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Items: 1 to 20 of 40

1.

Identification of inhibitors synergizing gemcitabine sensitivity in the squamous subtype of pancreatic ductal adenocarcinoma (PDAC).

Er JL, Goh PN, Lee CY, Tan YJ, Hii LW, Mai CW, Chung FF, Leong CO.

Apoptosis. 2018 May 8. doi: 10.1007/s10495-018-1459-6. [Epub ahead of print]

PMID:
29740790
2.

E-cadherin: Its dysregulation in carcinogenesis and clinical implications.

Wong SHM, Fang CM, Chuah LH, Leong CO, Ngai SC.

Crit Rev Oncol Hematol. 2018 Jan;121:11-22. doi: 10.1016/j.critrevonc.2017.11.010. Epub 2017 Nov 20. Review.

PMID:
29279096
3.

A Bis-benzopyrroloisoquinoline Alkaloid Incorporating a Cyclobutane Core and a Chlorophenanthroindolizidine Alkaloid with Cytotoxic Activity from Ficus fistulosa var. tengerensis.

Al-Khdhairawi AAQ, Krishnan P, Mai CW, Chung FF, Leong CO, Yong KT, Chong KW, Low YY, Kam TS, Lim KH.

J Nat Prod. 2017 Oct 27;80(10):2734-2740. doi: 10.1021/acs.jnatprod.7b00500. Epub 2017 Sep 19.

PMID:
28926237
4.

Contrasting sirtuin and poly(ADP-ribose)polymerase activities of selected 2,4,6-trisubstituted benzimidazoles.

Yeong KY, Tan SC, Mai CW, Leong CO, Chung FF, Lee YK, Chee CF, Abdul Rahman N.

Chem Biol Drug Des. 2018 Jan;91(1):213-219. doi: 10.1111/cbdd.13072. Epub 2017 Aug 9.

PMID:
28719017
5.

Single-walled carbon nanotubes (SWCNTs) inhibit heat shock protein 90 (HSP90) signaling in human lung fibroblasts and keratinocytes.

Ong LC, Tan YF, Tan BS, Chung FF, Cheong SK, Leong CO.

Toxicol Appl Pharmacol. 2017 Aug 15;329:347-357. doi: 10.1016/j.taap.2017.06.024. Epub 2017 Jul 1.

PMID:
28673683
6.

Lutein improves cell viability and reduces Alu RNA accumulation in hydrogen peroxide challenged retinal pigment epithelial cells.

Chong YS, Mai CW, Leong CO, Wong LC.

Cutan Ocul Toxicol. 2018 Mar;37(1):52-60. doi: 10.1080/15569527.2017.1335748. Epub 2017 Jun 20.

PMID:
28554225
7.

Jerantinine A induces tumor-specific cell death through modulation of splicing factor 3b subunit 1 (SF3B1).

Chung FF, Tan PF, Raja VJ, Tan BS, Lim KH, Kam TS, Hii LW, Tan SH, See SJ, Tan YF, Wong LZ, Yam WK, Mai CW, Bradshaw TD, Leong CO.

Sci Rep. 2017 Feb 15;7:42504. doi: 10.1038/srep42504.

8.

Cudraflavone C Induces Tumor-Specific Apoptosis in Colorectal Cancer Cells through Inhibition of the Phosphoinositide 3-Kinase (PI3K)-AKT Pathway.

Soo HC, Chung FF, Lim KH, Yap VA, Bradshaw TD, Hii LW, Tan SH, See SJ, Tan YF, Leong CO, Mai CW.

PLoS One. 2017 Jan 20;12(1):e0170551. doi: 10.1371/journal.pone.0170551. eCollection 2017.

9.

Targeting Legumain As a Novel Therapeutic Strategy in Cancers.

Mai CW, Chung FF, Leong CO.

Curr Drug Targets. 2017;18(11):1259-1268. doi: 10.2174/1389450117666161216125344. Review.

PMID:
27993111
10.

Green synthesis of graphene-silver nanocomposites and its application as a potent marine antifouling agent.

Yee MS, Khiew PS, Chiu WS, Tan YF, Kok YY, Leong CO.

Colloids Surf B Biointerfaces. 2016 Dec 1;148:392-401. doi: 10.1016/j.colsurfb.2016.09.011. Epub 2016 Sep 9.

PMID:
27639489
11.

Assessment of infarct-specific cardiac motion dysfunction using modeling and multimodal magnetic resonance merging.

Leong CO, Liew YM, Bilgen M, Abdul Aziz YF, Chee KH, Chiam YK, Lim E.

J Magn Reson Imaging. 2017 Feb;45(2):525-534. doi: 10.1002/jmri.25390. Epub 2016 Jul 15.

PMID:
27418150
12.

Fibroblast growth factor receptor 4 (FGFR4) and fibroblast growth factor 19 (FGF19) autocrine enhance breast cancer cells survival.

Tiong KH, Tan BS, Choo HL, Chung FF, Hii LW, Tan SH, Khor NT, Wong SF, See SJ, Tan YF, Rosli R, Cheong SK, Leong CO.

Oncotarget. 2016 Sep 6;7(36):57633-57650. doi: 10.18632/oncotarget.9328.

13.

Cytochrome P450 2W1 (CYP2W1) in Colorectal Cancers.

Chung FF, Mai CW, Ng PY, Leong CO.

Curr Cancer Drug Targets. 2016;16(1):71-8. Review.

PMID:
26563883
14.

Antitumour benzothiazoles. Part 32: DNA adducts and double strand breaks correlate with activity; synthesis of 5F203 hydrogels for local delivery.

Stone EL, Citossi F, Singh R, Kaur B, Gaskell M, Farmer PB, Monks A, Hose C, Stevens MF, Leong CO, Stocks M, Kellam B, Marlow M, Bradshaw TD.

Bioorg Med Chem. 2015 Nov 1;23(21):6891-9. doi: 10.1016/j.bmc.2015.09.052. Epub 2015 Oct 3.

PMID:
26474663
15.

Metformin synergizes 5-fluorouracil, epirubicin, and cyclophosphamide (FEC) combination therapy through impairing intracellular ATP production and DNA repair in breast cancer stem cells.

Soo JS, Ng CH, Tan SH, Malik RA, Teh YC, Tan BS, Ho GF, See MH, Taib NA, Yip CH, Chung FF, Hii LW, Teo SH, Leong CO.

Apoptosis. 2015 Oct;20(10):1373-87. doi: 10.1007/s10495-015-1158-5.

PMID:
26276035
16.

Nutlin-3 sensitizes nasopharyngeal carcinoma cells to cisplatin-induced cytotoxicity.

Voon YL, Ahmad M, Wong PF, Husaini R, Ng WT, Leong CO, Lane DP, Khoo AS.

Oncol Rep. 2015 Oct;34(4):1692-700. doi: 10.3892/or.2015.4177. Epub 2015 Aug 5.

17.

Mutant p53-R273H mediates cancer cell survival and anoikis resistance through AKT-dependent suppression of BCL2-modifying factor (BMF).

Tan BS, Tiong KH, Choo HL, Chung FF, Hii LW, Tan SH, Yap IK, Pani S, Khor NT, Wong SF, Rosli R, Cheong SK, Leong CO.

Cell Death Dis. 2015 Jul 16;6:e1826. doi: 10.1038/cddis.2015.191.

18.

Regional assessment of LV wall in infarcted heart using tagged MRI and cardiac modelling.

Jahanzad Z, Liew YM, Bilgen M, McLaughlin RA, Leong CO, Chee KH, Aziz YF, Ung NM, Lai KW, Ng SC, Lim E.

Phys Med Biol. 2015 May 21;60(10):4015-31. doi: 10.1088/0031-9155/60/10/4015. Epub 2015 Apr 28.

PMID:
25919317
19.

Orofacial pain of muscular origin is not associated with herpes virus-6 infection: a pilot study.

Shoji Y, Choo HL, Leong CO, Oo AL, Townsend G.

J Oral Facial Pain Headache. 2014 Fall;28(4):346-9. doi: 10.11607/ofph.1095.

PMID:
25347170
20.

Toxicity of single-walled carbon nanotubes.

Ong LC, Chung FF, Tan YF, Leong CO.

Arch Toxicol. 2016 Jan;90(1):103-18. doi: 10.1007/s00204-014-1376-6. Epub 2014 Oct 2. Review.

PMID:
25273022

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