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Polysaccharides of Dendrobium officinale Kimura & Migo protect gastric mucosal cell against oxidative damage-induced apoptosis in vitro and in vivo.

Zeng Q, Ko CH, Siu WS, Li LF, Han XQ, Yang L, Bik-San Lau C, Hu JM, Leung PC.

J Ethnopharmacol. 2017 Jul 3. pii: S0378-8741(17)30766-3. doi: 10.1016/j.jep.2017.07.006. [Epub ahead of print]


Nanoparticle-encapsulated baicalein markedly modulates pro-inflammatory response in gingival epithelial cells.

Li X, Luo W, Ng TW, Leung PC, Zhang C, Leung KC, Jin L.

Nanoscale. 2017 Jun 26. doi: 10.1039/c7nr02546g. [Epub ahead of print]


Phoenixin-14 concentrations are increased in association with luteinizing hormone and nesfatin-1 concentrations in women with polycystic ovary syndrome.

Ullah K, Ur Rahman T, Wu DD, Lin XH, Liu Y, Guo XY, Leung PCK, Zhang RJ, Huang HF, Sheng JZ.

Clin Chim Acta. 2017 Jun 15;471:243-247. doi: 10.1016/j.cca.2017.06.013. [Epub ahead of print]


SMAD1/5 mediates bone morphogenetic protein 2-induced up-regulation of BAMBI expression in human granulosa-lutein cells.

Bai L, Chang HM, Cheng JC, Klausen C, Chu G, Leung PCK, Yang G.

Cell Signal. 2017 May 31;37:52-61. doi: 10.1016/j.cellsig.2017.05.017. [Epub ahead of print]


Brief Report: Progression of Atherosclerosis in HIV-Infected Individuals-Prospective Data From an Asian Cohort.

Lui G, Ma RCW, Chook P, Wong CK, Tam CHT, Chan MHM, Lee SS, Wong RYK, Cheung CSK, Choi KW, Leung PC, Wong KH, Chan KCW, Lee N.

J Acquir Immune Defic Syndr. 2017 Jun 1;75(2):198-202. doi: 10.1097/QAI.0000000000001358.


Sphingosine-1-phosphate promotes ovarian cancer cell proliferation by disrupting Hippo signaling.

Fan Q, Cheng Y, Chang HM, Deguchi M, Hsueh AJ, Leung PCK.

Oncotarget. 2017 Apr 18;8(16):27166-27176. doi: 10.18632/oncotarget.15677.


Whole extracts of Radix Achyranthis Bidentatae and Radix Cyathulae promote angiogenesis in human umbilical vein endothelial cells in vitro and in zebrafish in vivo.

Zhou X, Siu WS, Zhang C, Liu CL, Cheng L, Kwok HF, Fung CH, Tam JC, Lau CP, Lau CB, Leung PC, Hung LK, Ko CH.

Exp Ther Med. 2017 Mar;13(3):1032-1038. doi: 10.3892/etm.2017.4053. Epub 2017 Jan 17.


Evaluation of the combined use of metronomic zoledronic acid and Coriolus versicolor in intratibial breast cancer mouse model.

Ko CH, Yue GG, Gao S, Luo KW, Siu WS, Shum WT, Shiu HT, Lee JK, Li G, Leung PC, Evdokiou A, Lau CB.

J Ethnopharmacol. 2017 May 23;204:77-85. doi: 10.1016/j.jep.2017.04.007. Epub 2017 Apr 12.


TGFβ1 induces endometrial cancer cell adhesion and migration by up-regulating integrin αvβ3 via SMAD-independent MEK-ERK1/2 signaling.

Xiong S, Klausen C, Cheng JC, Leung PCK.

Cell Signal. 2017 Jun;34:92-101. doi: 10.1016/j.cellsig.2017.03.010. Epub 2017 Mar 21.


Progression of Atherosclerosis in HIV-infected Individuals - Prospective Data from an Asian Cohort.

Lui G, Ma RC, Chook P, Wong CK, Tam CH, Chan MH, Lee SS, Wong RY, Cheung CS, Choi KW, Leung PC, Wong KH, Chan KC, Lee N.

J Acquir Immune Defic Syndr. 2017 Mar 10. doi: 10.1097/QAI.0000000000001358. [Epub ahead of print]


Prevalence of Prediabetes Risk in Offspring Born to Mothers with Hyperandrogenism.

Tian S, Lin XH, Xiong YM, Liu ME, Yu TT, Lv M, Zhao W, Xu GF, Ding GL, Xu CM, Jin M, Feng C, Wu YT, Tan YJ, Gao Q, Zhang J, Li C, Ren J, Jin LY, Chen B, Zhu H, Zhang XY, Chen SC, Liu XM, Liu Y, Zhang JY, Wang L, Zhang P, Chen XJ, Jin L, Chen X, Meng YC, Wu DD, Lin H, Yang Q, Zhou CL, Li XZ, Wang YY, Xiang YQ, Liu ZW, Gao L, Chen LT, Pan HJ, Li R, Zhang FH, Xing LF, Zhu YM, Klausen C, Leung PC, Li JX, Sun F, Sheng JZ, Huang HF.

EBioMedicine. 2017 Feb;16:275-283. doi: 10.1016/j.ebiom.2017.01.011. Epub 2017 Jan 11.


The relationship between angiotensin-converting enzyme (ACE) insertion (I) / deletion (D) polymorphism, serum ACE activity and bone mineral density (BMD) in older Chinese.

Zhang YF, Wang H, Cheng Q, Qin L, Tang NL, Leung PC, Kwok TC.

J Renin Angiotensin Aldosterone Syst. 2017 Jan;18(1):1470320316688345. doi: 10.1177/1470320316688345.


Growth hormone-releasing hormone antagonist inhibits the invasiveness of human endometrial cancer cells by down-regulating twist and N-cadherin expression.

Wu HM, Huang HY, Schally AV, Chao A, Chou HH, Leung PC, Wang HS.

Oncotarget. 2017 Jan 17;8(3):4410-4421. doi: 10.18632/oncotarget.13877.


Bone morphogenetic protein 2 regulates cell-cell communication by down-regulating connexin43 expression in luteinized human granulosa cells.

Wu YT, Chang HM, Huang HF, Sheng JZ, Leung PC.

Mol Hum Reprod. 2017 Mar 1;23(3):155-165. doi: 10.1093/molehr/gaw078.


A traditional Chinese formula composed of Chuanxiong Rhizoma and Gastrodiae Rhizoma (Da Chuanxiong Formula) suppresses inflammatory response in LPS -induced RAW 264.7 cells through inhibition of NF-κB pathway.

Liu ZK, Ng CF, Shiu HT, Wong HL, Wong CW, Li KK, Zhang JF, Lam PK, Poon WS, Lau CB, Leung PC, Ko CH.

J Ethnopharmacol. 2017 Jan 20;196:20-28. doi: 10.1016/j.jep.2016.12.014. Epub 2016 Dec 11.


Sprouty2 inhibits amphiregulin-induced down-regulation of E-cadherin and cell invasion in human ovarian cancer cells.

Cheng JC, Chang HM, Xiong S, So WK, Leung PC.

Oncotarget. 2016 Dec 6;7(49):81645-81660. doi: 10.18632/oncotarget.13162.


In vitro drug release and percutaneous behavior of poloxamer-based hydrogel formulation containing traditional Chinese medicine.

Wang W, Hui PC, Wat E, Ng FS, Kan CW, Wang X, Wong EC, Hu H, Chan B, Lau CB, Leung PC.

Colloids Surf B Biointerfaces. 2016 Dec 1;148:526-532. doi: 10.1016/j.colsurfb.2016.09.036. Epub 2016 Sep 23.


Low Thyroid Hormone in Early Pregnancy Is Associated With an Increased Risk of Gestational Diabetes Mellitus.

Yang S, Shi FT, Leung PC, Huang HF, Fan J.

J Clin Endocrinol Metab. 2016 Nov;101(11):4237-4243. Epub 2016 Sep 1.


Effect of combined use of Fructus Schisandrae and statin on high-fat-diet-induced metabolic syndrome in rats.

Wat E, Ng CF, Liu CL, Zhang C, Koon CM, Lau CP, Wong CW, Pang KY, Zhang X, Fung KP, Lau CB, Leung PC.

Hong Kong Med J. 2016 Dec;22 Suppl 6(6):24-27. No abstract available.


Oocyte-somatic cell interactions in the human ovary-novel role of bone morphogenetic proteins and growth differentiation factors.

Chang HM, Qiao J, Leung PC.

Hum Reprod Update. 2016 Dec;23(1):1-18. Epub 2016 Oct 26. Review.

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