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Complexity of the Ruminococcus flavefaciens cellulosome reflects an expansion in glycan recognition.

Venditto I, Luis AS, Rydahl M, Schückel J, Fernandes VO, Vidal-Melgosa S, Bule P, Goyal A, Pires VM, Dourado CG, Ferreira LM, Coutinho PM, Henrissat B, Knox JP, Baslé A, Najmudin S, Gilbert HJ, Willats WG, Fontes CM.

Proc Natl Acad Sci U S A. 2016 Jun 28;113(26):7136-41. doi: 10.1073/pnas.1601558113.


Family 46 Carbohydrate-binding Modules Contribute to the Enzymatic Hydrolysis of Xyloglucan and β-1,3-1,4-Glucans through Distinct Mechanisms.

Venditto I, Najmudin S, Luís AS, Ferreira LM, Sakka K, Knox JP, Gilbert HJ, Fontes CM.

J Biol Chem. 2015 Apr 24;290(17):10572-86. doi: 10.1074/jbc.M115.637827.


A curious case of exercise-induced wheat allergy in adulthood.

Carrapatoso I, Santos AF, Faria E, Luis AS.

J Investig Allergol Clin Immunol. 2014;24(1):64-5. No abstract available.


Mixed pneumoconiosis due to silicates and hard metals associated with primary Sjögren's syndrome due to silica.

Ferreira PG, Ferreira AJ, Carvalho LM, Luís AS.

J Bras Pneumol. 2014 Jan-Feb;40(1):92-5. doi: 10.1590/S1806-37132014000100016. English, Portuguese. No abstract available.


Impact of allergic rhinitis and specific subcutaneous immunotherapy on peripheral blood basophils of patients sensitized to Dermatophagoides pteronyssinus.

Lopes A, Azenha P, Teodósio C, Inácio M, Silva I, Loureiro G, Martinho A, Luís AS, Trindade H, Pereira C, Paiva A.

Allergy Asthma Clin Immunol. 2013 Oct 11;9(1):40. doi: 10.1186/1710-1492-9-40.


Functional and structural characterization of family 6 carbohydrate-binding module (CtCBM6A) of Clostridium thermocellum α-L-Arabinofuranosidase.

Ahmed S, Luís AS, Brás JL, Fontes CM, Goyal A.

Biochemistry (Mosc). 2013 Nov;78(11):1272-9. doi: 10.1134/S0006297913110072.


Deciphering ligand specificity of a Clostridium thermocellum family 35 carbohydrate binding module (CtCBM35) for gluco- and galacto- substituted mannans and its calcium induced stability.

Ghosh A, Luís AS, Brás JL, Pathaw N, Chrungoo NK, Fontes CM, Goyal A.

PLoS One. 2013 Dec 6;8(12):e80415. doi: 10.1371/journal.pone.0080415.


Pomegranate anaphylaxis due to cross-reactivity with Peach LTP (Pru p 3).

Almeida EM, Bartolomé B, Faria EG, Sousa NG, Luís AS.

Allergol Immunopathol (Madr). 2015 Jan-Feb;43(1):104-6. doi: 10.1016/j.aller.2013.07.013. No abstract available.


Thermostable recombinant β-(1→4)-mannanase from C. thermocellum: biochemical characterization and manno-oligosaccharides production.

Ghosh A, Luís AS, Brás JL, Fontes CM, Goyal A.

J Agric Food Chem. 2013 Dec 18;61(50):12333-44. doi: 10.1021/jf403111g.


A novel α-L-arabinofuranosidase of family 43 glycoside hydrolase (Ct43Araf) from Clostridium thermocellum.

Ahmed S, Luis AS, Bras JL, Ghosh A, Gautam S, Gupta MN, Fontes CM, Goyal A.

PLoS One. 2013 Sep 9;8(9):e73575. doi: 10.1371/journal.pone.0073575.


Overproduction, purification, crystallization and preliminary X-ray characterization of the C-terminal family 65 carbohydrate-binding module (CBM65B) of endoglucanase Cel5A from Eubacterium cellulosolvens.

Venditto I, Baslé A, Luís AS, Temple MJ, Ferreira LM, Fontes CM, Gilbert HJ, Najmudin S.

Acta Crystallogr Sect F Struct Biol Cryst Commun. 2013 Feb 1;69(Pt 2):191-4. doi: 10.1107/S1744309113001620.


Understanding how noncatalytic carbohydrate binding modules can display specificity for xyloglucan.

Luís AS, Venditto I, Temple MJ, Rogowski A, Baslé A, Xue J, Knox JP, Prates JA, Ferreira LM, Fontes CM, Najmudin S, Gilbert HJ.

J Biol Chem. 2013 Feb 15;288(7):4799-809. doi: 10.1074/jbc.M112.432781.


The epigenetics of renal cell tumors: from biology to biomarkers.

Henrique R, Luís AS, Jerónimo C.

Front Genet. 2012 May 30;3:94. doi: 10.3389/fgene.2012.00094.


Influence of a mannan binding family 32 carbohydrate binding module on the activity of the appended mannanase.

Mizutani K, Fernandes VO, Karita S, Luís AS, Sakka M, Kimura T, Jackson A, Zhang X, Fontes CM, Gilbert HJ, Sakka K.

Appl Environ Microbiol. 2012 Jul;78(14):4781-7. doi: 10.1128/AEM.07457-11.


Streptococcal tonsillitis as a cause of urticaria: tonsillitis and urticaria.

Calado G, Loureiro G, Machado D, Tavares B, Ribeiro C, Pereira C, Luís AS.

Allergol Immunopathol (Madr). 2012 Nov-Dec;40(6):341-5. doi: 10.1016/j.aller.2011.06.008.


Overproduction, purification, crystallization and preliminary X-ray characterization of a novel carbohydrate-binding module of endoglucanase Cel5A from Eubacterium cellulosolvens.

Luís AS, Alves VD, Romão MJ, Prates JA, Fontes CM, Najmudin S.

Acta Crystallogr Sect F Struct Biol Cryst Commun. 2011 Apr 1;67(Pt 4):491-3. doi: 10.1107/S1744309111004246.


Rimonabant for prevention of cardiovascular events (CRESCENDO): a randomised, multicentre, placebo-controlled trial.

Topol EJ, Bousser MG, Fox KA, Creager MA, Despres JP, Easton JD, Hamm CW, Montalescot G, Steg PG, Pearson TA, Cohen E, Gaudin C, Job B, Murphy JH, Bhatt DL; CRESCENDO Investigators..

Lancet. 2010 Aug 14;376(9740):517-23. doi: 10.1016/S0140-6736(10)60935-X.


Family 42 carbohydrate-binding modules display multiple arabinoxylan-binding interfaces presenting different ligand affinities.

Ribeiro T, Santos-Silva T, Alves VD, Dias FM, Luís AS, Prates JA, Ferreira LM, Romão MJ, Fontes CM.

Biochim Biophys Acta. 2010 Oct;1804(10):2054-62. doi: 10.1016/j.bbapap.2010.07.006.


[Epithelioid hemangioendothelioma of the pleura - A rare presentation of a clinical case].

André ST, Valente C, Paiva B, Pêgo A, Carvalho L, Luís AS.

Rev Port Pneumol. 2010 May-Jun;16(3):477-82. Portuguese.



Luís AS.

Rev Port Pneumol. 2009 Nov;15 Suppl 2:S5-7. doi: 10.1016/S0873-2159(15)30212-9. English, Portuguese. No abstract available.

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