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A new functional method to choose the target lobe for lung volume reduction in emphysema - comparison with the conventional densitometric method.

Hetzel J, Boeckeler M, Horger M, Ehab A, Kloth C, Wagner R, Freitag L, Slebos DJ, Lewis RA, Haentschel M.

Int J Chron Obstruct Pulmon Dis. 2017 Aug 30;12:2621-2628. doi: 10.2147/COPD.S139304. eCollection 2017.


Discovery and mode of action of a novel analgesic β-toxin from the African spider Ceratogyrus darlingi.

Sousa SR, Wingerd JS, Brust A, Bladen C, Ragnarsson L, Herzig V, Deuis JR, Dutertre S, Vetter I, Zamponi GW, King GF, Alewood PF, Lewis RJ.

PLoS One. 2017 Sep 7;12(9):e0182848. doi: 10.1371/journal.pone.0182848. eCollection 2017.


Ciguatoxins Evoke Potent CGRP Release by Activation of Voltage-Gated Sodium Channel Subtypes NaV1.9, NaV1.7 and NaV1.1.

Touska F, Sattler S, Malsch P, Lewis RJ, Reeh PW, Zimmermann K.

Mar Drugs. 2017 Aug 30;15(9). pii: E269. doi: 10.3390/md15090269.


Erratum: Structural and conformational determinants of macrocycle cell permeability.

Over B, Matsson P, Tyrchan C, Artursson P, Doak BC, Foley MA, Hilgendorf C, Johnston SE, Lee MD 4th, Lewis RJ, McCarren P, Muncipinto G, Norinder U, Perry MWD, Duvall JR, Kihlberg J.

Nat Chem Biol. 2017 Jul 18;13(8):922. doi: 10.1038/nchembio0817-922a. No abstract available.


Performance and Safety of a New Ab Interno Gelatin Stent in Refractory Glaucoma at 12 Months.

Grover DS, Flynn WJ, Bashford KP, Lewis RA, Duh YJ, Nangia RS, Niksch B.

Am J Ophthalmol. 2017 Aug 4. pii: S0002-9394(17)30324-0. doi: 10.1016/j.ajo.2017.07.023. [Epub ahead of print]


CORRIGENDUM: The expanding clinical phenotype of Bosch-Boonstra-Schaaf optic atrophy syndrome: 20 new cases and possible genotype-phenotype correlations.

Chen CA, Bosch DGM, Cho ScM MT, Rosenfeld JA, Shinawi M, Lewis RA, Mann J, Jayakar P, Payne K, Walsh L, Moss T, Schreiber A, Schoonveld C, Monaghan KG, Elmslie F, Douglas G, Boonstra FN, Millan F, Cremers FPM, McKnight D, Richard G, Juusola J, Kendall F, Ramsey K, Anyane-Yeboa K, Malkin E, Chung WK, Niyazov D, Pascual JM, Walkiewicz M, Veluchamy V, Li C, Hisama FM, de Vries BBA, Schaaf C.

Genet Med. 2017 Aug;19(8):962. doi: 10.1038/gim.2017.12.


Screening and purification of natural products from actinomycetes that affect the cell shape of fission yeast.

Lewis RA, Li J, Allenby NEE, Errington J, Hayles J, Nurse P.

J Cell Sci. 2017 Sep 15;130(18):3173-3185. doi: 10.1242/jcs.194571. Epub 2017 Aug 3.


Cross-sectional analysis of a large cohort with X-linked Charcot-Marie-Tooth disease (CMTX1).

Panosyan FB, Laura M, Rossor AM, Pisciotta C, Piscosquito G, Burns J, Li J, Yum SW, Lewis RA, Day J, Horvath R, Herrmann DN, Shy ME, Pareyson D, Reilly MM, Scherer SS; Inherited Neuropathies Consortium—Rare Diseases Clinical Research Network (INC-RDCRN).

Neurology. 2017 Aug 29;89(9):927-935. doi: 10.1212/WNL.0000000000004296. Epub 2017 Aug 2.


The phenotypic variability of HK1-associated retinal dystrophy.

Yuan Z, Li B, Xu M, Chang EY, Li H, Yang L, Wu S, Soens ZT, Li Y, Wong LC, Lewis RA, Sui R, Chen R.

Sci Rep. 2017 Aug 1;7(1):7051. doi: 10.1038/s41598-017-07629-3.


Chronic inflammatory demyelinating polyneuropathy.

Lewis RA.

Curr Opin Neurol. 2017 Oct;30(5):508-512. doi: 10.1097/WCO.0000000000000481.


Sodium channels and pain: from toxins to therapies.

Cardoso FC, Lewis RJ.

Br J Pharmacol. 2017 Jul 27. doi: 10.1111/bph.13962. [Epub ahead of print] Review.


Clinically severe CACNA1A alleles affect synaptic function and neurodegeneration differentially.

Luo X, Rosenfeld JA, Yamamoto S, Harel T, Zuo Z, Hall M, Wierenga KJ, Pastore MT, Bartholomew D, Delgado MR, Rotenberg J, Lewis RA, Emrick L, Bacino CA, Eldomery MK, Coban Akdemir Z, Xia F, Yang Y, Lalani SR, Lotze T, Lupski JR, Lee B, Bellen HJ, Wangler MF; Members of the UDN.

PLoS Genet. 2017 Jul 24;13(7):e1006905. doi: 10.1371/journal.pgen.1006905. eCollection 2017 Jul.


Distinctions in gene-specific changes in DNA methylation in response to folic acid supplementation between women with normal weight and obesity.

Park HJ, Bailey LB, Shade DC, Hausman DB, Hohos NM, Meagher RB, Kauwell GP, Lewis RD, Smith AK.

Obes Res Clin Pract. 2017 Jul 18. pii: S1871-403X(17)30062-5. doi: 10.1016/j.orcp.2017.06.004. [Epub ahead of print]


Obese Versus Normal-Weight Late-Adolescent Females have Inferior Trabecular Bone Microarchitecture: A Pilot Case-Control Study.

Kindler JM, Pollock NK, Ross HL, Modlesky CM, Singh H, Laing EM, Lewis RD.

Calcif Tissue Int. 2017 Jul 14. doi: 10.1007/s00223-017-0303-2. [Epub ahead of print]


[Vestibular and visual stimulation : simultaneous perception or not ?]

Todic J, Guyot JP, Perez Fornos A, Cavuscens S, Ranieri M, Merfeld D, Lewis R, Guinand N.

Rev Med Suisse. 2016 Oct 5;12(533):1650-1652. French.


Prevalence and orthopedic management of foot and ankle deformities in Charcot-Marie-Tooth disease.

Laurá M, Singh D, Ramdharry G, Morrow J, Skorupinska M, Pareyson D, Burns J, Lewis RA, Scherer SS, Herrmann DN, Cullen N, Bradish C, Gaiani L, Martinelli N, Gibbons P, Pfeffer G, Phisitkul P, Wapner K, Sanders J, Flemister S, Shy ME, Reilly MM; Inherited Neuropathies Consortium.

Muscle Nerve. 2017 Jun 20. doi: 10.1002/mus.25724. [Epub ahead of print]


Saccharin Aza Bioisosteres-Synthesis and Preclinical Property Comparisons.

Chen Y, Aurell CJ, Pettersen A, Lewis RJ, Hayes MA, Lepistö M, Jonson AC, Leek H, Thunberg L.

ACS Med Chem Lett. 2017 May 1;8(6):672-677. doi: 10.1021/acsmedchemlett.7b00137. eCollection 2017 Jun 8.


Inhibition of human N- and T-type calcium channels by an ortho-phenoxyanilide derivative, MONIRO-1.

McArthur JR, Motin L, Gleeson EC, Spiller S, Lewis RJ, Duggan PJ, Tuck KL, Adams DJ.

Br J Pharmacol. 2017 Jun 13. doi: 10.1111/bph.13910. [Epub ahead of print]


Zinc Supplementation Does Not Alter Indicators of Insulin Secretion and Sensitivity in Black and White Female Adolescents.

Lobene AJ, Kindler JM, Jenkins NT, Pollock NK, Laing EM, Grider A, Lewis RD.

J Nutr. 2017 Jul;147(7):1296-1300. doi: 10.3945/jn.117.248013. Epub 2017 Jun 7.


Corrigendum: Pharmacological characterisation of the highly NaV1.7 selective spider venom peptide Pn3a.

Deuis JR, Dekan Z, Wingerd JS, Smith JJ, Munasinghe NR, Bhola RF, Imlach WL, Herzig V, Armstrong DA, Rosengren KJ, Bosmans F, Waxman SG, Dib-Hajj SD, Escoubas P, Minett MS, Christie MJ, King GF, Alewood PF, Lewis RJ, Wood JN, Vetter I.

Sci Rep. 2017 May 26;7:46816. doi: 10.1038/srep46816. No abstract available.

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