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Items: 1 to 20 of 22


α-MSH modulates cell adhesion and inflammatory responses of synovial fibroblasts from osteoarthritis patients.

Böhm M, Apel M, Lowin T, Lorenz J, Jenei-Lanzl Z, Capellino S, Dosoki H, Luger TA, Straub RH, Grässel S.

Biochem Pharmacol. 2016 Sep 15;116:89-99. doi: 10.1016/j.bcp.2016.07.003. Epub 2016 Jul 7.


Peripheral elimination of the sympathetic nervous system stimulates immunocyte retention in lymph nodes and ameliorates collagen type II arthritis.

Klatt S, Stangl H, Kunath J, Lowin T, Pongratz G, Straub RH.

Brain Behav Immun. 2016 May;54:201-210. doi: 10.1016/j.bbi.2016.02.006. Epub 2016 Feb 9.


Anti-inflammatory effects of N-acylethanolamines in rheumatoid arthritis synovial cells are mediated by TRPV1 and TRPA1 in a COX-2 dependent manner.

Lowin T, Apitz M, Anders S, Straub RH.

Arthritis Res Ther. 2015 Nov 14;17:321. doi: 10.1186/s13075-015-0845-5.


A sustained high fat diet for two years decreases IgM and IL-1 beta in ageing Wistar rats.

Pongratz G, Lowin T, Kob R, Buettner R, Bertsch T, Bollheimer LC.

Immun Ageing. 2015 Sep 28;12:12. doi: 10.1186/s12979-015-0040-1. eCollection 2015.


Cannabinoid-based drugs targeting CB1 and TRPV1, the sympathetic nervous system, and arthritis.

Lowin T, Straub RH.

Arthritis Res Ther. 2015 Sep 6;17:226. doi: 10.1186/s13075-015-0743-x. Review.


Proinflammatory receptor switch from Gαs to Gαi signaling by β-arrestin-mediated PDE4 recruitment in mixed RA synovial cells.

Jenei-Lanzl Z, Zwingenberg J, Lowin T, Anders S, Straub RH.

Brain Behav Immun. 2015 Nov;50:266-274. doi: 10.1016/j.bbi.2015.07.020. Epub 2015 Jul 23.


Synovial fibroblasts integrate inflammatory and neuroendocrine stimuli to drive rheumatoid arthritis.

Lowin T, Straub RH.

Expert Rev Clin Immunol. 2015;11(10):1069-71. doi: 10.1586/1744666X.2015.1066674. Epub 2015 Jul 10. Review.


Increased expression of dopamine receptors in synovial fibroblasts from patients with rheumatoid arthritis: inhibitory effects of dopamine on interleukin-8 and interleukin-6.

Capellino S, Cosentino M, Luini A, Bombelli R, Lowin T, Cutolo M, Marino F, Straub RH.

Arthritis Rheumatol. 2014 Oct;66(10):2685-93. doi: 10.1002/art.38746.


Anti-inflammatory effects of cell-based therapy with tyrosine hydroxylase-positive catecholaminergic cells in experimental arthritis.

Jenei-Lanzl Z, Capellino S, Kees F, Fleck M, Lowin T, Straub RH.

Ann Rheum Dis. 2015 Feb;74(2):444-51. doi: 10.1136/annrheumdis-2013-203925. Epub 2013 Dec 2.


Cortisol-mediated adhesion of synovial fibroblasts is dependent on the degradation of anandamide and activation of the endocannabinoid system.

Lowin T, Zhu W, Dettmer-Wilde K, Straub RH.

Arthritis Rheum. 2012 Dec;64(12):3867-76. doi: 10.1002/art.37684.


Relationship between placenta growth factor 1 and vascularization, dehydroepiandrosterone sulfate to dehydroepiandrosterone conversion, or aromatase expression in patients with rheumatoid arthritis and patients with osteoarthritis.

Lowin T, Weidler C, Jenei-Lanzl Z, Capellino S, Baerwald CG, Buttgereit F, Straub RH.

Arthritis Rheum. 2012 Jun;64(6):1799-808. doi: 10.1002/art.34338. Epub 2011 Dec 14.


Integrins and their ligands in rheumatoid arthritis.

Lowin T, Straub RH.

Arthritis Res Ther. 2011;13(5):244. doi: 10.1186/ar3464. Epub 2011 Oct 28. Review.


Increased density of sympathetic nerve fibers in metabolically activated fat tissue surrounding human synovium and mouse lymph nodes in arthritis.

Straub RH, Lowin T, Klatt S, Wolff C, Rauch L.

Arthritis Rheum. 2011 Nov;63(11):3234-42. doi: 10.1002/art.30516.


RAP-PCR fingerprinting reveals time-dependent expression of matrix-related molecules following stem-cell based TGFβ1-induced chondrocyte development.

Schedel J, Lowin T, Kujat R, Judex M, Schölmerich J, Nerlich M, Müller-Ladner U, Angele P.

Int J Mol Med. 2011 Apr;27(4):519-23. doi: 10.3892/ijmm.2011.608. Epub 2011 Feb 1.


Slit3 inhibits Robo3-induced invasion of synovial fibroblasts in rheumatoid arthritis.

Denk AE, Kaufmann S, Stark K, Schedel J, Lowin T, Schubert T, Bosserhoff AK.

Arthritis Res Ther. 2010;12(2):R45. doi: 10.1186/ar2955. Epub 2010 Mar 18.


Glucocorticoids increase alpha5 integrin expression and adhesion of synovial fibroblasts but inhibit ERK signaling, migration, and cartilage invasion.

Lowin T, Straub RH, Neumann E, Bosserhoff A, Vogel C, Moissl C, Anders S, Müller-Ladner U, Schedel J.

Arthritis Rheum. 2009 Dec;60(12):3623-32. doi: 10.1002/art.24985.


Role of the netrin system of repellent factors on synovial fibroblasts in rheumatoid arthritis and osteoarthritis.

Schubert T, Denk A, Mägdefrau U, Kaufmann S, Bastone P, Lowin T, Schedel J, Bosserhoff AK.

Int J Immunopathol Pharmacol. 2009 Jul-Sep;22(3):715-22.


Neuronally released sympathetic neurotransmitters stimulate splenic interferon-gamma secretion from T cells in early type II collagen-induced arthritis.

Straub RH, Rauch L, Fassold A, Lowin T, Pongratz G.

Arthritis Rheum. 2008 Nov;58(11):3450-60. doi: 10.1002/art.24030. Erratum in: Arthritis Rheum. 2012 May;64(5):1695-6.


Increased chromogranin A levels indicate sympathetic hyperactivity in patients with rheumatoid arthritis and systemic lupus erythematosus.

Capellino S, Lowin T, Angele P, Falk W, Grifka J, Straub RH.

J Rheumatol. 2008 Jan;35(1):91-9. Epub 2007 Dec 1.


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