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Items: 1 to 20 of 106


Progress in understanding and overcoming biomass recalcitrance: a BioEnergy Science Center (BESC) perspective.

Gilna P, Lynd LR, Mohnen D, Davis MF, Davison BH.

Biotechnol Biofuels. 2017 Nov 30;10:285. doi: 10.1186/s13068-017-0971-1. eCollection 2017.


Deletion of the hfsB gene increases ethanol production in Thermoanaerobacterium saccharolyticum and several other thermophilic anaerobic bacteria.

Eminoğlu A, Murphy SJ, Maloney M, Lanahan A, Giannone RJ, Hettich RL, Tripathi SA, Beldüz AO, Lynd LR, Olson DG.

Biotechnol Biofuels. 2017 Nov 30;10:282. doi: 10.1186/s13068-017-0968-9. eCollection 2017.


Metabolome analysis reveals a role for glyceraldehyde 3-phosphate dehydrogenase in the inhibition of C. thermocellum by ethanol.

Tian L, Perot SJ, Stevenson D, Jacobson T, Lanahan AA, Amador-Noguez D, Olson DG, Lynd LR.

Biotechnol Biofuels. 2017 Nov 30;10:276. doi: 10.1186/s13068-017-0961-3. eCollection 2017.


Expression of adhA from different organisms in Clostridium thermocellum.

Zheng T, Cui J, Bae HR, Lynd LR, Olson DG.

Biotechnol Biofuels. 2017 Nov 30;10:251. doi: 10.1186/s13068-017-0940-8. eCollection 2017.


Lignocellulose deconstruction in the biosphere.

Bomble YJ, Lin CY, Amore A, Wei H, Holwerda EK, Ciesielski PN, Donohoe BS, Decker SR, Lynd LR, Himmel ME.

Curr Opin Chem Biol. 2017 Dec;41:61-70. doi: 10.1016/j.cbpa.2017.10.013. Epub 2017 Nov 2. Review.


The grand challenge of cellulosic biofuels.

Lynd LR.

Nat Biotechnol. 2017 Oct 11;35(10):912-915. doi: 10.1038/nbt.3976. No abstract available.


Enhanced ethanol formation by Clostridium thermocellum via pyruvate decarboxylase.

Tian L, Perot SJ, Hon S, Zhou J, Liang X, Bouvier JT, Guss AM, Olson DG, Lynd LR.

Microb Cell Fact. 2017 Oct 4;16(1):171. doi: 10.1186/s12934-017-0783-9.


The ethanol pathway from Thermoanaerobacterium saccharolyticum improves ethanol production in Clostridium thermocellum.

Hon S, Olson DG, Holwerda EK, Lanahan AA, Murphy SJL, Maloney MI, Zheng T, Papanek B, Guss AM, Lynd LR.

Metab Eng. 2017 Jul;42:175-184. doi: 10.1016/j.ymben.2017.06.011. Epub 2017 Jun 27.


Cellulosic ethanol: status and innovation.

Lynd LR, Liang X, Biddy MJ, Allee A, Cai H, Foust T, Himmel ME, Laser MS, Wang M, Wyman CE.

Curr Opin Biotechnol. 2017 Jun;45:202-211. doi: 10.1016/j.copbio.2017.03.008. Epub 2017 May 18. Review.


Development of a core Clostridium thermocellum kinetic metabolic model consistent with multiple genetic perturbations.

Dash S, Khodayari A, Zhou J, Holwerda EK, Olson DG, Lynd LR, Maranas CD.

Biotechnol Biofuels. 2017 May 2;10:108. doi: 10.1186/s13068-017-0792-2. eCollection 2017.


Determining the roles of the three alcohol dehydrogenases (AdhA, AdhB and AdhE) in Thermoanaerobacter ethanolicus during ethanol formation.

Zhou J, Shao X, Olson DG, Murphy SJ, Tian L, Lynd LR.

J Ind Microbiol Biotechnol. 2017 May;44(4-5):745-757. doi: 10.1007/s10295-016-1896-6. Epub 2017 Jan 11.


Engineering electron metabolism to increase ethanol production in Clostridium thermocellum.

Lo J, Olson DG, Murphy SJ, Tian L, Hon S, Lanahan A, Guss AM, Lynd LR.

Metab Eng. 2017 Jan;39:71-79. doi: 10.1016/j.ymben.2016.10.018. Epub 2016 Oct 28.


Glycolysis without pyruvate kinase in Clostridium thermocellum.

Olson DG, Hörl M, Fuhrer T, Cui J, Zhou J, Maloney MI, Amador-Noguez D, Tian L, Sauer U, Lynd LR.

Metab Eng. 2017 Jan;39:169-180. doi: 10.1016/j.ymben.2016.11.011. Epub 2016 Dec 1.


Both adhE and a separate NADPH-dependent alcohol dehydrogenase (adhA) are necessary for high ethanol production in Thermoanaerobacterium saccharolyticum.

Zheng T, Olson DG, Murphy SJ, Shao X, Tian L, Lynd LR.

J Bacteriol. 2016 Nov 14. pii: JB.00542-16. [Epub ahead of print]


Ferredoxin:NAD+ Oxidoreductase of Thermoanaerobacterium saccharolyticum and Its Role in Ethanol Formation.

Tian L, Lo J, Shao X, Zheng T, Olson DG, Lynd LR.

Appl Environ Microbiol. 2016 Nov 21;82(24):7134-7141. Print 2016 Dec 15.


Strain and bioprocess improvement of a thermophilic anaerobe for the production of ethanol from wood.

Herring CD, Kenealy WR, Joe Shaw A, Covalla SF, Olson DG, Zhang J, Ryan Sillers W, Tsakraklides V, Bardsley JS, Rogers SR, Thorne PG, Johnson JP, Foster A, Shikhare ID, Klingeman DM, Brown SD, Davison BH, Lynd LR, Hogsett DA.

Biotechnol Biofuels. 2016 Jun 16;9:125. doi: 10.1186/s13068-016-0536-8. eCollection 2016.


Simultaneous achievement of high ethanol yield and titer in Clostridium thermocellum.

Tian L, Papanek B, Olson DG, Rydzak T, Holwerda EK, Zheng T, Zhou J, Maloney M, Jiang N, Giannone RJ, Hettich RL, Guss AM, Lynd LR.

Biotechnol Biofuels. 2016 Jun 2;9:116. doi: 10.1186/s13068-016-0528-8. eCollection 2016.


Nicotinamide cofactor ratios in engineered strains of Clostridium thermocellum and Thermoanaerobacterium saccharolyticum.

Beri D, Olson DG, Holwerda EK, Lynd LR.

FEMS Microbiol Lett. 2016 Jun;363(11). pii: fnw091. doi: 10.1093/femsle/fnw091. Epub 2016 Apr 11.


A markerless gene deletion and integration system for Thermoanaerobacter ethanolicus.

Shao X, Zhou J, Olson DG, Lynd LR.

Biotechnol Biofuels. 2016 May 4;9:100. doi: 10.1186/s13068-016-0514-1. eCollection 2016.


Development of a plasmid-based expression system in Clostridium thermocellum and its use to screen heterologous expression of bifunctional alcohol dehydrogenases (adhEs).

Hon S, Lanahan AA, Tian L, Giannone RJ, Hettich RL, Olson DG, Lynd LR.

Metab Eng Commun. 2016 Apr 22;3:120-129. doi: 10.1016/j.meteno.2016.04.001. eCollection 2016 Dec.

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