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Colonization with Helicobacter is concomitant with modified gut microbiota and drastic failure of the immune control of Mycobacterium tuberculosis.

Majlessi L, Sayes F, Bureau JF, Pawlik A, Michel V, Jouvion G, Huerre M, Severgnini M, Consolandi C, Peano C, Brosch R, Touati E, Leclerc C.

Mucosal Immunol. 2017 Feb 1. doi: 10.1038/mi.2016.140. [Epub ahead of print]


Bisacodyl and its cytotoxic activity on human glioblastoma stem-like cells. Implication of inositol 1,4,5-triphosphate receptor dependent calcium signaling.

Dong J, Aulestia FJ, Assad Kahn S, Zeniou M, Dubois LG, El-Habr EA, Daubeuf F, Tounsi N, Cheshier SH, Frossard N, Junier MP, Chneiweiss H, Néant I, Moreau M, Leclerc C, Haiech J, Kilhoffer MC.

Biochim Biophys Acta. 2017 Jun;1864(6):1018-1027. doi: 10.1016/j.bbamcr.2017.01.010. Epub 2017 Jan 18.


A Universal Influenza Vaccine Can Lead to Disease Exacerbation or Viral Control Depending on Delivery Strategies.

Bernelin-Cottet C, Deloizy C, Stanek O, Barc C, Bouguyon E, Urien C, Boulesteix O, Pezant J, Richard CA, Moudjou M, Da Costa B, Jouneau L, Chevalier C, Leclerc C, Sebo P, Bertho N, Schwartz-Cornil I.

Front Immunol. 2016 Dec 26;7:641. doi: 10.3389/fimmu.2016.00641. eCollection 2016.


Dynamics of three-dimensional telomere profiles of circulating tumor cells in patients with high-risk prostate cancer who are undergoing androgen deprivation and radiation therapies.

Wark L, Klonisch T, Awe J, LeClerc C, Dyck B, Quon H, Mai S.

Urol Oncol. 2017 Mar;35(3):112.e1-112.e11. doi: 10.1016/j.urolonc.2016.10.018. Epub 2016 Dec 10.


Past and present dynamics of sorghum and pearl millet diversity in Mount Kenya region.

Labeyrie V, Deu M, Dussert Y, Rono B, Lamy F, Marangu C, Kiambi D, Calatayud C, Coppens d'Eeckenbrugge G, Robert T, Leclerc C.

Evol Appl. 2016 Sep 23;9(10):1241-1257. eCollection 2016 Dec.


Large-scale synthesis and structural analysis of a synthetic glycopeptide dendrimer as an anti-cancer vaccine candidate.

Ganneau C, Simenel C, Emptas E, Courtiol T, Coïc YM, Artaud C, Dériaud E, Bonhomme F, Delepierre M, Leclerc C, Lo-Man R, Bay S.

Org Biomol Chem. 2016 Dec 20;15(1):114-123.


Skin-bacteria communication: Involvement of the neurohormone Calcitonin Gene Related Peptide (CGRP) in the regulation of Staphylococcus epidermidis virulence.

N'Diaye AR, Leclerc C, Kentache T, Hardouin J, Poc CD, Konto-Ghiorghi Y, Chevalier S, Lesouhaitier O, Feuilloley MG.

Sci Rep. 2016 Oct 14;6:35379. doi: 10.1038/srep35379.


CD4+ T Cells Recognizing PE/PPE Antigens Directly or via Cross Reactivity Are Protective against Pulmonary Mycobacterium tuberculosis Infection.

Sayes F, Pawlik A, Frigui W, Gröschel MI, Crommelynck S, Fayolle C, Cia F, Bancroft GJ, Bottai D, Leclerc C, Brosch R, Majlessi L.

PLoS Pathog. 2016 Jul 28;12(7):e1005770. doi: 10.1371/journal.ppat.1005770. eCollection 2016 Jul.


B cells promote tumor progression in a mouse model of HPV-mediated cervical cancer.

Tang A, Dadaglio G, Oberkampf M, Di Carlo S, Peduto L, Laubreton D, Desrues B, Sun CM, Montagutelli X, Leclerc C.

Int J Cancer. 2016 Sep 15;139(6):1358-71. doi: 10.1002/ijc.30169. Epub 2016 May 14.


Domestic Violence Reported to the Police: Correlates of Victims' Reporting Behavior and Support to Legal Proceedings.

Boivin R, Leclerc C.

Violence Vict. 2016;31(3):402-15. doi: 10.1891/0886-6708.VV-D-14-00076. Epub 2016 Apr 8.


The fully synthetic MAG-Tn3 therapeutic vaccine containing the tetanus toxoid-derived TT830-844 universal epitope provides anti-tumor immunity.

Laubreton D, Bay S, Sedlik C, Artaud C, Ganneau C, Dériaud E, Viel S, Puaux AL, Amigorena S, Gérard C, Lo-Man R, Leclerc C.

Cancer Immunol Immunother. 2016 Mar;65(3):315-25. doi: 10.1007/s00262-016-1802-0. Epub 2016 Feb 4.


Calcium signaling orchestrates glioblastoma development: Facts and conjunctures.

Leclerc C, Haeich J, Aulestia FJ, Kilhoffer MC, Miller AL, Néant I, Webb SE, Schaeffer E, Junier MP, Chneiweiss H, Moreau M.

Biochim Biophys Acta. 2016 Jun;1863(6 Pt B):1447-59. doi: 10.1016/j.bbamcr.2016.01.018. Epub 2016 Jan 28. Review.


Ca(2+) coding and decoding strategies for the specification of neural and renal precursor cells during development.

Moreau M, Néant I, Webb SE, Miller AL, Riou JF, Leclerc C.

Cell Calcium. 2016 Mar;59(2-3):75-83. doi: 10.1016/j.ceca.2015.12.003. Epub 2015 Dec 17. Review.


CRN13 candidate effectors from plant and animal eukaryotic pathogens are DNA-binding proteins which trigger host DNA damage response.

Ramirez-Garcés D, Camborde L, Pel MJ, Jauneau A, Martinez Y, Néant I, Leclerc C, Moreau M, Dumas B, Gaulin E.

New Phytol. 2016 Apr;210(2):602-17. doi: 10.1111/nph.13774. Epub 2015 Dec 24.


Seed exchange networks, ethnicity, and sorghum diversity.

Labeyrie V, Thomas M, Muthamia ZK, Leclerc C.

Proc Natl Acad Sci U S A. 2016 Jan 5;113(1):98-103. doi: 10.1073/pnas.1513238112. Epub 2015 Dec 22.


Ionic messengers in development and cancer.

Moreau M, Leclerc C.

Int J Dev Biol. 2015;59(7-9):257-60. doi: 10.1387/ijdb.150215mm.


The Quest for Anticancer Vaccines: Deciphering the Fine-Epitope Specificity of Cancer-Related Monoclonal Antibodies by Combining Microarray Screening and Saturation Transfer Difference NMR.

Coelho H, Matsushita T, Artigas G, Hinou H, Cañada FJ, Lo-Man R, Leclerc C, Cabrita EJ, Jiménez-Barbero J, Nishimura S, Garcia-Martín F, Marcelo F.

J Am Chem Soc. 2015 Oct 7;137(39):12438-41. doi: 10.1021/jacs.5b06787. Epub 2015 Sep 22.


Hspa9 is required for pronephros specification and formation in Xenopus laevis.

Gassié L, Lombard A, Moraldi T, Bibonne A, Leclerc C, Moreau M, Marlier A, Gilbert T.

Dev Dyn. 2015 Dec;244(12):1538-49. doi: 10.1002/dvdy.24344. Epub 2015 Sep 23.


Combined impacts of global changes on biodiversity across the USA.

Bellard C, Leclerc C, Courchamp F.

Sci Rep. 2015 Jul 7;5:11828. doi: 10.1038/srep11828.


Rapamycin Impairs Antitumor CD8+ T-cell Responses and Vaccine-Induced Tumor Eradication.

Chaoul N, Fayolle C, Desrues B, Oberkampf M, Tang A, Ladant D, Leclerc C.

Cancer Res. 2015 Aug 15;75(16):3279-91. doi: 10.1158/0008-5472.CAN-15-0454. Epub 2015 Jun 29.

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