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Items: 1 to 20 of 215


Clinical evaluation of modifications to a human papillomavirus assay to optimise its utility for cervical cancer screening in low-resource settings: a diagnostic accuracy study.

Kuhn L, Saidu R, Boa R, Tergas A, Moodley J, Persing D, Campbell S, Tsai WY, Wright TC, Denny L.

Lancet Glob Health. 2020 Feb;8(2):e296-e304. doi: 10.1016/S2214-109X(19)30527-3.


Early Infant Treatment: Still a long way to go to reach HIV remission.

Kuhn L.

Clin Infect Dis. 2020 Jan 11. pii: ciaa033. doi: 10.1093/cid/ciaa033. [Epub ahead of print] No abstract available.


Negative diagnostic PCR tests in school-aged, HIV-infected children on antiretroviral therapy since early life in Johannesburg, South Africa.

Patel F, Thurman C, Liberty A, Burke M, Strehlau R, Shiau S, Coovadia A, Abrams EJ, Violari A, Kuhn L.

J Acquir Immune Defic Syndr. 2020 Jan 6. doi: 10.1097/QAI.0000000000002265. [Epub ahead of print]


Reduced Time to Suppression Among Neonates With HIV Initiating Antiretroviral Therapy Within 7 Days After Birth.

Domínguez-Rodríguez S, Tagarro A, Palma P, Foster C, Puthanakit T, Jupimai T, Cotugno N, Ananworanich J, Zangari P, Nastouli E, Muñoz-Fernández MÁ, Navarro ML, Giaquinto C, Rossi P, Kuhn L, Rojo P.

J Acquir Immune Defic Syndr. 2019 Dec 15;82(5):483-490. doi: 10.1097/QAI.0000000000002188.


Effect of co-trimoxazole prophylaxis on morbidity and mortality of HIV-exposed, HIV-uninfected infants in South Africa: a randomised controlled, non-inferiority trial.

Daniels B, Coutsoudis A, Moodley-Govender E, Mulol H, Spooner E, Kiepiela P, Reddy S, Zako L, Ho NT, Kuhn L, Ramjee G.

Lancet Glob Health. 2019 Dec;7(12):e1717-e1727. doi: 10.1016/S2214-109X(19)30422-X.


Moving towards elimination: findings from the South Africa prevention of mother to child transmission evaluation (SAPMTCTE).

Kuhn L, Goga AE.

BMC Infect Dis. 2019 Sep 16;19(Suppl 1):782. doi: 10.1186/s12879-019-4334-3. No abstract available.


Sequential tests of promise with discrete time-to-event data.

Levin B, Kuhn L, Leu CS, Tsai WY.

Contemp Clin Trials. 2019 Oct;85:105818. doi: 10.1016/j.cct.2019.105818. Epub 2019 Aug 21.


Cost-Effectiveness of Preemptive Switching to Efavirenz-Based Antiretroviral Therapy for Children With Human Immunodeficiency Virus.

Desmonde S, Frank SC, Coovadia A, Dahourou DL, Hou T, Abrams EJ, Amorissani-Folquet M, Walensky RP, Strehlau R, Penazzato M, Freedberg KA, Kuhn L, Leroy V, Ciaranello AL.

Open Forum Infect Dis. 2019 Jun 11;6(7):ofz276. doi: 10.1093/ofid/ofz276. eCollection 2019 Jul.


Distinct epigenetic profiles in children with perinatally-acquired HIV on antiretroviral therapy.

Shiau S, Strehlau R, Wang S, Violari A, Do C, Patel F, Liberty A, Krupska I, Arpadi SM, Foca M, Coovadia A, Abrams EJ, Tycko B, Terry MB, Kuhn L.

Sci Rep. 2019 Jul 19;9(1):10495. doi: 10.1038/s41598-019-46930-1.


Educational delays among children living with perinatally-acquired HIV in Johannesburg, South Africa.

Shiau S, Arpadi SM, Burke M, Liberty A, Thurman C, Patel F, Strehlau R, Abrams EJ, Coovadia A, Violari A, Kuhn L.

AIDS Care. 2019 Jul 9:1-7. doi: 10.1080/09540121.2019.1640854. [Epub ahead of print]


Impact of Shifts to Birth Testing on Early Infant Diagnosis Program Outcomes in KwaZulu-Natal, South Africa.

Smith S, Govender K, Moodley P, La Russa P, Kuhn L, Archary M.

Pediatr Infect Dis J. 2019 Jul;38(7):e138-e142. doi: 10.1097/INF.0000000000002341.


Perforin gene PRF1 c.900C> T polymorphism and HIV-1 vertical transmission.

Zupin L, Polesello V, Kamada AJ, Gratton R, Segat L, Kuhn L, Crovella S.

Genet Mol Biol. 2019 Jul-Sep;42(3):574-577. doi: 10.1590/1678-4685-GMB-2018-0243. Epub 2019 Nov 14.


Mitochondrial Impairment in Well-Suppressed Children with Perinatal HIV-Infection on Antiretroviral Therapy.

Shen J, Liberty A, Shiau S, Strehlau R, Pierson S, Patel F, Wang L, Burke M, Violari A, Coovadia A, Abrams EJ, Arpadi S, Foca M, Kuhn L.

AIDS Res Hum Retroviruses. 2020 Jan;36(1):27-38. doi: 10.1089/AID.2018.0182. Epub 2019 Jul 15.


HIV diagnostic challenges in breast-fed infants of mothers on antiretroviral therapy.

Strehlau R, Paximadis M, Patel F, Burke M, Technau KG, Shiau S, Abrams EJ, Sherman GG, Hunt G, Ledwaba J, Mazanderani AH, Tiemessen CT, Kuhn L; LEOPARD Study Team.

AIDS. 2019 Sep 1;33(11):1751-1756. doi: 10.1097/QAD.0000000000002276.


Early infant diagnosis HIV-1 PCR cycle-threshold predicts infant viral load at birth.

Haeri Mazanderani A, Kufa T, Technau KG, Strehlau R, Patel F, Shiau S, Burke M, Kuhn L, Abrams EJ, Sherman GG; LEOPARD Study Team.

J Clin Virol. 2019 May;114:21-25. doi: 10.1016/j.jcv.2019.03.009. Epub 2019 Mar 18.


A child with perinatal HIV infection and long-term sustained virological control following antiretroviral treatment cessation.

Violari A, Cotton MF, Kuhn L, Schramm DB, Paximadis M, Loubser S, Shalekoff S, Da Costa Dias B, Otwombe K, Liberty A, McIntyre J, Babiker A, Gibb D, Tiemessen CT.

Nat Commun. 2019 Jan 24;10(1):412. doi: 10.1038/s41467-019-08311-0.


Complementary feeding intervention benefits HIV-exposed uninfected children.

Kuhn L.

Lancet Child Adolesc Health. 2019 Feb;3(2):56-57. doi: 10.1016/S2352-4642(18)30372-9. Epub 2018 Dec 18. No abstract available.


12-month outcomes of HIV-infected infants identified at birth at one maternity site in Johannesburg, South Africa: an observational cohort study.

Technau KG, Strehlau R, Patel F, Shiau S, Burke M, Conradie M, Sorour G, Sherman GG, Coovadia A, Murnane PM, Abrams EJ, Kuhn L.

Lancet HIV. 2018 Dec;5(12):e706-e714. doi: 10.1016/S2352-3018(18)30251-0. Epub 2018 Nov 8.


Meta-analysis of effects of exclusive breastfeeding on infant gut microbiota across populations.

Ho NT, Li F, Lee-Sarwar KA, Tun HM, Brown BP, Pannaraj PS, Bender JM, Azad MB, Thompson AL, Weiss ST, Azcarate-Peril MA, Litonjua AA, Kozyrskyj AL, Jaspan HB, Aldrovandi GM, Kuhn L.

Nat Commun. 2018 Oct 9;9(1):4169. doi: 10.1038/s41467-018-06473-x.

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