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Items: 1 to 20 of 24

1.

Human Germline Hedgehog Pathway Mutations Predispose to Fatty Liver.

Sacoto MJG, Martinez AF, Abe Y, Kruszka P, Weiss K, Everson JL, Bataller R, Kleiner DE, Ward JM, Sulik KK, Lipinski RJ, Solomon BD, Muenke M.

J Hepatol. 2017 Jun 20. pii: S0168-8278(17)32078-0. doi: 10.1016/j.jhep.2017.06.008. [Epub ahead of print]

PMID:
28645738
2.

Sonic hedgehog regulation of Foxf2 promotes cranial neural crest mesenchyme proliferation and is disrupted in cleft lip morphogenesis.

Everson JL, Fink DM, Yoon JW, Leslie EJ, Kietzman HW, Ansen-Wilson LJ, Chung HM, Walterhouse DO, Marazita ML, Lipinski RJ.

Development. 2017 Jun 1;144(11):2082-2091. doi: 10.1242/dev.149930. Epub 2017 May 15.

PMID:
28506991
3.

Gene-environment interactions in cortical interneuron development and dysfunction: A review of preclinical studies.

Ansen-Wilson LJ, Lipinski RJ.

Neurotoxicology. 2017 Jan;58:120-129. doi: 10.1016/j.neuro.2016.12.002. Epub 2016 Dec 5. Review.

PMID:
27932026
4.

Gli2 gene-environment interactions contribute to the etiological complexity of holoprosencephaly: evidence from a mouse model.

Heyne GW, Everson JL, Ansen-Wilson LJ, Melberg CG, Fink DM, Parins KF, Doroodchi P, Ulschmid CM, Lipinski RJ.

Dis Model Mech. 2016 Nov 1;9(11):1307-1315. Epub 2016 Sep 1.

5.

A Simple and Reliable Method for Early Pregnancy Detection in Inbred Mice.

Heyne GW, Plisch EH, Melberg CG, Sandgren EP, Peter JA, Lipinski RJ.

J Am Assoc Lab Anim Sci. 2015 Jul;54(4):368-71.

6.

35(th) Annual David W Smith Workshop on Malformations and Morphogenesis: abstracts of the 2014 annual meeting.

Braddock SR, Lipinski RJ, Williams MS, Carey JC.

Am J Med Genet A. 2015 Aug;167A(8):1685-740. doi: 10.1002/ajmg.a.37107. Epub 2015 May 22.

PMID:
26010070
7.

Definition of critical periods for Hedgehog pathway antagonist-induced holoprosencephaly, cleft lip, and cleft palate.

Heyne GW, Melberg CG, Doroodchi P, Parins KF, Kietzman HW, Everson JL, Ansen-Wilson LJ, Lipinski RJ.

PLoS One. 2015 Mar 20;10(3):e0120517. doi: 10.1371/journal.pone.0120517. eCollection 2015.

8.

Serotonin regulates calcium homeostasis in lactation by epigenetic activation of hedgehog signaling.

Laporta J, Keil KP, Weaver SR, Cronick CM, Prichard AP, Crenshaw TD, Heyne GW, Vezina CM, Lipinski RJ, Hernandez LL.

Mol Endocrinol. 2014 Nov;28(11):1866-74. doi: 10.1210/me.2014-1204. Epub 2014 Sep 5.

9.

Characterization of subtle brain abnormalities in a mouse model of Hedgehog pathway antagonist-induced cleft lip and palate.

Lipinski RJ, Holloway HT, O'Leary-Moore SK, Ament JJ, Pecevich SJ, Cofer GP, Budin F, Everson JL, Johnson GA, Sulik KK.

PLoS One. 2014 Jul 21;9(7):e102603. doi: 10.1371/journal.pone.0102603. eCollection 2014. Erratum in: PLoS One. 2014;9(8):e106607.

10.

The teratogenic effects of prenatal ethanol exposure are exacerbated by Sonic Hedgehog or GLI2 haploinsufficiency in the mouse.

Kietzman HW, Everson JL, Sulik KK, Lipinski RJ.

PLoS One. 2014 Feb 19;9(2):e89448. doi: 10.1371/journal.pone.0089448. eCollection 2014.

11.

Ethanol-induced face-brain dysmorphology patterns are correlative and exposure-stage dependent.

Lipinski RJ, Hammond P, O'Leary-Moore SK, Ament JJ, Pecevich SJ, Jiang Y, Budin F, Parnell SE, Suttie M, Godin EA, Everson JL, Dehart DB, Oguz I, Holloway HT, Styner MA, Johnson GA, Sulik KK.

PLoS One. 2012;7(8):e43067. doi: 10.1371/journal.pone.0043067. Epub 2012 Aug 22.

12.

Magnetic resonance-based imaging in animal models of fetal alcohol spectrum disorder.

O'Leary-Moore SK, Parnell SE, Lipinski RJ, Sulik KK.

Neuropsychol Rev. 2011 Jun;21(2):167-85. doi: 10.1007/s11065-011-9164-z. Epub 2011 Mar 29. Review.

13.

Identification of Hedgehog signaling inhibitors with relevant human exposure by small molecule screening.

Lipinski RJ, Bushman W.

Toxicol In Vitro. 2010 Aug;24(5):1404-9. doi: 10.1016/j.tiv.2010.04.011. Epub 2010 Apr 29.

14.

Cleft lip and palate results from Hedgehog signaling antagonism in the mouse: Phenotypic characterization and clinical implications.

Lipinski RJ, Song C, Sulik KK, Everson JL, Gipp JJ, Yan D, Bushman W, Rowland IJ.

Birth Defects Res A Clin Mol Teratol. 2010 Apr;88(4):232-40. doi: 10.1002/bdra.20656.

15.

Genesis of teratogen-induced holoprosencephaly in mice.

Lipinski RJ, Godin EA, O'leary-Moore SK, Parnell SE, Sulik KK.

Am J Med Genet C Semin Med Genet. 2010 Feb 15;154C(1):29-42. doi: 10.1002/ajmg.c.30239. Review.

16.

Hedgehog pathway responsiveness correlates with the presence of primary cilia on prostate stromal cells.

Zhang J, Lipinski RJ, Gipp JJ, Shaw AK, Bushman W.

BMC Dev Biol. 2009 Oct 7;9:50. doi: 10.1186/1471-213X-9-50.

17.

Establishment and characterization of immortalized Gli-null mouse embryonic fibroblast cell lines.

Lipinski RJ, Bijlsma MF, Gipp JJ, Podhaizer DJ, Bushman W.

BMC Cell Biol. 2008 Sep 13;9:49. doi: 10.1186/1471-2121-9-49.

18.

Dose- and route-dependent teratogenicity, toxicity, and pharmacokinetic profiles of the hedgehog signaling antagonist cyclopamine in the mouse.

Lipinski RJ, Hutson PR, Hannam PW, Nydza RJ, Washington IM, Moore RW, Girdaukas GG, Peterson RE, Bushman W.

Toxicol Sci. 2008 Jul;104(1):189-97. doi: 10.1093/toxsci/kfn076. Epub 2008 Apr 14.

19.

Identification and characterization of several dietary alkaloids as weak inhibitors of hedgehog signaling.

Lipinski RJ, Dengler E, Kiehn M, Peterson RE, Bushman W.

Toxicol Sci. 2007 Dec;100(2):456-63. Epub 2007 Aug 28.

PMID:
17728282
20.

Unique and complimentary activities of the Gli transcription factors in Hedgehog signaling.

Lipinski RJ, Gipp JJ, Zhang J, Doles JD, Bushman W.

Exp Cell Res. 2006 Jul 1;312(11):1925-38. Epub 2006 Mar 29.

PMID:
16571352

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