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Items: 1 to 20 of 187


Contingency and determinism in evolution: Replaying life's tape.

Blount ZD, Lenski RE, Losos JB.

Science. 2018 Nov 9;362(6415). pii: eaam5979. doi: 10.1126/science.aam5979. Review.


Analysis of bacterial genomes from an evolution experiment with horizontal gene transfer shows that recombination can sometimes overwhelm selection.

Maddamsetti R, Lenski RE.

PLoS Genet. 2018 Jan 31;14(1):e1007199. doi: 10.1371/journal.pgen.1007199. eCollection 2018 Jan.


Mutator genomes decay, despite sustained fitness gains, in a long-term experiment with bacteria.

Couce A, Caudwell LV, Feinauer C, Hindré T, Feugeas JP, Weigt M, Lenski RE, Schneider D, Tenaillon O.

Proc Natl Acad Sci U S A. 2017 Oct 24;114(43):E9026-E9035. doi: 10.1073/pnas.1705887114. Epub 2017 Oct 10.


Effects of Beneficial Mutations in pykF Gene Vary over Time and across Replicate Populations in a Long-Term Experiment with Bacteria.

Peng F, Widmann S, Wünsche A, Duan K, Donovan KA, Dobson RCJ, Lenski RE, Cooper TF.

Mol Biol Evol. 2018 Jan 1;35(1):202-210. doi: 10.1093/molbev/msx279.


The dynamics of molecular evolution over 60,000 generations.

Good BH, McDonald MJ, Barrick JE, Lenski RE, Desai MM.

Nature. 2017 Nov 2;551(7678):45-50. doi: 10.1038/nature24287. Epub 2017 Oct 18.


Evolution of organismal stoichiometry in a long-term experiment with Escherichia coli.

Turner CB, Wade BD, Meyer JR, Sommerfeld BA, Lenski RE.

R Soc Open Sci. 2017 Jul 19;4(7):170497. doi: 10.1098/rsos.170497. eCollection 2017 Jul.


Convergence and Divergence in a Long-Term Experiment with Bacteria.

Lenski RE.

Am Nat. 2017 Aug;190(S1):S57-S68. doi: 10.1086/691209. Epub 2017 Mar 1.


Experimental evolution and the dynamics of adaptation and genome evolution in microbial populations.

Lenski RE.

ISME J. 2017 Oct;11(10):2181-2194. doi: 10.1038/ismej.2017.69. Epub 2017 May 16. Review.


What is adaptation by natural selection? Perspectives of an experimental microbiologist.

Lenski RE.

PLoS Genet. 2017 Apr 20;13(4):e1006668. doi: 10.1371/journal.pgen.1006668. eCollection 2017 Apr. Review.


Core Genes Evolve Rapidly in the Long-term Evolution Experiment with Escherichia coli.

Maddamsetti R, Hatcher PJ, Green AG, Williams BL, Marks DS, Lenski RE.

Genome Biol Evol. 2017 Apr 4. doi: 10.1093/gbe/evx064. [Epub ahead of print]


Specificity of genome evolution in experimental populations of Escherichia coli evolved at different temperatures.

Deatherage DE, Kepner JL, Bennett AF, Lenski RE, Barrick JE.

Proc Natl Acad Sci U S A. 2017 Mar 7;114(10):E1904-E1912. doi: 10.1073/pnas.1616132114. Epub 2017 Feb 15.


Ecological speciation of bacteriophage lambda in allopatry and sympatry.

Meyer JR, Dobias DT, Medina SJ, Servilio L, Gupta A, Lenski RE.

Science. 2016 Dec 9;354(6317):1301-1304. Epub 2016 Nov 24.


Host coevolution alters the adaptive landscape of a virus.

Burmeister AR, Lenski RE, Meyer JR.

Proc Biol Sci. 2016 Sep 28;283(1839). pii: 20161528.


Metabolic modelling in a dynamic evolutionary framework predicts adaptive diversification of bacteria in a long-term evolution experiment.

Großkopf T, Consuegra J, Gaffé J, Willison JC, Lenski RE, Soyer OS, Schneider D.

BMC Evol Biol. 2016 Aug 20;16(1):163. doi: 10.1186/s12862-016-0733-x.


Tempo and mode of genome evolution in a 50,000-generation experiment.

Tenaillon O, Barrick JE, Ribeck N, Deatherage DE, Blanchard JL, Dasgupta A, Wu GC, Wielgoss S, Cruveiller S, Médigue C, Schneider D, Lenski RE.

Nature. 2016 Aug 11;536(7615):165-70. Epub 2016 Aug 1.


You lookin' at me?

Bergstrom CT, Wasik BR, Lenski RE.

Br J Clin Pharmacol. 2016 Oct;82(4):1149. doi: 10.1111/bcp.13036. Epub 2016 Jul 14. No abstract available.


Sustained fitness gains and variability in fitness trajectories in the long-term evolution experiment with Escherichia coli.

Lenski RE, Wiser MJ, Ribeck N, Blount ZD, Nahum JR, Morris JJ, Zaman L, Turner CB, Wade BD, Maddamsetti R, Burmeister AR, Baird EJ, Bundy J, Grant NA, Card KJ, Rowles M, Weatherspoon K, Papoulis SE, Sullivan R, Clark C, Mulka JS, Hajela N.

Proc Biol Sci. 2015 Dec 22;282(1821):20152292. doi: 10.1098/rspb.2015.2292.


Replaying Evolution to Test the Cause of Extinction of One Ecotype in an Experimentally Evolved Population.

Turner CB, Blount ZD, Lenski RE.

PLoS One. 2015 Nov 18;10(11):e0142050. doi: 10.1371/journal.pone.0142050. eCollection 2015.


Synonymous Genetic Variation in Natural Isolates of Escherichia coli Does Not Predict Where Synonymous Substitutions Occur in a Long-Term Experiment.

Maddamsetti R, Hatcher PJ, Cruveiller S, Médigue C, Barrick JE, Lenski RE.

Mol Biol Evol. 2015 Nov;32(11):2897-904. doi: 10.1093/molbev/msv161. Epub 2015 Jul 20.


From Here to Eternity--The Theory and Practice of a Really Long Experiment.

Fox JW, Lenski RE.

PLoS Biol. 2015 Jun 23;13(6):e1002185. doi: 10.1371/journal.pbio.1002185. eCollection 2015 Jun.

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