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Items: 1 to 20 of 57


APOE ε4-TOMM40 '523 haplotypes and the risk of Alzheimer's disease in older Caucasian and African Americans.

Yu L, Lutz MW, Wilson RS, Burns DK, Roses AD, Saunders AM, Yang J, Gaiteri C, De Jager PL, Barnes LL, Bennett DA.

PLoS One. 2017 Jul 3;12(7):e0180356. doi: 10.1371/journal.pone.0180356. eCollection 2017.


Neuropathologic features of TOMM40 '523 variant on late-life cognitive decline.

Yu L, Lutz MW, Farfel JM, Wilson RS, Burns DK, Saunders AM, De Jager PL, Barnes LL, Schneider JA, Bennett DA.

Alzheimers Dement. 2017 Jun 15. pii: S1552-5260(17)30217-0. doi: 10.1016/j.jalz.2017.05.002. [Epub ahead of print]


Family history and TOMM40 '523 interactive associations with memory in middle-aged and Alzheimer's disease cohorts.

Willette AA, Webb JL, Lutz MW, Bendlin BB, Wennberg AM, Oh JM, Roses A, Koscik RL, Hermann BP, Dowling NM, Asthana S, Johnson SC; Alzheimer's Disease Neuroimaging Initiative.

Alzheimers Dement. 2017 May 10. pii: S1552-5260(17)30148-6. doi: 10.1016/j.jalz.2017.03.009. [Epub ahead of print]


Genetic analysis of α-synuclein 3' untranslated region and its corresponding microRNAs in relation to Parkinson's compared to dementia with Lewy bodies.

Tagliafierro L, Glenn OC, Zamora ME, Beach TG, Woltjer RL, Lutz MW, Chiba-Falek O.

Alzheimers Dement. 2017 Apr 18. pii: S1552-5260(17)30136-X. doi: 10.1016/j.jalz.2017.03.001. [Epub ahead of print]


The Alu neurodegeneration hypothesis: A primate-specific mechanism for neuronal transcription noise, mitochondrial dysfunction, and manifestation of neurodegenerative disease.

Larsen PA, Lutz MW, Hunnicutt KE, Mihovilovic M, Saunders AM, Yoder AD, Roses AD.

Alzheimers Dement. 2017 Jul;13(7):828-838. doi: 10.1016/j.jalz.2017.01.017. Epub 2017 Feb 24.


TOMM40'523 variant and cognitive decline in older persons with APOE ε3/3 genotype.

Yu L, Lutz MW, Wilson RS, Burns DK, Roses AD, Saunders AM, Gaiteri C, De Jager PL, Barnes LL, Bennett DA.

Neurology. 2017 Feb 14;88(7):661-668. doi: 10.1212/WNL.0000000000003614. Epub 2017 Jan 20.


The SSV Evaluation System: A Tool to Prioritize Short Structural Variants for Studies of Possible Regulatory and Causal Variants.

Saul R, Lutz MW, Burns DK, Roses AD, Chiba-Falek O.

Hum Mutat. 2016 Sep;37(9):877-83. doi: 10.1002/humu.23023. Epub 2016 Jun 27.


Blood glucose levels and cortical thinning in cognitively normal, middle-aged adults.

Wennberg AM, Spira AP, Pettigrew C, Soldan A, Zipunnikov V, Rebok GW, Roses AD, Lutz MW, Miller MM, Thambisetty M, Albert MS.

J Neurol Sci. 2016 Jun 15;365:89-95. doi: 10.1016/j.jns.2016.04.017. Epub 2016 Apr 14.


A Genetics-based Biomarker Risk Algorithm for Predicting Risk of Alzheimer's Disease.

Lutz MW, Sundseth SS, Burns DK, Saunders AM, Hayden KM, Burke JR, Welsh-Bohmer KA, Roses AD.

Alzheimers Dement (N Y). 2016 Jan 1;2(1):30-44.


New Genetic Approaches to AD: Lessons from APOE-TOMM40 Phylogenetics.

Lutz MW, Crenshaw D, Welsh-Bohmer KA, Burns DK, Roses AD.

Curr Neurol Neurosci Rep. 2016 May;16(5):48. doi: 10.1007/s11910-016-0643-8. Review.


Novel loci and pathways significantly associated with longevity.

Zeng Y, Nie C, Min J, Liu X, Li M, Chen H, Xu H, Wang M, Ni T, Li Y, Yan H, Zhang JP, Song C, Chi LQ, Wang HM, Dong J, Zheng GY, Lin L, Qian F, Qi Y, Liu X, Cao H, Wang Y, Zhang L, Li Z, Zhou Y, Wang Y, Lu J, Li J, Qi M, Bolund L, Yashin A, Land KC, Gregory S, Yang Z, Gottschalk W, Tao W, Wang J, Wang J, Xu X, Bae H, Nygaard M, Christiansen L, Christensen K, Franceschi C, Lutz MW, Gu J, Tan Q, Perls T, Sebastiani P, Deelen J, Slagboom E, Hauser E, Xu H, Tian XL, Yang H, Vaupel JW.

Sci Rep. 2016 Feb 25;6:21243. doi: 10.1038/srep21243.


Structural variants can be more informative for disease diagnostics, prognostics and translation than current SNP mapping and exon sequencing.

Roses AD, Akkari PA, Chiba-Falek O, Lutz MW, Gottschalk WK, Saunders AM, Saul B, Sundseth S, Burns D.

Expert Opin Drug Metab Toxicol. 2016;12(2):135-47. doi: 10.1517/17425255.2016.1133586. Epub 2016 Feb 2. Review.


Interaction Between the FOXO1A-209 Genotype and Tea Drinking Is Significantly Associated with Reduced Mortality at Advanced Ages.

Zeng Y, Chen H, Ni T, Ruan R, Nie C, Liu X, Feng L, Zhang F, Lu J, Li J, Li Y, Tao W, Gregory SG, Gottschalk W, Lutz MW, Land KC, Yashin A, Tan Q, Yang Z, Bolund L, Ming Q, Yang H, Min J, Willcox DC, Willcox BJ, Gu J, Hauser E, Tian XL, Vaupel JW.

Rejuvenation Res. 2016 Jun;19(3):195-203. doi: 10.1089/rej.2015.1737. Epub 2016 Feb 10.


APOE/TOMM40 genetic loci, white matter hyperintensities, and cerebral microbleeds.

Lyall DM, Muñoz Maniega S, Harris SE, Bastin ME, Murray C, Lutz MW, Saunders AM, Roses AD, Valdés Hernández Mdel C, Royle NA, Starr JM, Porteous DJ, Deary IJ, Wardlaw JM.

Int J Stroke. 2015 Dec;10(8):1297-300. doi: 10.1111/ijs.12615. Epub 2015 Aug 26.


Cardiovascular Imaging for the Primary Prevention of Atherosclerotic Cardiovascular Disease Events.

Weber LA, Cheezum MK, Reese JM, Lane AB, Haley RD, Lutz MW, Villines TC.

Curr Cardiovasc Imaging Rep. 2015;8(9):36. Review.


Correction: Effect of APOE and CD33 on Cognitive Decline.

Hayden KM, Lutz MW, Kuchibhatla M, Germain C, Plassman BL.

PLoS One. 2015 Jul 31;10(7):e0134887. doi: 10.1371/journal.pone.0134887. eCollection 2015. No abstract available.


Effect of APOE and CD33 on Cognitive Decline.

Hayden KM, Lutz MW, Kuchibhatla M, Germain C, Plassman BL.

PLoS One. 2015 Jun 23;10(6):e0130419. doi: 10.1371/journal.pone.0130419. eCollection 2015. Erratum in: PLoS One. 2015;10(7):e0134887.


A cytosine-thymine (CT)-rich haplotype in intron 4 of SNCA confers risk for Lewy body pathology in Alzheimer's disease and affects SNCA expression.

Lutz MW, Saul R, Linnertz C, Glenn OC, Roses AD, Chiba-Falek O.

Alzheimers Dement. 2015 Oct;11(10):1133-43. doi: 10.1016/j.jalz.2015.05.011. Epub 2015 Jun 13.


The Broad Impact of TOM40 on Neurodegenerative Diseases in Aging.

Gottschalk WK, Lutz MW, He YT, Saunders AM, Burns DK, Roses AD, Chiba-Falek O.

J Parkinsons Dis Alzheimers Dis. 2014 Nov;1(1). pii: 12.


African-American TOMM40'523-APOE haplotypes are admixture of West African and Caucasian alleles.

Roses AD, Lutz MW, Saunders AM, Goldgaber D, Saul R, Sundseth SS, Akkari PA, Roses SM, Gottschalk WK, Whitfield KE, Vostrov AA, Hauser MA, Allingham RR, Burns DK, Chiba-Falek O, Welsh-Bohmer KA.

Alzheimers Dement. 2014 Nov;10(6):592-601.e2. doi: 10.1016/j.jalz.2014.06.009. Epub 2014 Sep 26.

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