Sort by
Items per page

Send to

Choose Destination

Search results

Items: 1 to 20 of 35


Murine GPRC6A Mediates Cellular Responses to L-Amino Acids, but Not Osteocalcin Variants.

Rueda P, Harley E, Lu Y, Stewart GD, Fabb S, Diepenhorst N, Cremers B, Rouillon MH, Wehrle I, Geant A, Lamarche G, Leach K, Charman WN, Christopoulos A, Summers RJ, Sexton PM, Langmead CJ.

PLoS One. 2016 Jan 19;11(1):e0146846. doi: 10.1371/journal.pone.0146846. eCollection 2016.


Automated parameter estimation for biological models using Bayesian statistical model checking.

Hussain F, Langmead CJ, Mi Q, Dutta-Moscato J, Vodovotz Y, Jha SK.

BMC Bioinformatics. 2015;16 Suppl 17:S8. doi: 10.1186/1471-2105-16-S17-S8. Epub 2015 Dec 7.


Dynamic allostery governs cyclophilin A-HIV capsid interplay.

Lu M, Hou G, Zhang H, Suiter CL, Ahn J, Byeon IJ, Perilla JR, Langmead CJ, Hung I, Gor'kov PL, Gan Z, Brey W, Aiken C, Zhang P, Schulten K, Gronenborn AM, Polenova T.

Proc Natl Acad Sci U S A. 2015 Nov 24;112(47):14617-22. doi: 10.1073/pnas.1516920112. Epub 2015 Nov 9.


Learning sequence determinants of protein:protein interaction specificity with sparse graphical models.

Kamisetty H, Ghosh B, Langmead CJ, Bailey-Kellogg C.

J Comput Biol. 2015 Jun;22(6):474-86. doi: 10.1089/cmb.2014.0289. Epub 2015 May 14.


Learning Sequence Determinants of Protein:protein Interaction Specificity with Sparse Graphical Models.

Kamisetty H, Ghosh B, Langmead CJ, Bailey-Kellogg C.

Res Comput Mol Biol. 2014;8394:129-143.


Parameter discovery in stochastic biological models using simulated annealing and statistical model checking.

Hussain F, Jha SK, Jha S, Langmead CJ.

Int J Bioinform Res Appl. 2014;10(4-5):519-39. doi: 10.1504/IJBRA.2014.062998.


Generative models of conformational dynamics.

Langmead CJ.

Adv Exp Med Biol. 2014;805:87-105. doi: 10.1007/978-3-319-02970-2_4. Review.


Efficient modeling and active learning discovery of biological responses.

Naik AW, Kangas JD, Langmead CJ, Murphy RF.

PLoS One. 2013 Dec 17;8(12):e83996. doi: 10.1371/journal.pone.0083996. eCollection 2013.


Monoclonal anti-β1-adrenergic receptor antibodies activate G protein signaling in the absence of β-arrestin recruitment.

Hutchings CJ, Cseke G, Osborne G, Woolard J, Zhukov A, Koglin M, Jazayeri A, Pandya-Pathak J, Langmead CJ, Hill SJ, Weir M, Marshall FH.

MAbs. 2014 Jan-Feb;6(1):246-61.


The Marker State Space (MSS) method for classifying clinical samples.

Fallon BP, Curnutte B, Maupin KA, Partyka K, Choi S, Brand RE, Langmead CJ, Tembe W, Haab BB.

PLoS One. 2013 Jun 4;8(6):e65905. doi: 10.1371/journal.pone.0065905. Print 2013.


Binding kinetics differentiates functional antagonism of orexin-2 receptor ligands.

Mould R, Brown J, Marshall FH, Langmead CJ.

Br J Pharmacol. 2014 Jan;171(2):351-63. doi: 10.1111/bph.12245.


Supra-physiological efficacy at GPCRs: superstition or super agonists?

Langmead CJ, Christopoulos A.

Br J Pharmacol. 2013 May;169(2):353-6. doi: 10.1111/bph.12142.


Pharmacology and structure of isolated conformations of the adenosine A₂A receptor define ligand efficacy.

Bennett KA, Tehan B, Lebon G, Tate CG, Weir M, Marshall FH, Langmead CJ.

Mol Pharmacol. 2013 May;83(5):949-58. doi: 10.1124/mol.112.084509. Epub 2013 Feb 19.


A minimal ligand binding pocket within a network of correlated mutations identified by multiple sequence and structural analysis of G protein coupled receptors.

Moitra S, Tirupula KC, Klein-Seetharaman J, Langmead CJ.

BMC Biophys. 2012 Jun 29;5:13. doi: 10.1186/2046-1682-5-13.


Exploring behaviors of stochastic differential equation models of biological systems using change of measures.

Jha SK, Langmead CJ.

BMC Bioinformatics. 2012 Apr 12;13 Suppl 5:S8. doi: 10.1186/1471-2105-13-S5-S8.


Learning generative models of molecular dynamics.

Razavian NS, Kamisetty H, Langmead CJ.

BMC Genomics. 2012;13 Suppl 1:S5. doi: 10.1186/1471-2164-13-S1-S5. Epub 2012 Jan 17.


Serum biomarker profiles as diagnostic tools in lung cancer.

Nolen BM, Langmead CJ, Choi S, Lomakin A, Marrangoni A, Bigbee WL, Weissfeld JL, Wilson DO, Dacic S, Siegfried JM, Lokshin AE.

Cancer Biomark. 2011-2012;10(1):3-12. doi: 10.3233/CBM-2012-0229.


Identification of novel adenosine A(2A) receptor antagonists by virtual screening.

Langmead CJ, Andrews SP, Congreve M, Errey JC, Hurrell E, Marshall FH, Mason JS, Richardson CM, Robertson N, Zhukov A, Weir M.

J Med Chem. 2012 Mar 8;55(5):1904-9. doi: 10.1021/jm201455y. Epub 2012 Feb 23.


Discovery of 1,2,4-triazine derivatives as adenosine A(2A) antagonists using structure based drug design.

Congreve M, Andrews SP, Doré AS, Hollenstein K, Hurrell E, Langmead CJ, Mason JS, Ng IW, Tehan B, Zhukov A, Weir M, Marshall FH.

J Med Chem. 2012 Mar 8;55(5):1898-903. doi: 10.1021/jm201376w. Epub 2012 Jan 27.


Progress in structure based drug design for G protein-coupled receptors.

Congreve M, Langmead CJ, Mason JS, Marshall FH.

J Med Chem. 2011 Jul 14;54(13):4283-311. doi: 10.1021/jm200371q. Epub 2011 Jun 15. Review. No abstract available.

Supplemental Content

Loading ...
Support Center