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Items: 1 to 20 of 53


Progress in understanding and overcoming biomass recalcitrance: a BioEnergy Science Center (BESC) perspective.

Gilna P, Lynd LR, Mohnen D, Davis MF, Davison BH.

Biotechnol Biofuels. 2017 Nov 30;10:285. doi: 10.1186/s13068-017-0971-1. eCollection 2017.


Deletion of the hfsB gene increases ethanol production in Thermoanaerobacterium saccharolyticum and several other thermophilic anaerobic bacteria.

Eminoğlu A, Murphy SJ, Maloney M, Lanahan A, Giannone RJ, Hettich RL, Tripathi SA, Beldüz AO, Lynd LR, Olson DG.

Biotechnol Biofuels. 2017 Nov 30;10:282. doi: 10.1186/s13068-017-0968-9. eCollection 2017.


Metabolome analysis reveals a role for glyceraldehyde 3-phosphate dehydrogenase in the inhibition of C. thermocellum by ethanol.

Tian L, Perot SJ, Stevenson D, Jacobson T, Lanahan AA, Amador-Noguez D, Olson DG, Lynd LR.

Biotechnol Biofuels. 2017 Nov 30;10:276. doi: 10.1186/s13068-017-0961-3. eCollection 2017.


Expression of adhA from different organisms in Clostridium thermocellum.

Zheng T, Cui J, Bae HR, Lynd LR, Olson DG.

Biotechnol Biofuels. 2017 Nov 30;10:251. doi: 10.1186/s13068-017-0940-8. eCollection 2017.


Enhanced ethanol formation by Clostridium thermocellum via pyruvate decarboxylase.

Tian L, Perot SJ, Hon S, Zhou J, Liang X, Bouvier JT, Guss AM, Olson DG, Lynd LR.

Microb Cell Fact. 2017 Oct 4;16(1):171. doi: 10.1186/s12934-017-0783-9.


Development of a core Clostridium thermocellum kinetic metabolic model consistent with multiple genetic perturbations.

Dash S, Khodayari A, Zhou J, Holwerda EK, Olson DG, Lynd LR, Maranas CD.

Biotechnol Biofuels. 2017 May 2;10:108. doi: 10.1186/s13068-017-0792-2. eCollection 2017.


Both adhE and a separate NADPH-dependent alcohol dehydrogenase (adhA) are necessary for high ethanol production in Thermoanaerobacterium saccharolyticum.

Zheng T, Olson DG, Murphy SJ, Shao X, Tian L, Lynd LR.

J Bacteriol. 2016 Nov 14. pii: JB.00542-16. [Epub ahead of print]


Ferredoxin:NAD+ Oxidoreductase of Thermoanaerobacterium saccharolyticum and Its Role in Ethanol Formation.

Tian L, Lo J, Shao X, Zheng T, Olson DG, Lynd LR.

Appl Environ Microbiol. 2016 Nov 21;82(24):7134-7141. Print 2016 Dec 15.


Strain and bioprocess improvement of a thermophilic anaerobe for the production of ethanol from wood.

Herring CD, Kenealy WR, Joe Shaw A, Covalla SF, Olson DG, Zhang J, Ryan Sillers W, Tsakraklides V, Bardsley JS, Rogers SR, Thorne PG, Johnson JP, Foster A, Shikhare ID, Klingeman DM, Brown SD, Davison BH, Lynd LR, Hogsett DA.

Biotechnol Biofuels. 2016 Jun 16;9:125. doi: 10.1186/s13068-016-0536-8. eCollection 2016.


Simultaneous achievement of high ethanol yield and titer in Clostridium thermocellum.

Tian L, Papanek B, Olson DG, Rydzak T, Holwerda EK, Zheng T, Zhou J, Maloney M, Jiang N, Giannone RJ, Hettich RL, Guss AM, Lynd LR.

Biotechnol Biofuels. 2016 Jun 2;9:116. doi: 10.1186/s13068-016-0528-8. eCollection 2016.


A markerless gene deletion and integration system for Thermoanaerobacter ethanolicus.

Shao X, Zhou J, Olson DG, Lynd LR.

Biotechnol Biofuels. 2016 May 4;9:100. doi: 10.1186/s13068-016-0514-1. eCollection 2016.


Development of a plasmid-based expression system in Clostridium thermocellum and its use to screen heterologous expression of bifunctional alcohol dehydrogenases (adhEs).

Hon S, Lanahan AA, Tian L, Giannone RJ, Hettich RL, Olson DG, Lynd LR.

Metab Eng Commun. 2016 Apr 22;3:120-129. doi: 10.1016/j.meteno.2016.04.001. eCollection 2016 Dec.


Dramatic performance of Clostridium thermocellum explained by its wide range of cellulase modalities.

Xu Q, Resch MG, Podkaminer K, Yang S, Baker JO, Donohoe BS, Wilson C, Klingeman DM, Olson DG, Decker SR, Giannone RJ, Hettich RL, Brown SD, Lynd LR, Bayer EA, Himmel ME, Bomble YJ.

Sci Adv. 2016 Feb 5;2(2):e1501254. doi: 10.1126/sciadv.1501254. eCollection 2016 Feb.


Promiscuous plasmid replication in thermophiles: Use of a novel hyperthermophilic replicon for genetic manipulation of Clostridium thermocellum at its optimum growth temperature.

Groom J, Chung D, Olson DG, Lynd LR, Guss AM, Westpheling J.

Metab Eng Commun. 2016 Jan 29;3:30-38. doi: 10.1016/j.meteno.2016.01.004. eCollection 2016 Dec.


Biological lignocellulose solubilization: comparative evaluation of biocatalysts and enhancement via cotreatment.

Paye JM, Guseva A, Hammer SK, Gjersing E, Davis MF, Davison BH, Olstad J, Donohoe BS, Nguyen TY, Wyman CE, Pattathil S, Hahn MG, Lynd LR.

Biotechnol Biofuels. 2016 Jan 12;9:8. doi: 10.1186/s13068-015-0412-y. eCollection 2016.


Correction for Lo et al., Deletion of nfnAB in Thermoanaerobacterium saccharolyticum and Its Effect on Metabolism.

Lo J, Zheng T, Olson DG, Ruppertsberger N, Tripathi SA, Tian L, Guss AM, Lynd LR.

J Bacteriol. 2015 Oct;197(20):3367. doi: 10.1128/JB.00688-15. No abstract available.


Physiological roles of pyruvate ferredoxin oxidoreductase and pyruvate formate-lyase in Thermoanaerobacterium saccharolyticum JW/SL-YS485.

Zhou J, Olson DG, Lanahan AA, Tian L, Murphy SJ, Lo J, Lynd LR.

Biotechnol Biofuels. 2015 Sep 15;8:138. doi: 10.1186/s13068-015-0304-1. eCollection 2015.


Draft Genome Sequence of the Cellulolytic and Xylanolytic Thermophile Clostridium clariflavum Strain 4-2a.

Rooney EA, Rowe KT, Guseva A, Huntemann M, Han JK, Chen A, Kyrpides NC, Mavromatis K, Markowitz VM, Palaniappan K, Ivanova N, Pati A, Liolios K, Nordberg HP, Cantor MN, Hua SX, Shapiro N, Woyke T, Lynd LR, Izquierdo JA.

Genome Announc. 2015 Jul 23;3(4). pii: e00797-15. doi: 10.1128/genomeA.00797-15.


Deletion of nfnAB in Thermoanaerobacterium saccharolyticum and Its Effect on Metabolism.

Lo J, Zheng T, Olson DG, Ruppertsberger N, Tripathi SA, Tian L, Guss AM, Lynd LR.

J Bacteriol. 2015 Sep;197(18):2920-9. doi: 10.1128/JB.00347-15. Epub 2015 Jun 29. Erratum in: J Bacteriol. 2015 Oct;197(20):3367. Tian, Liang [added].


Genome-scale resources for Thermoanaerobacterium saccharolyticum.

Currie DH, Raman B, Gowen CM, Tschaplinski TJ, Land ML, Brown SD, Covalla SF, Klingeman DM, Yang ZK, Engle NL, Johnson CM, Rodriguez M, Shaw AJ, Kenealy WR, Lynd LR, Fong SS, Mielenz JR, Davison BH, Hogsett DA, Herring CD.

BMC Syst Biol. 2015 Jun 26;9:30. doi: 10.1186/s12918-015-0159-x.

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