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Items: 1 to 20 of 209


Systematic evaluation of CS-Rosetta for membrane protein structure prediction with sparse NOE restraints.

Reichel K, Fisette O, Braun T, Lange OF, Hummer G, Schäfer LV.

Proteins. 2017 May;85(5):812-826. doi: 10.1002/prot.25224. Epub 2017 Feb 28.


TALE-Like Effectors Are an Ancestral Feature of the Ralstonia solanacearum Species Complex and Converge in DNA Targeting Specificity.

Schandry N, de Lange O, Prior P, Lahaye T.

Front Plant Sci. 2016 Aug 17;7:1225. doi: 10.3389/fpls.2016.01225. eCollection 2016.


Regulatory Implications of Non-Trivial Splicing: Isoform 3 of Rab1A Shows Enhanced Basal Activity and Is Not Controlled by Accessory Proteins.

Schöppner P, Csaba G, Braun T, Daake M, Richter B, Lange OF, Zacharias M, Zimmer R, Haslbeck M.

J Mol Biol. 2016 Apr 24;428(8):1544-57. doi: 10.1016/j.jmb.2016.02.028. Epub 2016 Mar 4.


Trastuzumab in Esophagogastric Cancer: HER2-Testing and Treatment Reality outside Clinical Studies in Germany.

Merx K, Barreto Miranda M, Kellermann L, Mahlknecht U, Lange O, Gonnermann M, Hofheinz RD.

Gastroenterol Res Pract. 2016;2016:1028505. doi: 10.1155/2016/1028505. Epub 2016 Jan 28.


Combining Evolutionary Information and an Iterative Sampling Strategy for Accurate Protein Structure Prediction.

Braun T, Koehler Leman J, Lange OF.

PLoS Comput Biol. 2015 Dec 29;11(12):e1004661. doi: 10.1371/journal.pcbi.1004661. eCollection 2015 Dec.


DNA-binding proteins from marine bacteria expand the known sequence diversity of TALE-like repeats.

de Lange O, Wolf C, Thiel P, Krüger J, Kleusch C, Kohlbacher O, Lahaye T.

Nucleic Acids Res. 2015 Nov 16;43(20):10065-80. doi: 10.1093/nar/gkv1053. Epub 2015 Oct 19.


A Framework to Simplify Combined Sampling Strategies in Rosetta.

Porter JR, Weitzner BD, Lange OF.

PLoS One. 2015 Sep 18;10(9):e0138220. doi: 10.1371/journal.pone.0138220. eCollection 2015.


Application of Enhanced Sampling Monte Carlo Methods for High-Resolution Protein-Protein Docking in Rosetta.

Zhang Z, Schindler CE, Lange OF, Zacharias M.

PLoS One. 2015 Jun 8;10(6):e0125941. doi: 10.1371/journal.pone.0125941. eCollection 2015.


NMR Exchange Format: a unified and open standard for representation of NMR restraint data.

Gutmanas A, Adams PD, Bardiaux B, Berman HM, Case DA, Fogh RH, Güntert P, Hendrickx PM, Herrmann T, Kleywegt GJ, Kobayashi N, Lange OF, Markley JL, Montelione GT, Nilges M, Ragan TJ, Schwieters CD, Tejero R, Ulrich EL, Velankar S, Vranken WF, Wedell JR, Westbrook J, Wishart DS, Vuister GW.

Nat Struct Mol Biol. 2015 Jun;22(6):433-4. doi: 10.1038/nsmb.3041. No abstract available.


Side-binding proteins modulate actin filament dynamics.

Crevenna AH, Arciniega M, Dupont A, Mizuno N, Kowalska K, Lange OF, Wedlich-Söldner R, Lamb DC.

Elife. 2015 Feb 23;4. pii: e04599. doi: 10.7554/eLife.04599.


Frequency of dermatological side effects of continuous subcutaneous insulin infusion in children and adolescents with type 1 diabetes.

Binder E, Lange O, Edlinger M, Meraner D, Abt D, Moser C, Steichen E, Hofer SE.

Exp Clin Endocrinol Diabetes. 2015 Apr;123(4):260-4. doi: 10.1055/s-0034-1394381. Epub 2015 Jan 21.


Access to Cα backbone dynamics of biological solids by 13C T1 relaxation and molecular dynamics simulation.

Asami S, Porter JR, Lange OF, Reif B.

J Am Chem Soc. 2015 Jan 28;137(3):1094-100. doi: 10.1021/ja509367q. Epub 2015 Jan 15.


A hybrid NMR/SAXS-based approach for discriminating oligomeric protein interfaces using Rosetta.

Rossi P, Shi L, Liu G, Barbieri CM, Lee HW, Grant TD, Luft JR, Xiao R, Acton TB, Snell EH, Montelione GT, Baker D, Lange OF, Sgourakis NG.

Proteins. 2015 Feb;83(2):309-17. doi: 10.1002/prot.24719. Epub 2014 Dec 19.


The Q Exactive HF, a Benchtop mass spectrometer with a pre-filter, high-performance quadrupole and an ultra-high-field Orbitrap analyzer.

Scheltema RA, Hauschild JP, Lange O, Hornburg D, Denisov E, Damoc E, Kuehn A, Makarov A, Mann M.

Mol Cell Proteomics. 2014 Dec;13(12):3698-708. doi: 10.1074/mcp.M114.043489. Epub 2014 Oct 30.


Development of a GC/Quadrupole-Orbitrap mass spectrometer, part I: design and characterization.

Peterson AC, Hauschild JP, Quarmby ST, Krumwiede D, Lange O, Lemke RA, Grosse-Coosmann F, Horning S, Donohue TJ, Westphall MS, Coon JJ, Griep-Raming J.

Anal Chem. 2014 Oct 21;86(20):10036-43. doi: 10.1021/ac5014767. Epub 2014 Sep 10.


Site-specific analysis of heteronuclear Overhauser effects in microcrystalline proteins.

del Amo JM, Agarwal V, Sarkar R, Porter J, Asami S, Rübbelke M, Fink U, Xue Y, Lange OF, Reif B.

J Biomol NMR. 2014 Aug;59(4):241-9. doi: 10.1007/s10858-014-9843-1. Epub 2014 Jul 3.


Differential global structural changes in the core particle of yeast and mouse proteasome induced by ligand binding.

Arciniega M, Beck P, Lange OF, Groll M, Huber R.

Proc Natl Acad Sci U S A. 2014 Jul 1;111(26):9479-84. doi: 10.1073/pnas.1408018111. Epub 2014 Jun 16.


A mechanism for the auto-inhibition of hyperpolarization-activated cyclic nucleotide-gated (HCN) channel opening and its relief by cAMP.

Akimoto M, Zhang Z, Boulton S, Selvaratnam R, VanSchouwen B, Gloyd M, Accili EA, Lange OF, Melacini G.

J Biol Chem. 2014 Aug 8;289(32):22205-20. doi: 10.1074/jbc.M114.572164. Epub 2014 May 30.


A prospective cohort study on the impact of darbepoetin alfa on quality of life in daily practice following anemia treatment guideline revisions.

Steinmetz T, Kindler M, Lange O, Vehling-Kaiser U, Kuhn A, Hellebrand E.

Curr Med Res Opin. 2014 Sep;30(9):1813-20. doi: 10.1185/03007995.2014.924914. Epub 2014 Jun 5.


Robust and highly accurate automatic NOESY assignment and structure determination with Rosetta.

Zhang Z, Porter J, Tripsianes K, Lange OF.

J Biomol NMR. 2014 Jul;59(3):135-45. doi: 10.1007/s10858-014-9832-4. Epub 2014 May 21.


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