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Items: 1 to 20 of 126

1.

Cartilage microRNA dysregulation during the onset and progression of mouse osteoarthritis is independent of aggrecanolysis and overlaps with candidates from end-stage human disease.

Kung LHW, Ravi V, Rowley L, Angelucci C, Fosang AJ, Bell KM, Little CB, Bateman JF.

Arthritis Rheumatol. 2017 Nov 16. doi: 10.1002/art.40378. [Epub ahead of print]

PMID:
29145712
2.

Biomarkers for equine joint injury and osteoarthritis.

McIlwraith CW, Kawcak CE, Frisbie DD, Little CB, Clegg PD, Peffers MJ, Karsdal MA, Ekman S, Laverty S, Slayden RA, Sandell LJ, Lohmander LS, Kraus VB.

J Orthop Res. 2017 Sep 16. doi: 10.1002/jor.23738. [Epub ahead of print] Review.

PMID:
28921609
3.
4.

Bioengineered Temporomandibular Joint Disk Implants: Study Protocol for a Two-Phase Exploratory Randomized Preclinical Pilot Trial in 18 Black Merino Sheep (TEMPOJIMS).

Ângelo DF, Monje FG, González-García R, Little CB, Mónico L, Pinho M, Santos FA, Carrapiço B, Gonçalves SC, Morouço P, Alves N, Moura C, Wang Y, Jeffries E, Gao J, Sousa R, Neto LL, Caldeira D, Salvado F.

JMIR Res Protoc. 2017 Mar 2;6(3):e37. doi: 10.2196/resprot.6779.

5.

The biology of meniscal pathology in osteoarthritis and its contribution to joint disease: beyond simple mechanics.

Melrose J, Fuller ES, Little CB.

Connect Tissue Res. 2017 May - Jul;58(3-4):282-294. doi: 10.1080/03008207.2017.1284824. Epub 2017 Jan 25.

PMID:
28121190
6.

Use of FGF-2 and FGF-18 to direct bone marrow stromal stem cells to chondrogenic and osteogenic lineages.

Shu C, Smith SM, Little CB, Melrose J.

Future Sci OA. 2016 Sep 22;2(4):FSO142. doi: 10.4155/fsoa-2016-0034. eCollection 2016 Dec.

7.

Considerations for the design and execution of protocols for animal research and treatment to improve reproducibility and standardization: "DEPART well-prepared and ARRIVE safely".

Smith MM, Clarke EC, Little CB.

Osteoarthritis Cartilage. 2017 Mar;25(3):354-363. doi: 10.1016/j.joca.2016.10.016. Epub 2016 Nov 2.

PMID:
27816577
8.

Hyaluronan oligosaccharides stimulate matrix metalloproteinase and anabolic gene expression in vitro by intervertebral disc cells and annular repair in vivo.

Fuller ES, Shu C, Smith MM, Little CB, Melrose J.

J Tissue Eng Regen Med. 2016 Sep 30. doi: 10.1002/term.2319. [Epub ahead of print]

PMID:
27689852
9.

Utility of circulating serum miRNAs as biomarkers of early cartilage degeneration in animal models of post-traumatic osteoarthritis and inflammatory arthritis.

Kung LH, Zaki S, Ravi V, Rowley L, Smith MM, Bell KM, Bateman JF, Little CB.

Osteoarthritis Cartilage. 2017 Mar;25(3):426-434. doi: 10.1016/j.joca.2016.09.002. Epub 2016 Sep 9.

PMID:
27621213
10.

Interleukin-1α induces focal degradation of biglycan and tissue degeneration in an in-vitro ovine meniscal model.

Fuller E, Little CB, Melrose J.

Exp Mol Pathol. 2016 Oct;101(2):214-220. doi: 10.1016/j.yexmp.2016.09.001. Epub 2016 Sep 9.

PMID:
27615609
11.

Joint loads resulting in ACL rupture: Effects of age, sex, and body mass on injury load and mode of failure in a mouse model.

Blaker CL, Little CB, Clarke EC.

J Orthop Res. 2017 Aug;35(8):1754-1763. doi: 10.1002/jor.23418. Epub 2016 Sep 19.

PMID:
27601010
12.

Pericellular colocalisation and interactive properties of type VI collagen and perlecan in the intervertebral disc.

Hayes AJ, Shu CC, Lord MS, Little CB, Whitelock JM, Melrose J.

Eur Cell Mater. 2016 Jul 5;32:40-57.

13.

Reoxygenation enhances tumour necrosis factor alpha-induced degradation of the extracellular matrix produced by chondrogenic cells.

Markway BD, Cho H, Anderson DE, Holden P, Ravi V, Little CB, Johnstone B.

Eur Cell Mater. 2016 Jun 24;31:425-39.

14.

Chondroitin sulphate glycosaminoglycans contribute to widespread inferior biomechanics in tendon after focal injury.

Choi RK, Smith MM, Martin JH, Clarke JL, Dart AJ, Little CB, Clarke EC.

J Biomech. 2016 Sep 6;49(13):2694-2701. doi: 10.1016/j.jbiomech.2016.06.006. Epub 2016 Jun 6.

PMID:
27316761
15.

Using mouse models to investigate the pathophysiology, treatment, and prevention of post-traumatic osteoarthritis.

Blaker CL, Clarke EC, Little CB.

J Orthop Res. 2017 Mar;35(3):424-439. doi: 10.1002/jor.23343. Epub 2016 Jun 28. Review.

PMID:
27312470
16.

Mesenchymal Stem Cell Treatment of Intervertebral Disc Lesion Prevents Fatty Infiltration and Fibrosis of the Multifidus Muscle, but not Cytokine and Muscle Fiber Changes.

James G, Blomster L, Hall L, Schmid AB, Shu CC, Little CB, Melrose J, Hodges PW.

Spine (Phila Pa 1976). 2016 Aug 1;41(15):1208-17. doi: 10.1097/BRS.0000000000001669.

PMID:
27135642
17.

The CS Sulfation Motifs 4C3, 7D4, 3B3[-]; and Perlecan Identify Stem Cell Populations and Their Niches, Activated Progenitor Cells and Transitional Areas of Tissue Development in the Fetal Human Elbow.

Hayes AJ, Hughes CE, Smith SM, Caterson B, Little CB, Melrose J.

Stem Cells Dev. 2016 Jun 1;25(11):836-47. doi: 10.1089/scd.2016.0054. Epub 2016 May 5.

PMID:
27068010
18.

Correction: Focal Experimental Injury Leads to Widespread Gene Expression and Histologic Changes in Equine Flexor Tendons.

Jacobson E, Dart AJ, Mondori T, Horadogoda N, Jeffcott LB, Little CB, Smith MM.

PLoS One. 2016 Mar 1;11(3):e0150823. doi: 10.1371/journal.pone.0150823. eCollection 2016. No abstract available.

19.

Effect of Manuka honey gel on the transforming growth factor β1 and β3 concentrations, bacterial counts and histomorphology of contaminated full-thickness skin wounds in equine distal limbs.

Bischofberger AS, Dart CM, Horadagoda N, Perkins NR, Jeffcott LB, Little CB, Dart AJ.

Aust Vet J. 2016 Jan-Feb;94(1-2):27-34. doi: 10.1111/avj.12405.

PMID:
26814159
20.

The great debate: Should Osteoarthritis Research Focus on "Mice" or "Men"?

Hunter DJ, Little CB.

Osteoarthritis Cartilage. 2016 Jan;24(1):4-8. doi: 10.1016/j.joca.2015.07.029. No abstract available.

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