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Items: 1 to 20 of 83


Structural Alterations Driving Castration-Resistant Prostate Cancer Revealed by Linked-Read Genome Sequencing.

Viswanathan SR, Ha G, Hoff AM, Wala JA, Carrot-Zhang J, Whelan CW, Haradhvala NJ, Freeman SS, Reed SC, Rhoades J, Polak P, Cipicchio M, Wankowicz SA, Wong A, Kamath T, Zhang Z, Gydush GJ, Rotem D; PCF/SU2C International Prostate Cancer Dream Team, Love JC, Getz G, Gabriel S, Zhang CZ, Dehm SM, Nelson PS, Van Allen EM, Choudhury AD, Adalsteinsson VA, Beroukhim R, Taplin ME, Meyerson M.

Cell. 2018 Jul 12;174(2):433-447.e19. doi: 10.1016/j.cell.2018.05.036. Epub 2018 Jun 18.


An impurity characterization based approach for the rapid development of integrated downstream purification processes.

Timmick SM, Vecchiarello N, Goodwine C, Crowell LE, Love KR, Love JC, Cramer SM.

Biotechnol Bioeng. 2018 Aug;115(8):2048-2060. doi: 10.1002/bit.26718. Epub 2018 May 4.


Association of Cell-Free DNA Tumor Fraction and Somatic Copy Number Alterations With Survival in Metastatic Triple-Negative Breast Cancer.

Stover DG, Parsons HA, Ha G, Freeman SS, Barry WT, Guo H, Choudhury AD, Gydush G, Reed SC, Rhoades J, Rotem D, Hughes ME, Dillon DA, Partridge AH, Wagle N, Krop IE, Getz G, Golub TR, Love JC, Winer EP, Tolaney SM, Lin NU, Adalsteinsson VA.

J Clin Oncol. 2018 Feb 20;36(6):543-553. doi: 10.1200/JCO.2017.76.0033. Epub 2018 Jan 3.


The yeast stands alone: the future of protein biologic production.

Love KR, Dalvie NC, Love JC.

Curr Opin Biotechnol. 2017 Dec 22;53:50-58. doi: 10.1016/j.copbio.2017.12.010. [Epub ahead of print] Review.


Erythrocyte efferocytosis modulates macrophages towards recovery after intracerebral hemorrhage.

Chang CF, Goods BA, Askenase MH, Hammond MD, Renfroe SC, Steinschneider AF, Landreneau MJ, Ai Y, Beatty HE, da Costa LHA, Mack M, Sheth KN, Greer DM, Huttner A, Coman D, Hyder F, Ghosh S, Rothlin CV, Love JC, Sansing LH.

J Clin Invest. 2018 Feb 1;128(2):607-624. doi: 10.1172/JCI95612. Epub 2017 Dec 18.


Cover Image, Volume 115, Number 1, January 2018.

Matthews CB, Kuo A, Love KR, Love JC.

Biotechnol Bioeng. 2018 Jan;115(1):i. doi: 10.1002/bit.26409.


Cell-type Dependent Alzheimer's Disease Phenotypes: Probing the Biology of Selective Neuronal Vulnerability.

Muratore CR, Zhou C, Liao M, Fernandez MA, Taylor WM, Lagomarsino VN, Pearse RV 2nd, Rice HC, Negri JM, He A, Srikanth P, Callahan DG, Shin T, Zhou M, Bennett DA, Noggle S, Love JC, Selkoe DJ, Young-Pearse TL.

Stem Cell Reports. 2017 Dec 12;9(6):1868-1884. doi: 10.1016/j.stemcr.2017.10.015. Epub 2017 Nov 16.


Scalable whole-exome sequencing of cell-free DNA reveals high concordance with metastatic tumors.

Adalsteinsson VA, Ha G, Freeman SS, Choudhury AD, Stover DG, Parsons HA, Gydush G, Reed SC, Rotem D, Rhoades J, Loginov D, Livitz D, Rosebrock D, Leshchiner I, Kim J, Stewart C, Rosenberg M, Francis JM, Zhang CZ, Cohen O, Oh C, Ding H, Polak P, Lloyd M, Mahmud S, Helvie K, Merrill MS, Santiago RA, O'Connor EP, Jeong SH, Leeson R, Barry RM, Kramkowski JF, Zhang Z, Polacek L, Lohr JG, Schleicher M, Lipscomb E, Saltzman A, Oliver NM, Marini L, Waks AG, Harshman LC, Tolaney SM, Van Allen EM, Winer EP, Lin NU, Nakabayashi M, Taplin ME, Johannessen CM, Garraway LA, Golub TR, Boehm JS, Wagle N, Getz G, Love JC, Meyerson M.

Nat Commun. 2017 Nov 6;8(1):1324. doi: 10.1038/s41467-017-00965-y.


Integrated Bottom-Up and Top-Down Liquid Chromatography-Mass Spectrometry for Characterization of Recombinant Human Growth Hormone Degradation Products.

Wang YA, Wu D, Auclair JR, Salisbury JP, Sarin R, Tang Y, Mozdzierz NJ, Shah K, Zhang AF, Wu SL, Agar JN, Love JC, Love KR, Hancock WS.

Anal Chem. 2017 Dec 5;89(23):12771-12777. doi: 10.1021/acs.analchem.7b03026. Epub 2017 Nov 21.


Longitudinal multiparameter single-cell analysis of macaques immunized with pneumococcal protein-conjugated or unconjugated polysaccharide vaccines reveals distinct antigen specific memory B cell repertoires.

Jia B, McNeil LK, Dupont CD, Tsioris K, Barry RM, Scully IL, Ogunniyi AO, Gonzalez C, Pride MW, Gierahn TM, Liberator PA, Jansen KU, Love JC.

PLoS One. 2017 Sep 14;12(9):e0183738. doi: 10.1371/journal.pone.0183738. eCollection 2017.


Functional differences between PD-1+ and PD-1- CD4+ effector T cells in healthy donors and patients with glioblastoma multiforme.

Goods BA, Hernandez AL, Lowther DE, Lucca LE, Lerner BA, Gunel M, Raddassi K, Coric V, Hafler DA, Love JC.

PLoS One. 2017 Sep 7;12(9):e0181538. doi: 10.1371/journal.pone.0181538. eCollection 2017.


Development of a general defined medium for Pichia pastoris.

Matthews CB, Kuo A, Love KR, Love JC.

Biotechnol Bioeng. 2018 Jan;115(1):103-113. doi: 10.1002/bit.26440. Epub 2017 Oct 6.


Reexamining opportunities for therapeutic protein production in eukaryotic microorganisms.

Matthews CB, Wright C, Kuo A, Colant N, Westoby M, Love JC.

Biotechnol Bioeng. 2017 Nov;114(11):2432-2444. doi: 10.1002/bit.26378. Epub 2017 Aug 17. Review.


A method for learning a sparse classifier in the presence of missing data for high-dimensional biological datasets.

Severson KA, Monian B, Love JC, Braatz RD.

Bioinformatics. 2017 Sep 15;33(18):2897-2905. doi: 10.1093/bioinformatics/btx224.


Seq-Well: portable, low-cost RNA sequencing of single cells at high throughput.

Gierahn TM, Wadsworth MH 2nd, Hughes TK, Bryson BD, Butler A, Satija R, Fortune S, Love JC, Shalek AK.

Nat Methods. 2017 Apr;14(4):395-398. doi: 10.1038/nmeth.4179. Epub 2017 Feb 13.


Diversity of Antiviral IgG Effector Activities Observed in HIV-Infected and Vaccinated Subjects.

Huang Y, Ferrari G, Alter G, Forthal DN, Kappes JC, Lewis GK, Love JC, Borate B, Harris L, Greene K, Gao H, Phan TB, Landucci G, Goods BA, Dowell KG, Cheng HD, Bailey-Kellogg C, Montefiori DC, Ackerman ME.

J Immunol. 2016 Dec 15;197(12):4603-4612. Epub 2016 Nov 9.


TGF-╬▓1 modulates microglial phenotype and promotes recovery after intracerebral hemorrhage.

Taylor RA, Chang CF, Goods BA, Hammond MD, Mac Grory B, Ai Y, Steinschneider AF, Renfroe SC, Askenase MH, McCullough LD, Kasner SE, Mullen MT, Hafler DA, Love JC, Sansing LH.

J Clin Invest. 2017 Jan 3;127(1):280-292. doi: 10.1172/JCI88647. Epub 2016 Nov 28.


Single-cell analysis at the threshold.

Chen X, Love JC, Navin NE, Pachter L, Stubbington MJ, Svensson V, Sweedler JV, Teichmann SA.

Nat Biotechnol. 2016 Nov 8;34(11):1111-1118. doi: 10.1038/nbt.3721. No abstract available.


Erratum to: Comparative genomics and transcriptomics of Pichia pastoris.

Love KR, Shah KA, Whittaker CA, Wu J, Bartlett MC, Ma D, Leeson RL, Priest M, Borowsky J, Young SK, Love JC.

BMC Genomics. 2016 Sep 28;17(1):762. No abstract available.


A Size-Selective Intracellular Delivery Platform.

Saung MT, Sharei A, Adalsteinsson VA, Cho N, Kamath T, Ruiz C, Kirkpatrick J, Patel N, Mino-Kenudson M, Thayer SP, Langer R, Jensen KF, Liss AS, Love JC.

Small. 2016 Sep 4. doi: 10.1002/smll.201601155. [Epub ahead of print]

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