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Items: 1 to 20 of 84


Col4a1 mutations cause progressive retinal neovascular defects and retinopathy.

Alavi MV, Mao M, Pawlikowski BT, Kvezereli M, Duncan JL, Libby RT, John SW, Gould DB.

Sci Rep. 2016 Jan 27;6:18602. doi: 10.1038/srep18602.


Novel axon projection after stress and degeneration in the Dscam mutant retina.

Fernandes KA, Bloomsburg SJ, Miller CJ, Billingslea SA, Merrill MM, Burgess RW, Libby RT, Fuerst PG.

Mol Cell Neurosci. 2016 Mar;71:1-12. doi: 10.1016/j.mcn.2015.12.003. Epub 2015 Dec 10.


Strain-Dependent Anterior Segment Dysgenesis and Progression to Glaucoma in Col4a1 Mutant Mice.

Mao M, Smith RS, Alavi MV, Marchant JK, Cosma M, Libby RT, John SW, Gould DB.

Invest Ophthalmol Vis Sci. 2015 Oct;56(11):6823-31. doi: 10.1167/iovs.15-17527.


Quantitative measurement of retinal ganglion cell populations via histology-based random forest classification.

Hedberg-Buenz A, Christopher MA, Lewis CJ, Fernandes KA, Dutca LM, Wang K, Scheetz TE, Abràmoff MD, Libby RT, Garvin MK, Anderson MG.

Exp Eye Res. 2016 May;146:370-85. doi: 10.1016/j.exer.2015.09.011. Epub 2015 Oct 22.


Dysregulated miRNA biogenesis downstream of cellular stress and ALS-causing mutations: a new mechanism for ALS.

Emde A, Eitan C, Liou LL, Libby RT, Rivkin N, Magen I, Reichenstein I, Oppenheim H, Eilam R, Silvestroni A, Alajajian B, Ben-Dov IZ, Aebischer J, Savidor A, Levin Y, Sons R, Hammond SM, Ravits JM, Möller T, Hornstein E.

EMBO J. 2015 Nov 3;34(21):2633-51. doi: 10.15252/embj.201490493. Epub 2015 Sep 1.


Using genetic mouse models to gain insight into glaucoma: Past results and future possibilities.

Fernandes KA, Harder JM, Williams PA, Rausch RL, Kiernan AE, Nair KS, Anderson MG, John SW, Howell GR, Libby RT.

Exp Eye Res. 2015 Dec;141:42-56. doi: 10.1016/j.exer.2015.06.019. Epub 2015 Jun 24. Review.


Tumor necrosis factor alpha has an early protective effect on retinal ganglion cells after optic nerve crush.

Mac Nair CE, Fernandes KA, Schlamp CL, Libby RT, Nickells RW.

J Neuroinflammation. 2014 Nov 19;11:194. doi: 10.1186/s12974-014-0194-3.


DBA/2J mice are susceptible to diabetic nephropathy and diabetic exacerbation of IOP elevation.

Soto I, Howell GR, John CW, Kief JL, Libby RT, John SW.

PLoS One. 2014 Sep 10;9(9):e107291. doi: 10.1371/journal.pone.0107291. eCollection 2014.


DLK-dependent signaling is important for somal but not axonal degeneration of retinal ganglion cells following axonal injury.

Fernandes KA, Harder JM, John SW, Shrager P, Libby RT.

Neurobiol Dis. 2014 Sep;69:108-16. doi: 10.1016/j.nbd.2014.05.015. Epub 2014 May 27.


Phospholipid flippase ATP8A2 is required for normal visual and auditory function and photoreceptor and spiral ganglion cell survival.

Coleman JA, Zhu X, Djajadi HR, Molday LL, Smith RS, Libby RT, John SW, Molday RS.

J Cell Sci. 2014 Mar 1;127(Pt 5):1138-49. doi: 10.1242/jcs.145052. Epub 2014 Jan 10.


Focal damage to macaque photoreceptors produces persistent visual loss.

Strazzeri JM, Hunter JJ, Masella BD, Yin L, Fischer WS, DiLoreto DA Jr, Libby RT, Williams DR, Merigan WH.

Exp Eye Res. 2014 Feb;119:88-96. doi: 10.1016/j.exer.2013.11.001. Epub 2013 Dec 5.


Expression levels of DNA replication and repair genes predict regional somatic repeat instability in the brain but are not altered by polyglutamine disease protein expression or age.

Mason AG, Tomé S, Simard JP, Libby RT, Bammler TK, Beyer RP, Morton AJ, Pearson CE, La Spada AR.

Hum Mol Genet. 2014 Mar 15;23(6):1606-18. doi: 10.1093/hmg/ddt551. Epub 2013 Nov 3.


Adding metabolomics to the toolbox for studying retinal disease.

Howell GR, Libby RT.

Invest Ophthalmol Vis Sci. 2013 Jun 21;54(6):4260. doi: 10.1167/iovs.13-12479. No abstract available.


Notch2 regulates BMP signaling and epithelial morphogenesis in the ciliary body of the mouse eye.

Zhou Y, Tanzie C, Yan Z, Chen S, Duncan M, Gaudenz K, Li H, Seidel C, Lewis B, Moran A, Libby RT, Kiernan AE, Xie T.

Proc Natl Acad Sci U S A. 2013 May 28;110(22):8966-71. doi: 10.1073/pnas.1218145110. Epub 2013 May 15.


Transcription factors SOX4 and SOX11 function redundantly to regulate the development of mouse retinal ganglion cells.

Jiang Y, Ding Q, Xie X, Libby RT, Lefebvre V, Gan L.

J Biol Chem. 2013 Jun 21;288(25):18429-38. doi: 10.1074/jbc.M113.478503. Epub 2013 May 6.


JUN regulates early transcriptional responses to axonal injury in retinal ganglion cells.

Fernandes KA, Harder JM, Kim J, Libby RT.

Exp Eye Res. 2013 Jul;112:106-17. doi: 10.1016/j.exer.2013.04.021. Epub 2013 May 3.


Lack of C9ORF72 coding mutations supports a gain of function for repeat expansions in amyotrophic lateral sclerosis.

Harms MB, Cady J, Zaidman C, Cooper P, Bali T, Allred P, Cruchaga C, Baughn M, Libby RT, Pestronk A, Goate A, Ravits J, Baloh RH.

Neurobiol Aging. 2013 Sep;34(9):2234.e13-9. doi: 10.1016/j.neurobiolaging.2013.03.006. Epub 2013 Apr 16.


Deficiency in Bim, Bid and Bbc3 (Puma) do not prevent axonal injury induced death.

Harder JM, Libby RT.

Cell Death Differ. 2013 Jan;20(1):182. doi: 10.1038/cdd.2012.119. Epub 2012 Sep 21. No abstract available.


Mutations in a P-type ATPase gene cause axonal degeneration.

Zhu X, Libby RT, de Vries WN, Smith RS, Wright DL, Bronson RT, Seburn KL, John SW.

PLoS Genet. 2012;8(8):e1002853. doi: 10.1371/journal.pgen.1002853. Epub 2012 Aug 9.


BCL2L1 (BCL-X) promotes survival of adult and developing retinal ganglion cells.

Harder JM, Ding Q, Fernandes KA, Cherry JD, Gan L, Libby RT.

Mol Cell Neurosci. 2012 Aug;51(1-2):53-9. doi: 10.1016/j.mcn.2012.07.006. Epub 2012 Jul 24.

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