, Baric R, Silva RR, Mascuch SJ, Tomasi S, Jenkins S, Macherla V, Hoffman T, Agarwal V, Williams PG, Dai J, Neupane R, Gurr J, Rodríguez AMC, Lamsa A, Zhang C, Dorrestein K, Duggan BM, Almaliti J, Allard PM, Phapale P, Nothias LF, Alexandrov T, Litaudon M, Wolfender JL, Kyle JE, Metz TO, Peryea T, Nguyen DT, VanLeer D, Shinn P, Jadhav A, Müller R, Waters KM, Shi W, Liu X, Zhang L, Knight R, Jensen PR, Palsson BO, Pogliano K, Linington RG, Gutiérrez M, Lopes NP, Gerwick WH, Moore BS, Dorrestein PC, Bandeira N.

Nat Biotechnol. 2016 Aug 9;34(8):828-837. doi: 10.1038/nbt.3597.

2.

Specific and prolonged proteasome inhibition dictates apoptosis induction by marizomib and its analogs.

Miller CP, Manton CA, Hale R, Debose L, Macherla VR, Potts BC, Palladino MA, Chandra J.

Chem Biol Interact. 2011 Oct 15;194(1):58-68. doi: 10.1016/j.cbi.2011.08.005. Epub 2011 Aug 16.

3.

Proteasome regulator marizomib (NPI-0052) exhibits prolonged inhibition, attenuated efflux, and greater cytotoxicity than its reversible analogs.

Obaidat A, Weiss J, Wahlgren B, Manam RR, Macherla VR, McArthur K, Chao TH, Palladino MA, Lloyd GK, Potts BC, Enna SJ, Neuteboom ST, Hagenbuch B.

J Pharmacol Exp Ther. 2011 May;337(2):479-86. doi: 10.1124/jpet.110.177824. Epub 2011 Feb 8.

4.
5.

Snapshots of the fluorosalinosporamide/20S complex offer mechanistic insights for fine tuning proteasome inhibition.

Groll M, McArthur KA, Macherla VR, Manam RR, Potts BC.

J Med Chem. 2009 Sep 10;52(17):5420-8. doi: 10.1021/jm900559x.

PMID:
19678642
6.

Antiprotealide is a natural product.

Manam RR, Macherla VR, Tsueng G, Dring CW, Weiss J, Neuteboom ST, Lam KS, Potts BC.

J Nat Prod. 2009 Feb 27;72(2):295-7. doi: 10.1021/np800578e.

PMID:
19133779
7.

Leaving groups prolong the duration of 20S proteasome inhibition and enhance the potency of salinosporamides.

Manam RR, McArthur KA, Chao TH, Weiss J, Ali JA, Palombella VJ, Groll M, Lloyd GK, Palladino MA, Neuteboom ST, Macherla VR, Potts BC.

J Med Chem. 2008 Nov 13;51(21):6711-24. doi: 10.1021/jm800548b. Epub 2008 Oct 22.

PMID:
18939815
8.

Seawater requirement for the production of lipoxazolidinones by marine actinomycete strain NPS8920.

Sunga MJ, Teisan S, Tsueng G, Macherla VR, Lam KS.

J Ind Microbiol Biotechnol. 2008 Jul;35(7):761-5. doi: 10.1007/s10295-008-0344-7. Epub 2008 Apr 4.

PMID:
18389298
9.

Lipoxazolidinones A, B, and C: antibacterial 4-oxazolidinones from a marine actinomycete isolated from a Guam marine sediment.

Macherla VR, Liu J, Sunga M, White DJ, Grodberg J, Teisan S, Lam KS, Potts BC.

J Nat Prod. 2007 Sep;70(9):1454-7. Epub 2007 Sep 11.

PMID:
17845000
10.

Enantioselective total synthesis of (-)-Salinosporamide A (NPI-0052).

Ling T, Macherla VR, Manam RR, McArthur KA, Potts BC.

Org Lett. 2007 Jun 7;9(12):2289-92. Epub 2007 May 12.

PMID:
17497868
11.

Glaciapyrroles A, B, and C, pyrrolosesquiterpenes from a Streptomyces sp. isolated from an Alaskan marine sediment.

Macherla VR, Liu J, Bellows C, Teisan S, Nicholson B, Lam KS, Potts BC.

J Nat Prod. 2005 May;68(5):780-3.

PMID:
15921430
12.

Structure-activity relationship studies of salinosporamide A (NPI-0052), a novel marine derived proteasome inhibitor.

Macherla VR, Mitchell SS, Manam RR, Reed KA, Chao TH, Nicholson B, Deyanat-Yazdi G, Mai B, Jensen PR, Fenical WF, Neuteboom ST, Lam KS, Palladino MA, Potts BC.

J Med Chem. 2005 Jun 2;48(11):3684-7.

PMID:
15916417
13.

The evolution of crescentic nephritis and alveolar haemorrhage following induction of autoimmunity to glomerular basement membrane in an experimental model of Goodpasture's disease.

Reynolds J, Moss J, Duda MA, Smith J, Karkar AM, Macherla V, Shore I, Evans DJ, Woodrow DF, Pusey CD.

J Pathol. 2003 May;200(1):118-29.

PMID:
12692850

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