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Items: 1 to 20 of 28


IL-1beta mediates MMP secretion and IL-1beta neosynthesis via upregulation of p22(phox) and NOX4 activity in human articular chondrocytes.

Rousset F, Hazane-Puch F, Pinosa C, Nguyen MV, Grange L, Soldini A, Rubens-Duval B, Dupuy C, Morel F, Lardy B.

Osteoarthritis Cartilage. 2015 Nov;23(11):1972-80. doi: 10.1016/j.joca.2015.02.167.


State of emergency preparedness for US health insurance plans.

Merchant RM, Finne K, Lardy B, Veselovskiy G, Korba C, Margolis GS, Lurie N.

Am J Manag Care. 2015 Jan;21(1):65-72.


[NADPH oxidase Nox4, a putative therapeutic target in osteoarthritis].

Morel F, Rousset F, Vu Chuong Nguyen M, Trocme C, Grange L, Lardy B.

Bull Acad Natl Med. 2015 Apr-May;199(4-5):673-86; discussion 686-7. Review. French.


[NADPH oxidases, Nox: new isoenzymes family].

Chuong Nguyen MV, Lardy B, Paclet MH, Rousset F, Berthier S, Baillet A, Grange L, Gaudin P, Morel F.

Med Sci (Paris). 2015 Jan;31(1):43-52. doi: 10.1051/medsci/20153101012. Epub 2015 Feb 6. Review. French.


Heme oxygenase-1 regulates matrix metalloproteinase MMP-1 secretion and chondrocyte cell death via Nox4 NADPH oxidase activity in chondrocytes.

Rousset F, Nguyen MV, Grange L, Morel F, Lardy B.

PLoS One. 2013 Jun 20;8(6):e66478. doi: 10.1371/journal.pone.0066478. Print 2013.


Quinone compounds regulate the level of ROS production by the NADPH oxidase Nox4.

Nguyen MV, Lardy B, Rousset F, Hazane-Puch F, Zhang L, Trocmé C, Serrander L, Krause KH, Morel F.

Biochem Pharmacol. 2013 Jun 1;85(11):1644-54. doi: 10.1016/j.bcp.2013.03.023. Epub 2013 Apr 9.


Rapid assessment of cardiovascular risk among users of smoking cessation drugs within the US Food and Drug Administration's Mini-Sentinel program.

Toh S, Baker MA, Brown JS, Kornegay C, Platt R; Mini-Sentinel Investigators.

JAMA Intern Med. 2013 May 13;173(9):817-9. doi: 10.1001/jamainternmed.2013.3004. No abstract available.


Success of program linking data sources to monitor H1N1 vaccine safety points to potential for even broader safety surveillance.

Salmon D, Yih WK, Lee G, Rosofsky R, Brown J, Vannice K, Tokars J, Roddy J, Ball R, Gellin B, Lurie N, Koh H, Platt R, Lieu T; PRISM Program Group.

Health Aff (Millwood). 2012 Nov;31(11):2518-27. doi: 10.1377/hlthaff.2012.0104.


Exploring health plan perspectives in collecting and using data on race, ethnicity, and language.

Gazmararian J, Carreón R, Olson N, Lardy B.

Am J Manag Care. 2012 Jul 1;18(7):e254-61.


Recombinant Nox4 cytosolic domain produced by a cell or cell-free base systems exhibits constitutive diaphorase activity.

Nguyen MV, Zhang L, Lhomme S, Mouz N, Lenormand JL, Lardy B, Morel F.

Biochem Biophys Res Commun. 2012 Mar 16;419(3):453-8. doi: 10.1016/j.bbrc.2012.01.136. Epub 2012 Feb 3.


The E-loop is involved in hydrogen peroxide formation by the NADPH oxidase Nox4.

Takac I, Schröder K, Zhang L, Lardy B, Anilkumar N, Lambeth JD, Shah AM, Morel F, Brandes RP.

J Biol Chem. 2011 Apr 15;286(15):13304-13. doi: 10.1074/jbc.M110.192138. Epub 2011 Feb 22.


New insight into the Nox4 subcellular localization in HEK293 cells: first monoclonal antibodies against Nox4.

Zhang L, Nguyen MV, Lardy B, Jesaitis AJ, Grichine A, Rousset F, Talbot M, Paclet MH, Qian G, Morel F.

Biochimie. 2011 Mar;93(3):457-68. doi: 10.1016/j.biochi.2010.11.001. Epub 2010 Nov 12.


Matrix metalloproteinases and diabetic foot ulcers: the ratio of MMP-1 to TIMP-1 is a predictor of wound healing.

Muller M, Trocme C, Lardy B, Morel F, Halimi S, Benhamou PY.

Diabet Med. 2008 Apr;25(4):419-26. doi: 10.1111/j.1464-5491.2008.02414.x.


Concerted activities of nitric oxide synthases and NADPH oxidases in PLB-985 cells.

Verchier Y, Lardy B, Nguyen MV, Morel F, Arbault S, Amatore C.

Biochem Biophys Res Commun. 2007 Sep 21;361(2):493-8. Epub 2007 Jul 20.


NOX4 activity is determined by mRNA levels and reveals a unique pattern of ROS generation.

Serrander L, Cartier L, Bedard K, Banfi B, Lardy B, Plastre O, Sienkiewicz A, Fórró L, Schlegel W, Krause KH.

Biochem J. 2007 Aug 15;406(1):105-14.


NOX family NADPH oxidases: not just in mammals.

Bedard K, Lardy B, Krause KH.

Biochimie. 2007 Sep;89(9):1107-12. Epub 2007 Feb 20. Review.


New insights into the membrane topology of the phagocyte NADPH oxidase: characterization of an anti-gp91-phox conformational monoclonal antibody.

Campion Y, Paclet MH, Jesaitis AJ, Marques B, Grichine A, Berthier S, Lenormand JL, Lardy B, Stasia MJ, Morel F.

Biochimie. 2007 Sep;89(9):1145-58. Epub 2007 Feb 20.


NAD(P)H oxidase activity of Nox4 in chondrocytes is both inducible and involved in collagenase expression.

Grange L, Nguyen MV, Lardy B, Derouazi M, Campion Y, Trocme C, Paclet MH, Gaudin P, Morel F.

Antioxid Redox Signal. 2006 Sep-Oct;8(9-10):1485-96. Erratum in: Antioxid Redox Signal. 2006 Nov-Dec;8(11-12):2193.


Specific host genes required for the killing of Klebsiella bacteria by phagocytes.

Benghezal M, Fauvarque MO, Tournebize R, Froquet R, Marchetti A, Bergeret E, Lardy B, Klein G, Sansonetti P, Charette SJ, Cosson P.

Cell Microbiol. 2006 Jan;8(1):139-48.


NADPH oxidase homologs are required for normal cell differentiation and morphogenesis in Dictyostelium discoideum.

Lardy B, Bof M, Aubry L, Paclet MH, Morel F, Satre M, Klein G.

Biochim Biophys Acta. 2005 Jun 30;1744(2):199-212. Epub 2005 Mar 8.

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