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Items: 1 to 20 of 62

1.

Metabolomics enables precision medicine: "A White Paper, Community Perspective".

Beger RD, Dunn W, Schmidt MA, Gross SS, Kirwan JA, Cascante M, Brennan L, Wishart DS, Oresic M, Hankemeier T, Broadhurst DI, Lane AN, Suhre K, Kastenmüller G, Sumner SJ, Thiele I, Fiehn O, Kaddurah-Daouk R; for “Precision Medicine and Pharmacometabolomics Task Group”-Metabolomics Society Initiative..

Metabolomics. 2016;12(10):149. Epub 2016 Sep 2.

2.

Distinctly perturbed metabolic networks underlie differential tumor tissue damages induced by immune modulator β-glucan in a two-case ex vivo non-small-cell lung cancer study.

Fan TW, Warmoes MO, Sun Q, Song H, Turchan-Cholewo J, Martin JT, Mahan A, Higashi RM, Lane AN.

Cold Spring Harb Mol Case Stud. 2016 Jul;2(4):a000893. doi: 10.1101/mcs.a000893.

3.

Preclinical models for interrogating drug action in human cancers using Stable Isotope Resolved Metabolomics (SIRM).

Lane AN, Higashi RM, Fan TW.

Metabolomics. 2016 Jul;12(7). pii: 118. Epub 2016 Jun 29.

4.

Medical imaging and consent: when is an X-ray assault?

Lane AN.

J Med Radiat Sci. 2016 Jun;63(2):133-7. doi: 10.1002/jmrs.172. Epub 2016 May 9. Review.

5.

Stable Isotope Resolved Metabolomics Studies in Ex Vivo TIssue Slices.

Fan TW, Lane AN, Higashi RM.

Bio Protoc. 2016 Feb 5;6(3). pii: e1730.

6.

Applications of NMR spectroscopy to systems biochemistry.

Fan TW, Lane AN.

Prog Nucl Magn Reson Spectrosc. 2016 Feb;92-93:18-53. doi: 10.1016/j.pnmrs.2016.01.005. Epub 2016 Feb 6. Review.

7.

SDHB-Deficient Cancers: The Role of Mutations That Impair Iron Sulfur Cluster Delivery.

Saxena N, Maio N, Crooks DR, Ricketts CJ, Yang Y, Wei MH, Fan TW, Lane AN, Sourbier C, Singh A, Killian JK, Meltzer PS, Vocke CD, Rouault TA, Linehan WM.

J Natl Cancer Inst. 2016 Jan;108(1). doi: 10.1093/jnci/djv287.

8.

13C Tracer Studies of Metabolism in Mouse Tumor Xenografts.

Lane AN, Yan J, Fan TW.

Bio Protoc. 2015 Nov 20;5(22). pii: bio-protocol.org/e1650.

9.

Dectin-1 Activation by a Natural Product β-Glucan Converts Immunosuppressive Macrophages into an M1-like Phenotype.

Liu M, Luo F, Ding C, Albeituni S, Hu X, Ma Y, Cai Y, McNally L, Sanders MA, Jain D, Kloecker G, Bousamra M 2nd, Zhang HG, Higashi RM, Lane AN, Fan TW, Yan J.

J Immunol. 2015 Nov 15;195(10):5055-65. doi: 10.4049/jimmunol.1501158. Epub 2015 Oct 9. Erratum in: J Immunol. 2016 May 1;196(9):3968.

10.

Regulation of mammalian nucleotide metabolism and biosynthesis.

Lane AN, Fan TW.

Nucleic Acids Res. 2015 Feb 27;43(4):2466-85. doi: 10.1093/nar/gkv047. Epub 2015 Jan 27. Review.

11.

Chemoselective detection and discrimination of carbonyl-containing compounds in metabolite mixtures by 1H-detected 15N nuclear magnetic resonance.

Lane AN, Arumugam S, Lorkiewicz PK, Higashi RM, Laulhé S, Nantz MH, Moseley HN, Fan TW.

Magn Reson Chem. 2015 May;53(5):337-43. doi: 10.1002/mrc.4199. Epub 2015 Jan 23.

12.

Pyruvate carboxylase is critical for non-small-cell lung cancer proliferation.

Sellers K, Fox MP, Bousamra M 2nd, Slone SP, Higashi RM, Miller DM, Wang Y, Yan J, Yuneva MO, Deshpande R, Lane AN, Fan TW.

J Clin Invest. 2015 Feb;125(2):687-98. doi: 10.1172/JCI72873. Epub 2015 Jan 20.

13.

Stable isotope-labeled tracers for metabolic pathway elucidation by GC-MS and FT-MS.

Higashi RM, Fan TW, Lorkiewicz PK, Moseley HN, Lane AN.

Methods Mol Biol. 2014;1198:147-67. doi: 10.1007/978-1-4939-1258-2_11.

14.

Development and in silico evaluation of large-scale metabolite identification methods using functional group detection for metabolomics.

Mitchell JM, Fan TW, Lane AN, Moseley HN.

Front Genet. 2014 Jul 28;5:237. doi: 10.3389/fgene.2014.00237. eCollection 2014.

15.
16.

Knockdown of malic enzyme 2 suppresses lung tumor growth, induces differentiation and impacts PI3K/AKT signaling.

Ren JG, Seth P, Clish CB, Lorkiewicz PK, Higashi RM, Lane AN, Fan TW, Sukhatme VP.

Sci Rep. 2014 Jun 24;4:5414. doi: 10.1038/srep05414.

17.

Structural insights into the evolution of a sexy protein: novel topology and restricted backbone flexibility in a hypervariable pheromone from the red-legged salamander, Plethodon shermani.

Wilburn DB, Bowen KE, Doty KA, Arumugam S, Lane AN, Feldhoff PW, Feldhoff RC.

PLoS One. 2014 May 21;9(5):e96975. doi: 10.1371/journal.pone.0096975. eCollection 2014.

18.

Targeting lactate dehydrogenase--a inhibits tumorigenesis and tumor progression in mouse models of lung cancer and impacts tumor-initiating cells.

Xie H, Hanai J, Ren JG, Kats L, Burgess K, Bhargava P, Signoretti S, Billiard J, Duffy KJ, Grant A, Wang X, Lorkiewicz PK, Schatzman S, Bousamra M 2nd, Lane AN, Higashi RM, Fan TW, Pandolfi PP, Sukhatme VP, Seth P.

Cell Metab. 2014 May 6;19(5):795-809. doi: 10.1016/j.cmet.2014.03.003. Epub 2014 Apr 10.

19.

Role in tumor growth of a glycogen debranching enzyme lost in glycogen storage disease.

Guin S, Pollard C, Ru Y, Ritterson Lew C, Duex JE, Dancik G, Owens C, Spencer A, Knight S, Holemon H, Gupta S, Hansel D, Hellerstein M, Lorkiewicz P, Lane AN, Fan TW, Theodorescu D.

J Natl Cancer Inst. 2014 Apr 3;106(5). pii: dju062. doi: 10.1093/jnci/dju062.

20.

Metabolic reprogramming for producing energy and reducing power in fumarate hydratase null cells from hereditary leiomyomatosis renal cell carcinoma.

Yang Y, Lane AN, Ricketts CJ, Sourbier C, Wei MH, Shuch B, Pike L, Wu M, Rouault TA, Boros LG, Fan TW, Linehan WM.

PLoS One. 2013 Aug 15;8(8):e72179. doi: 10.1371/journal.pone.0072179. eCollection 2013.

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