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Predictive factors of radiological progression after 2 years of remission-steered treatment in early arthritis patients: a post hoc analysis of the IMPROVED study.

Akdemir G, Verheul MK, Heimans L, Wevers-de Boer KV, Goekoop-Ruiterman YP, van Oosterhout M, Harbers JB, Bijkerk C, Steup-Beekman GM, Lard LR, Huizinga TW, Trouw LA, Allaart CF.

RMD Open. 2016 Feb 15;2(1):e000172. doi: 10.1136/rmdopen-2015-000172. eCollection 2016.


Two-year results of disease activity score (DAS)-remission-steered treatment strategies aiming at drug-free remission in early arthritis patients (the IMPROVED-study).

Heimans L, Akdemir G, Boer KV, Goekoop-Ruiterman YP, Molenaar ET, van Groenendael JH, Peeters AJ, Steup-Beekman GM, Lard LR, de Sonnaville PB, Grillet BA, Huizinga TW, Allaart CF.

Arthritis Res Ther. 2016 Jan 21;18:23. doi: 10.1186/s13075-015-0912-y.


Health-related quality of life and functional ability in patients with early arthritis during remission steered treatment: results of the IMPROVED study.

Heimans L, Wevers-de Boer KV, Koudijs KK, Visser K, Goekoop-Ruiterman YP, Harbers JB, Steup-Beekman GM, Lard LR, Grillet BA, Huizinga TW, Allaart CF.

Arthritis Res Ther. 2013 Oct 31;15(5):R173. doi: 10.1186/ar4361.


Just another case of Sjogren's syndrome?

Lard LR, Huizinga TW.

J Rheumatol. 2010 Jun;37(6):1363. doi: 10.3899/jrheum.100027. No abstract available.


A pitfall in screening with decoy cells after simultaneous pancreas kidney transplantation.

Lard LR, van der Boog PJ, Veselic M, Vossen AC, de Fijter JW, Groeneveld JH.

Clin Transplant. 2008 Nov-Dec;22(6):833-6. doi: 10.1111/j.1399-0012.2008.00874.x. Epub 2008 Aug 18.


Efficacy of methotrexate treatment in patients with probable rheumatoid arthritis: a double-blind, randomized, placebo-controlled trial.

van Dongen H, van Aken J, Lard LR, Visser K, Ronday HK, Hulsmans HM, Speyer I, Westedt ML, Peeters AJ, Allaart CF, Toes RE, Breedveld FC, Huizinga TW.

Arthritis Rheum. 2007 May;56(5):1424-32.


Functional regulatory immune responses against human cartilage glycoprotein-39 in health vs. proinflammatory responses in rheumatoid arthritis.

van Bilsen JH, van Dongen H, Lard LR, van der Voort EI, Elferink DG, Bakker AM, Miltenburg AM, Huizinga TW, de Vries RR, Toes RE.

Proc Natl Acad Sci U S A. 2004 Dec 7;101(49):17180-5. Epub 2004 Nov 29.


Comparison of the baseline disease activity of early oligo- and polyarthritis in sequential years.

Jansen LM, van der Horst-Bruinsma IE, van Schaardenburg D, Lard LR, Hazes JM, Huizinga TW, Dijkmans BA.

Clin Exp Rheumatol. 2004 Jul-Aug;22(4):447-52.


Miscarriage but not fecundity is associated with progression of joint destruction in rheumatoid arthritis.

van Dunné FM, Lard LR, Rook D, Helmerhorst FM, Huizinga TW.

Ann Rheum Dis. 2004 Aug;63(8):956-60.


Radiological outcome after four years of early versus delayed treatment strategy in patients with recent onset rheumatoid arthritis.

van Aken J, Lard LR, le Cessie S, Hazes JM, Breedveld FC, Huizinga TW.

Ann Rheum Dis. 2004 Mar;63(3):274-9.


Matrix metalloproteinases-3, -8, -9 as markers of disease activity and joint damage progression in early rheumatoid arthritis.

Tchetverikov I, Lard LR, DeGroot J, Verzijl N, TeKoppele JM, Breedveld FC, Huizinga TW, Hanemaaijer R.

Ann Rheum Dis. 2003 Nov;62(11):1094-9.


Influence of glucocorticoids and disease activity on total and high density lipoprotein cholesterol in patients with rheumatoid arthritis.

Boers M, Nurmohamed MT, Doelman CJ, Lard LR, Verhoeven AC, Voskuyl AE, Huizinga TW, van de Stadt RJ, Dijkmans BA, van der Linden S.

Ann Rheum Dis. 2003 Sep;62(9):842-5.


Association of the -2849 interleukin-10 promoter polymorphism with autoantibody production and joint destruction in rheumatoid arthritis.

Lard LR, van Gaalen FA, Schonkeren JJ, Pieterman EJ, Stoeken G, Vos K, Nelissen RG, Westendorp RG, Hoeben RC, Breedveld FC, Toes RE, Huizinga TW.

Arthritis Rheum. 2003 Jul;48(7):1841-8.


Genetic drift as an explanation for the reduced incidence of rheumatoid arthritis.

Huizinga TW, Linn-Rasker S, Lard LR, Westendorp RG.

Arthritis Rheum. 2002 Nov;46(11):3107. No abstract available.


Early and aggressive treatment of rheumatoid arthritis patients affects the association of HLA class II antigens with progression of joint damage.

Lard LR, Boers M, Verhoeven A, Vos K, Visser H, Hazes JM, Zwinderman AH, Schreuder GM, Breedveld FC, De Vries RR, van der Linden S, Zanelli E, Huizinga TW.

Arthritis Rheum. 2002 Apr;46(4):899-905.


Low adjusted-dose acenocoumarol therapy in sickle cell disease: a pilot study.

Schnog JB, Kater AP, Mac Gillavry MR, Duits AJ, Lard LR, van Der Dijs FP, Brandjes DP, ten Cate H, van Eps LW, Rojer RA.

Am J Hematol. 2001 Nov;68(3):179-83.


Early versus delayed treatment in patients with recent-onset rheumatoid arthritis: comparison of two cohorts who received different treatment strategies.

Lard LR, Visser H, Speyer I, vander Horst-Bruinsma IE, Zwinderman AH, Breedveld FC, Hazes JM.

Am J Med. 2001 Oct 15;111(6):446-51.


Delayed referral of female patients with rheumatoid arthritis.

Lard LR, Huizinga TW, Hazes JM, Vliet Vlieland TP.

J Rheumatol. 2001 Oct;28(10):2190-2.


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