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Items: 1 to 20 of 360

1.

Targeted next-generation sequencing of endometrial cancer and matched circulating tumor DNA: identification of plasma-based, tumor-associated mutations in early stage patients.

Bolivar AM, Luthra R, Mehrotra M, Chen W, Barkoh BA, Hu P, Zhang W, Broaddus RR.

Mod Pathol. 2018 Oct 12. doi: 10.1038/s41379-018-0158-8. [Epub ahead of print]

PMID:
30315273
2.

Clinical molecular testing for ASXL1 c.1934dupG p.Gly646fs mutation in hematologic neoplasms in the NGS era.

Montes-Moreno S, Routbort MJ, Lohman EJ, Barkoh BA, Kanagal-Shamanna R, Bueso-Ramos CE, Singh RR, Medeiros LJ, Luthra R, Patel KP.

PLoS One. 2018 Sep 17;13(9):e0204218. doi: 10.1371/journal.pone.0204218. eCollection 2018.

3.

A phase 2 study of ruxolitinib in combination with azacitidine in patients with myelofibrosis.

Masarova L, Verstovsek S, Hidalgo-Lopez JE, Pemmaraju N, Bose P, Estrov Z, Jabbour EJ, Ravandi-Kashani F, Takahashi K, Cortes JE, Ning J, Ohanian M, Alvarado Y, Zhou L, Pierce S, Gergis R, Patel KP, Luthra R, Kadia TM, DiNardo CD, Borthakur G, Bhalla K, Garcia-Manero G, Bueso-Ramos CE, Kantarjian HM, Daver N.

Blood. 2018 Oct 18;132(16):1664-1674. doi: 10.1182/blood-2018-04-846626. Epub 2018 Sep 5.

PMID:
30185431
4.

Persistent IDH1/2 mutation in remission can predict relapse in patients with acute myeloid leukemia.

Ok CY, Loghavi S, Sui D, Wei P, Kanagal-Shamanna R, Yin CC, Zuo Z, Routbort MJ, Tang G, Tang Z, Jorgensen JL, Luthra R, Ravandi F, Kantarjian HM, DiNardo CD, Medeiros LJ, Wang SA, Patel KP.

Haematologica. 2018 Aug 31. pii: haematol.2018.191148. doi: 10.3324/haematol.2018.191148. [Epub ahead of print]

5.

Poorly differentiated osteoclast-like giant cell variant of cutaneous squamous cell carcinoma: Uncovering its mutational landscape through massive parallel sequencing.

Ahmadi Moghaddam P, Singh R, Mahmoodi M, Mehrotra M, Benaim G, Luthra R, Paniz-Mondolfi A.

Pathol Res Pract. 2018 Nov;214(11):1898-1903. doi: 10.1016/j.prp.2018.08.017. Epub 2018 Aug 19. No abstract available.

PMID:
30146254
6.

Chronic lymphocytic leukemia with proliferation centers in bone marrow is associated with younger age at initial presentation, complex karyotype and TP53 disruption.

Garces S, Khoury JD, Kanagal-Shamanna R, Salem A, Wang SA, Ok CY, Hu S, Patel KP, Routbort MJ, Luthra R, Tang G, Schlette EJ, Bueso-Ramos CE, Medeiros LJ, Loghavi S.

Hum Pathol. 2018 Aug 4. pii: S0046-8177(18)30298-3. doi: 10.1016/j.humpath.2018.07.030. [Epub ahead of print]

PMID:
30086334
7.

Higher body mass index is associated with better survival in patients with myelodysplastic syndromes.

Jabbar KJ, Yin CC, Bueso-Ramos CE, Luthra R, Medeiros LJ, Zuo Z.

Leuk Res. 2018 Aug;71:63-66. doi: 10.1016/j.leukres.2018.07.008. Epub 2018 Jul 10. No abstract available.

PMID:
30015105
8.

Challenges in next generation sequencing analysis of somatic mutations in transplant patients.

Chen H, Luthra R, Patel KP, Routbort M, Rashid A, Roy-Chowdhuri S, Lazar A, Broaddus R, Manekia J, Singh RR, Yemelyanova A.

Cancer Genet. 2018 Oct;226-227:17-22. doi: 10.1016/j.cancergen.2018.04.119. Epub 2018 May 10.

PMID:
30005850
9.

Evaluating Circulating Tumor DNA From the Cerebrospinal Fluid of Patients With Melanoma and Leptomeningeal Disease.

Ballester LY, Glitza Oliva IC, Douse DY, Chen MM, Lan C, Haydu LE, Huse JT, Roy-Chowdhuri S, Luthra R, Wistuba II, Davies MA.

J Neuropathol Exp Neurol. 2018 Jul 1;77(7):628-635. doi: 10.1093/jnen/nly046.

PMID:
29873738
10.

Molecular Profile of Advanced Thyroid Carcinomas by Next-Generation Sequencing: Characterizing Tumors Beyond Diagnosis for Targeted Therapy.

Chen H, Luthra R, Routbort MJ, Patel KP, Cabanillas ME, Broaddus RR, Williams MD.

Mol Cancer Ther. 2018 Jul;17(7):1575-1584. doi: 10.1158/1535-7163.MCT-17-0871. Epub 2018 Apr 25.

PMID:
29695638
11.

Improving the detection of patients with inherited predispositions to hematologic malignancies using next-generation sequencing-based leukemia prognostication panels.

DiNardo CD, Routbort MJ, Bannon SA, Benton CB, Takahashi K, Kornblau SM, Luthra R, Kanagal-Shamanna R, Medeiros LJ, Garcia-Manero G, M Kantarjian H, Futreal PA, Meric-Bernstam F, Patel KP.

Cancer. 2018 Jul 1;124(13):2704-2713. doi: 10.1002/cncr.31331. Epub 2018 Apr 6. Review.

PMID:
29682723
12.

Characterization of IDH1 p.R132H Mutant Clones Using Mutation-specific Antibody in Myeloid Neoplasms.

Kurt H, Bueso-Ramos CE, Khoury JD, Routbort MJ, Kanagal-Shamanna R, Patel UV, Jorgensen JL, Wang SA, Ravandi F, DiNardo C, Luthra R, Medeiros LJ, Patel KP.

Am J Surg Pathol. 2018 May;42(5):569-577. doi: 10.1097/PAS.0000000000000970.

PMID:
29635257
13.

MET amplification assessed using optimized FISH reporting criteria predicts early distant metastasis in patients with non-small cell lung cancer.

Fang L, Chen H, Tang Z, Kalhor N, Liu CH, Yao H, Hu S, Lin P, Zhao J, Luthra R, Singh RR, Routbort MJ, Hong D, Medeiros LJ, Lu X.

Oncotarget. 2018 Feb 7;9(16):12959-12970. doi: 10.18632/oncotarget.24430. eCollection 2018 Feb 27.

14.

Detection of somatic mutations in cell-free DNA in plasma and correlation with overall survival in patients with solid tumors.

Mehrotra M, Singh RR, Loghavi S, Duose DY, Barkoh BA, Behrens C, Patel KP, Routbort MJ, Kopetz S, Broaddus RR, Medeiros LJ, Wistuba II, Luthra R.

Oncotarget. 2017 Oct 24;9(12):10259-10271. doi: 10.18632/oncotarget.21982. eCollection 2018 Feb 13.

15.

Mixed phenotype acute leukemia contains heterogeneous genetic mutations by next-generation sequencing.

Quesada AE, Hu Z, Routbort MJ, Patel KP, Luthra R, Loghavi S, Zuo Z, Yin CC, Kanagal-Shamanna R, Wang SA, Jorgensen JL, Medeiros LJ, Ok CY.

Oncotarget. 2018 Jan 3;9(9):8441-8449. doi: 10.18632/oncotarget.23878. eCollection 2018 Feb 2.

16.

Characteristics and outcome of chronic myeloid leukemia patients with E255K/V BCR-ABL kinase domain mutations.

Naqvi K, Cortes JE, Luthra R, O'Brien S, Wierda W, Borthakur G, Kadia T, Garcia-Manero G, Ravandi F, Rios MB, Dellasala S, Pierce S, Jabbour E, Patel K, Kantarjian H.

Int J Hematol. 2018 Jun;107(6):689-695. doi: 10.1007/s12185-018-2422-6. Epub 2018 Feb 20.

PMID:
29464484
17.

Salvaging the supernatant: next generation cytopathology for solid tumor mutation profiling.

Roy-Chowdhuri S, Mehrotra M, Bolivar AM, Kanagal-Shamanna R, Barkoh BA, Hannigan B, Zalles S, Ye W, Duose D, Broaddus R, Staerkel G, Wistuba I, Medeiros LJ, Luthra R.

Mod Pathol. 2018 Jul;31(7):1036-1045. doi: 10.1038/s41379-018-0006-x. Epub 2018 Feb 20.

PMID:
29463880
18.

Characteristics of percutaneous core biopsies adequate for next generation genomic sequencing.

Sabir SH, Krishnamurthy S, Gupta S, Mills GB, Wei W, Cortes AC, Mills Shaw KR, Luthra R, Wallace MJ.

PLoS One. 2017 Dec 27;12(12):e0189651. doi: 10.1371/journal.pone.0189651. eCollection 2017.

19.

Sensitive PCR-based monitoring and early detection of relapsed JAK2 V617F myelofibrosis following transplantation.

Shah MV, Patel KP, Luthra R, Kanagal-Shamanna R, Mehrotra M, Bachegowda LS, Champlin RE, Verstovsek S, Popat UR.

Br J Haematol. 2017 Dec 19. doi: 10.1111/bjh.15059. [Epub ahead of print] No abstract available.

PMID:
29265180
20.

Prior systemic treatment increased the incidence of somatic mutations in metastatic breast cancer.

Fujii T, Matsuda N, Kono M, Harano K, Chen H, Luthra R, Roy-Chowdhuri S, Sahin AA, Wathoo C, Joon AY, Tripathy D, Meric-Bernstam F, Ueno NT.

Eur J Cancer. 2018 Jan;89:64-71. doi: 10.1016/j.ejca.2017.11.015. Epub 2017 Dec 9.

PMID:
29232568

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