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Items: 17


An Updated View on an Emerging Target: Selected Papers from the 8th International Conference on Protein Kinase CK2.

Jose J, Le-Borgne M, Pinna LA, Montenarh M.

Pharmaceuticals (Basel). 2017 Mar 23;10(2). pii: E33. doi: 10.3390/ph10020033.


In Search of Small Molecule Inhibitors Targeting the Flexible CK2 Subunit Interface.

Bestgen B, Belaid-Choucair Z, Lomberget T, Le Borgne M, Filhol O, Cochet C.

Pharmaceuticals (Basel). 2017 Feb 3;10(1). pii: E16. doi: 10.3390/ph10010016.


Development of Pharmacophore Model for Indeno[1,2-b]indoles as Human Protein Kinase CK2 Inhibitors and Database Mining.

Haidar S, Bouaziz Z, Marminon C, Laitinen T, Poso A, Le Borgne M, Jose J.

Pharmaceuticals (Basel). 2017 Jan 9;10(1). pii: E8. doi: 10.3390/ph10010008.


Crystal structure of 13-phenyl-2,3,4,13-tetra-hydro-1H-indazolo[1,2-b]phthalazine-1,6,11-trione.

Lamera E, Benzerka S, Bouraiou A, Bouacida S, Merazig H, Chibani A, Le Borgne M, Bouaziz Z.

Acta Crystallogr E Crystallogr Commun. 2015 Dec 12;71(Pt 12):o1036-7. doi: 10.1107/S2056989015023452. eCollection 2015 Dec 1.


Real-Time Analysis of Calcium Signals during the Early Phase of T Cell Activation Using a Genetically Encoded Calcium Biosensor.

Le Borgne M, Raju S, Zinselmeyer BH, Le VT, Li J, Wang Y, Miller MJ, Shaw AS.

J Immunol. 2016 Feb 15;196(4):1471-9. doi: 10.4049/jimmunol.1502414. Epub 2016 Jan 8.


1st Joint European Conference on Therapeutic Targets and Medicinal Chemistry (TTMC 2015).

Le Borgne M, Haidar S, Duval O, Wünsch B, Jose J.

Pharmaceuticals (Basel). 2015 Dec 26;9(1). pii: E1. doi: 10.3390/ph9010001.


Once Upon a Time: The Adaptive Immune Response in Atherosclerosis--a Fairy Tale No More.

Le Borgne M, Caligiuri G, Nicoletti A.

Mol Med. 2015 Oct 27;21 Suppl 1:S13-8. doi: 10.2119/molmed.2015.00027. Review.


Phenolic indeno[1,2-b]indoles as ABCG2-selective potent and non-toxic inhibitors stimulating basal ATPase activity.

Gozzi GJ, Bouaziz Z, Winter E, Daflon-Yunes N, Honorat M, Guragossian N, Marminon C, Valdameri G, Bollacke A, Guillon J, Pinaud N, Marchivie M, Cadena SM, Jose J, Le Borgne M, Di Pietro A.

Drug Des Devel Ther. 2015 Jul 3;9:3481-95. doi: 10.2147/DDDT.S84982. eCollection 2015.


High precision zinc isotopic measurements applied to mouse organs.

Moynier F, Le Borgne M.

J Vis Exp. 2015 May 22;(99):e52479. doi: 10.3791/52479.


Functional display of heterotetrameric human protein kinase CK2 on Escherichia coli: a novel tool for drug discovery.

Gratz A, Bollacke A, Stephan S, Nienberg C, Le Borgne M, Götz C, Jose J.

Microb Cell Fact. 2015 Jun 3;14:74. doi: 10.1186/s12934-015-0263-z.


An integrative modeling framework reveals plasticity of TGF-β signaling.

Andrieux G, Le Borgne M, Théret N.

BMC Syst Biol. 2014 Mar 12;8:30. doi: 10.1186/1752-0509-8-30.


Kinase suppressor of Ras 1 is not required for the generation of regulatory and memory T cells.

Le Borgne M, Filbert EL, Shaw AS.

PLoS One. 2013;8(2):e57137. doi: 10.1371/journal.pone.0057137. Epub 2013 Feb 19.


Stathmin regulates microtubule dynamics and microtubule organizing center polarization in activated T cells.

Filbert EL, Le Borgne M, Lin J, Heuser JE, Shaw AS.

J Immunol. 2012 Jun 1;188(11):5421-7. doi: 10.4049/jimmunol.1200242. Epub 2012 Apr 23.


Dynamic regulation of Tgf-B signaling by Tif1γ: a computational approach.

Andrieux G, Fattet L, Le Borgne M, Rimokh R, Théret N.

PLoS One. 2012;7(3):e33761. doi: 10.1371/journal.pone.0033761. Epub 2012 Mar 23.


The impact of negative selection on thymocyte migration in the medulla.

Le Borgne M, Ladi E, Dzhagalov I, Herzmark P, Liao YF, Chakraborty AK, Robey EA.

Nat Immunol. 2009 Aug;10(8):823-30. doi: 10.1038/ni.1761. Epub 2009 Jun 21.


Inferring the role of transcription factors in regulatory networks.

Veber P, Guziolowski C, Le Borgne M, Radulescu O, Siegel A.

BMC Bioinformatics. 2008 May 6;9:228. doi: 10.1186/1471-2105-9-228.


Topology and static response of interaction networks in molecular biology.

Radulescu O, Lagarrigue S, Siegel A, Veber P, Le Borgne M.

J R Soc Interface. 2006 Feb 22;3(6):185-96.

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